scholarly journals Reduced anterior internal capsule white matter integrity in primary insomnia

2013 ◽  
Vol 35 (7) ◽  
pp. 3431-3438 ◽  
Author(s):  
Kai Spiegelhalder ◽  
Wolfram Regen ◽  
Martin Prem ◽  
Chiara Baglioni ◽  
Christoph Nissen ◽  
...  
Keyword(s):  
White Matter ◽  
Internal Capsule ◽  
Primary Insomnia ◽  
White Matter Integrity

scholarly journals Longitudinal deterioration of white-matter integrity: heterogeneity in the ageing population

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Konstantinos Poulakis ◽  
Robert I Reid ◽  
Scott A Przybelski ◽  
David S Knopman ◽  
Jonathan Graff-Radford ◽  
...  
Keyword(s):  
White Matter ◽  
Internal Capsule ◽  
Population Based ◽  
White Matter Integrity ◽  
Ageing Population ◽  
White Matter Tract ◽  
Imaging Data ◽  
Cognitive Assessments ◽  
Longitudinal Imaging ◽  
Systemic Health

Abstract Deterioration in white-matter health plays a role in cognitive ageing. Our goal was to discern heterogeneity of white-matter tract vulnerability in ageing using longitudinal imaging data (two to five imaging and cognitive assessments per participant) from a population-based sample of 553 elderly participants (age ≥60 years). We found that different clusters (healthy white matter, fast white-matter decliners and intermediate white-matter group) were heterogeneous in the spatial distribution of white-matter integrity, systemic health and cognitive trajectories. White-matter health of specific tracts (genu of corpus callosum, posterior corona radiata and anterior internal capsule) informed about cluster assignments. Not surprisingly, brain amyloidosis was not significantly different between clusters. Clusters had differential white-matter tract vulnerability to ageing (commissural fibres > association/brainstem fibres). Identification of vulnerable white-matter tracts is a valuable approach to assessing risk for cognitive decline.

scholarly journals Mini-Basketball Training Program Improves Social Communication and White Matter Integrity in Children with Autism

2020 ◽  
Vol 10 (11) ◽  
pp. 803
Author(s):  
Kelong Cai ◽  
Qian Yu ◽  
Fabian Herold ◽  
Zhimei Liu ◽  
Jingui Wang ◽  
...  
Keyword(s):  
White Matter ◽  
Training Program ◽  
Social Communication ◽  
Exercise Intervention ◽  
Internal Capsule ◽  
Children With Autism ◽  
Exercise Group ◽  
White Matter Integrity ◽  
Control Group ◽  
Children With Asd

Impairments in social communication (SC) represent one of the core symptoms of autism spectrum disorder (ASD). While previous studies have demonstrated that exercise intervention improves SC in children with ASD, there is currently no neuroscientific evidence supporting its benefits. Therefore, we evaluated the outcomes of a long-term exercise intervention on SC and white matter integrity (WMI) in children with ASD, and further explored the neural mechanism of exercise intervention on SC in these children. Twenty-nine children aged 3–6 years with ASD were assigned to either exercise group (n = 15) or control group (n = 14). The exercise group received a scheduled mini-basketball training program (5 sessions per week, forty minutes per session) for 12 consecutive weeks, while the control group was instructed to maintain their daily activities. Groups were assessed before and after intervention on SC and WMI. SC scores were lower in the exercise group post-intervention. Compared with the control group, WMI of the exercise group showed higher fractional anisotropy in the body of corpus callosum, fornix, right cerebral peduncle, left posterior limb of internal capsule, right retrolenticular part of internal capsule, left anterior corona radiate and left superior fronto-occipital fasciculus; lower mean diffusivity in the left anterior corona radiate and the bilateral corticospinal tract. Furthermore, increased WMI was associated with lower scores on a measure of social cognition in the overall sample. This study is the first to provide evidence that exercise intervention improves SC and white matter integrity in children with autism.

scholarly journals A template-based procedure for determining white matter integrity in the internal capsule early after stroke

2014 ◽  
Vol 4 ◽  
pp. 695-700 ◽  
Author(s):  
Matthew A. Petoe ◽  
Winston D. Byblow ◽  
Esther J.M. de Vries ◽  
Venkatesh Krishnamurthy ◽  
Cathy S. Zhong ◽  
...  
Keyword(s):  
White Matter ◽  
Internal Capsule ◽  
White Matter Integrity

Relationship between white matter integrity and post-traumatic cognitive deficits: a systematic review and meta-analysis

2018 ◽  
Vol 90 (1) ◽  
pp. 98-107 ◽  
Author(s):  
Jie Zhang ◽  
Liang Tian ◽  
Li Zhang ◽  
Ruidong Cheng ◽  
Ruili Wei ◽  
...  
Keyword(s):  
White Matter ◽  
Cognitive Deficits ◽  
Meta Analysis ◽  
Memory Function ◽  
Demographic Factors ◽  
Internal Capsule ◽  
White Matter Integrity ◽  
Cognitive Domains ◽  
Brain White Matter ◽  
Wide Range

ObjectiveTo investigate relationships between cognitive domains and white matter changes in different regions in patients with cognitive deficits after traumatic brain injury (TBI).MethodsDatabases including PubMed, Embase, Web of Science and CENTRAL were searched for studies published before 5 August 2017. Correlation coefficients between cognition and white matter integrity, measured by diffusion metrics, including fractional anisotropy (FA), were pooled from 49 studies including 1405 patients. The influence of demographic factors was assessed by meta-regression analysis.ResultsSignificant pooled FA–executive correlations (p<0.001) were found across various regions, including the corpus callosum (CC) (r=0.42, 95% CI 0.30 to 0.54), superior longitudinal fasciculus (r=0.50, 95% CI 0.41 to 0.59) and internal capsule (IC) (r=0.49, 95% CI 0.37 to 0.61). The fornix (r=0.62, 95% CI 0.45 to 0.78) and cingulum (r=0.57, 95% CI 0.34 to 0.81) particularly correlated with memory (p<0.001). The CC and IC also showed significant relationships with attention and processing speed (p<0.001). Demographic factors had no influence overall, except that studies with a greater proportion of males had stronger correlations between memory and white matter (p<0.05).ConclusionsFA is the most sensitive metric for detecting post-TBI cognitive decline across various domains. Representative white matter regions, such as the CC and IC, perform better than whole-brain white matter for reflecting a wide range of cognitive domains, including memory, attention and executive functions. Moreover, the fornix and cingulum particularly reflect memory function. They yield insights into particular imaging indicators that have neuropsychological value.

scholarly journals Regional White Matter Integrity Predicts Treatment Response to Escitalopram and Memantine in Geriatric Depression: A Pilot Study

2020 ◽  
Vol 11 ◽  
Author(s):  
Beatrix Krause-Sorio ◽  
Prabha Siddarth ◽  
Michaela M. Milillo ◽  
Roza Vlasova ◽  
Linda Ercoli ◽  
...  
Keyword(s):  
White Matter ◽  
Pilot Study ◽  
Treatment Response ◽  
White Matter Integrity ◽  
Geriatric Depression

White matter integrity after cannabidiol administration for treatment resistant epilepsy

2021 ◽  
Vol 172 ◽  
pp. 106603
Author(s):  
J.T. Houston ◽  
R. Nenert ◽  
J.B. Allendorfer ◽  
E.M. Bebin ◽  
T.E. Gaston ◽  
...  
Keyword(s):  
White Matter ◽  
White Matter Integrity ◽  
Treatment Resistant
Sign in / Sign up

Export Citation Format

Share Document