scholarly journals Differential language expertise related to white matter architecture in regions subserving sensory-motor coupling, articulation, and interhemispheric transfer

2010 ◽  
Vol 32 (12) ◽  
pp. 2064-2074 ◽  
Author(s):  
Stefan Elmer ◽  
Jürgen Hänggi ◽  
Martin Meyer ◽  
Lutz Jäncke
Keyword(s):  
White Matter ◽  
Interhemispheric Transfer ◽  
Sensory Motor

scholarly journals Natural variation in sensory-motor white matter organization influences manifestations of Huntington's disease

2016 ◽  
Vol 37 (12) ◽  
pp. 4615-4628 ◽  
Author(s):  
Michael Orth ◽  
Sarah Gregory ◽  
Rachael I Scahill ◽  
Isabella SM Mayer ◽  
Lora Minkova ◽  
...  
Keyword(s):  
White Matter ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Natural Variation ◽  
Sensory Motor

scholarly journals Neonatal neuropsychology: Emerging relations of neonatal sensory–motor responses to white matter integrity

2014 ◽  
Vol 62 ◽  
pp. 209-219 ◽  
Author(s):  
Maya Weinstein ◽  
Ronella Marom ◽  
Irit Berger ◽  
Dafna Ben Bashat ◽  
Varda Gross-Tsur ◽  
...  
Keyword(s):  
White Matter ◽  
White Matter Integrity ◽  
Motor Responses ◽  
Sensory Motor

scholarly journals Increased contrast of the grey-white matter boundary in the motor, visual and auditory areas in Autism Spectrum Disorders

2019 ◽  
Author(s):  
Marion Fouquet ◽  
Nicolas Traut ◽  
Anita Beggiato ◽  
Richard Delorme ◽  
Thomas Bourgeron ◽  
...  
Keyword(s):  
White Matter ◽  
Data Exchange ◽  
Primary Motor Cortex ◽  
Autism Spectrum ◽  
Imaging Data ◽  
Sensory Motor ◽  
Magnetic Resonance Imaging Mri ◽  
Brain Imaging Data

AbstractThe contrast of the interface between the neocortical grey matter and the white matter is emerging as an important neuroimaging phenotype for several brain disorders. To date, a single in vivo study has analysed the cortical grey-to-white matter percent contrast (GWPC) on Magnetic Resonance Imaging (MRI), and has shown a significant decrease of this contrast in several areas in individuals with Autism Spectrum Disorder (ASD). Our goal was to replicate this study across a larger cohort, using the multicenter data from the Autism Brain Imaging Data Exchange 1 and 2 gathering data from 2,148 subjects. Multiple linear regression was used to study the effect of the diagnosis of ASD on the GWPC. Contrary to the first study, we found a statistically significant increase of GWPC among individuals with ASD in left auditory and bilateral visual sensory areas, as well as in the left primary motor cortex. These results were still statistically significant after inclusion of cortical thickness as covariate. There are numerous reports of sensory-motor atypicalities in patients with ASD, which may be the reason for the differences in GWPC that we observed. Further investigation could help us determine the potential role of a defect or a delay in intra-cortical myelination of sensory-motor regions in ASD. Code: https://github.com/neuroanatomy/GWPC.

FT-IR microspectroscopic analysis of diseased white matter brain tissues

1995 ◽  
Vol 53 ◽  
pp. 968-969
Author(s):  
Steven M. Le Vine ◽  
David L. Wetzel
Keyword(s):  
White Matter ◽  
Gray Matter ◽  
Twitcher Mouse ◽  
Grid Pattern ◽  
Marked Contrast ◽  
Spatially Resolved ◽  
Ft Ir ◽  
Ir Microspectroscopy ◽  
Chemical Evidence

In situ FT-IR microspectroscopy has allowed spatially resolved interrogation of different parts of brain tissue. In previous work the spectrrscopic features of normal barin tissue were characterized. The white matter, gray matter and basal ganglia were mapped from appropriate peak area measurements from spectra obtained in a grid pattern. Bands prevalent in white matter were mostly associated with the lipid. These included 2927 and 1469 cm-1 due to CH2 as well as carbonyl at 1740 cm-1. Also 1235 and 1085 cm-1 due to phospholipid and galactocerebroside, respectively (Figs 1and2). Localized chemical changes in the white matter as a result of white matter diseases have been studied. This involved the documentation of localized chemical evidence of demyelination in shiverer mice in which the spectra of white matter lacked the marked contrast between it and gray matter exhibited in the white matter of normal mice (Fig. 3).The twitcher mouse, a model of Krabbe’s desease, was also studied. The purpose in this case was to look for a localized build-up of psychosine in the white matter caused by deficiencies in the enzyme responsible for its breakdown under normal conditions.

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