scholarly journals Atlas-guided volumetric diffuse optical tomography enhanced by generalized linear model analysis to image risk decision-making responses in young adults

2014 ◽  
Vol 35 (8) ◽  
pp. 4249-4266 ◽  
Author(s):  
Zi-Jing Lin ◽  
Lin Li ◽  
Mary Cazzell ◽  
Hanli Liu
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Koji Miki ◽  
Masahiro Kitamura ◽  
Kodai Hatta ◽  
Kei Kamide ◽  
Yasuyuki Gondo ◽  
...  

AbstractPeriodontal disease is a chronic inflammatory condition that affects various peripheral organs. The periodontal inflamed surface area (PISA) quantifies periodontitis severity and the spread of inflammatory wounds. This study aimed to investigate the association between PISA and high-sensitivity C-reactive protein (hs-CRP), a systemic inflammation marker. This study included 250 community-dwelling septuagenarians (69–71 years). We collected information on their medical (e.g., diabetes and dyslipidemia) and dental examinations (e.g., measurement of the probing pocket depth). Generalized linear model analysis was used to explore the association between PISA and hs-CRP levels. There was a significant difference in hs-CRP levels between groups with PISA ≥ 500 and < 500 (p = 0.017). Moreover, the generalized linear model analysis revealed a significant association between PISA and hs-CRP levels (risk ratio = 1.77; p = 0.033) even after adjusting other factors. Further, we found a correlation between PISA and hs-CRP (Spearman’s rank correlation coefficient, rs = 0.181; p = 0.023). Our findings suggest that PISA is an effective index for estimating the effect of periodontitis on the whole body, enabling medical-dental cooperation.


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