scholarly journals Disrupted subject-specific gray matter network properties and cognitive dysfunction in type 1 diabetes patients with and without proliferative retinopathy

2015 ◽  
Vol 37 (3) ◽  
pp. 1194-1208 ◽  
Author(s):  
Eelco van Duinkerken ◽  
Richard G. Ijzerman ◽  
Martin Klein ◽  
Annette C. Moll ◽  
Frank J. Snoek ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Cognitive Dysfunction ◽  
Gray Matter ◽  
Proliferative Retinopathy ◽  
Subject Specific ◽  
Network Properties ◽  
Gray Matter Network ◽  
Diabetes Patients

The association between insulin resistance and proliferative retinopathy in type 1 diabetes

2015 ◽  
Vol 53 (3) ◽  
pp. 261-266 ◽  
Author(s):  
Irina Duţă ◽  
Simona Fica ◽  
Daniela Adriana Ion
Keyword(s):  
Insulin Resistance ◽  
Type 1 Diabetes ◽  
Logistic Regression ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Proliferative Retinopathy ◽  
Stepwise Logistic Regression ◽  
The Relationship ◽  
Diabetes Patients

Abstract Introduction. Little is known about the relationship between insulin resistance and proliferative diabetic retinopathy in type 1 diabetes. The aim of this article is to explore the relationship between sight-threatening proliferative diabetic retinopathy and insulin resistance. Methods. This was a cross-sectional study that included 167 type 1 diabetes patients. Insulin resistance was assessed using eGDR (estimated glucose disposal rate) formula. Diabetic retinopathy was assessed by ophthalmoscopy using Early Treatment Diabetic Retinopathy classification. The association between eGDR and proliferative diabetic retinopathy was assessed in uni- and multivariate models using stepwise logistic regression of covariates. The contribution of individual predictors in the final regresion model was examined using Wald statistic. Results. Significantly lower eGDR’s values were observed in patients with proliferative diabetic retinopathy: 5.5 vs. 7 (p = 0.002). The results remained significant (p < 0.001) after adjusting for multiple covariates (sex, diabetes duration, body mass index, HDL cholesterol, LDL cholesterol, triglycerides, smoking). eGDR variable was retained in the final model of stepwise logistic regression (p < 0.001) and showed the strongest association with proliferative diabetic retinopathy (Wald = 12.73). Conclusions. In type 1 diabetes patients insulin resistance was the most important independent risk factor associated with diabetic proliferative retinopathy.

Evaluation of glycemia correction during sleeping on the somnological indicators in type 1 diabetes patients

2018 ◽  
Author(s):  
Ina Darashkevich ◽  
Tatiana Mokhort ◽  
Lola Nikanava ◽  
Serhey Tishkovsky
Keyword(s):  
Type 1 Diabetes ◽  
Diabetes Patients

253-LB: Effect of Combined Low Dose IL-2 plus Polyclonal Tregs in Type 1 Diabetes Patients

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 253-LB
Author(s):  
SHEN DONG ◽  
CODY T. MOWERY ◽  
KEVAN C. HEROLD ◽  
STEPHEN E. GITELMAN ◽  
JONATHAN H. ESENSTEN ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Low Dose ◽  
Diabetes Patients
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