scholarly journals Noninvasive measurement of the cerebral blood flow response in human lateral geniculate nucleus with arterial spin labeling fMRI

2008 ◽  
Vol 29 (10) ◽  
pp. 1207-1214 ◽  
Author(s):  
Kun Lu ◽  
Joanna E. Perthen ◽  
Robert O. Duncan ◽  
Linda M. Zangwill ◽  
Thomas T. Liu
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Lateral Geniculate Nucleus ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Noninvasive Measurement ◽  
Blood Flow Response ◽  
Flow Response ◽  
Lateral Geniculate

Noninvasive Measurement of Cerebral Blood Flow Under Anesthesia Using Arterial Spin Labeling MRI

2016 ◽  
Vol 28 (4) ◽  
pp. 331-336 ◽  
Author(s):  
Lashmi Venkatraghavan ◽  
Julien Poublanc ◽  
Suparna Bharadwaj ◽  
Olivia Sobczyk ◽  
Adrian P. Crawley ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Noninvasive Measurement

Effect of caffeine on theophyliine on cerebral blood flow response to brain activation: In vitro and in vivo studies

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S198-S198
Author(s):  
Joseph R Meno ◽  
Thien-son K Nguyen ◽  
Elise M Jensen ◽  
G Alexander West ◽  
Leonid Groysman ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Brain Activation ◽  
In Vivo Studies ◽  
Blood Flow Response ◽  
Flow Response

scholarly journals N-acetyl cysteine administration affects cerebral blood flow as measured by Arterial Spin Labeling MRI in patients with multiple sclerosis

Heliyon ◽  
2021 ◽  
pp. e07615
Author(s):  
Shiva Shahrampour ◽  
Justin Heholt ◽  
Andrew Wang ◽  
Faezeh Vedaei ◽  
Feroze B. Mohamed ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Acetyl Cysteine

scholarly journals Hypoxia and Hypotension Transform the Blood Flow Response to Cortical Spreading Depression from Hyperemia into Hypoperfusion in the Rat

2008 ◽  
Vol 28 (7) ◽  
pp. 1369-1376 ◽  
Author(s):  
Inna Sukhotinsky ◽  
Ergin Dilekoz ◽  
Michael A Moskowitz ◽  
Cenk Ayata
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Cortical Spreading Depression ◽  
Spreading Depression ◽  
Ischemic Penumbra ◽  
Doppler Flowmetry ◽  
Blood Flow Response ◽  
Flow Response ◽  
Normal Rat ◽  
Cortex Cérébral

Cortical spreading depression (CSD) evokes a large cerebral blood flow (CBF) increase in normal rat brain. In contrast, in focal ischemic penumbra, CSD-like periinfarct depolarizations (PID) are mainly associated with hypoperfusion. Because PIDs electrophysiologically closely resemble CSD, we tested whether conditions present in ischemic penumbra, such as tissue hypoxia or reduced perfusion pressure, transform the CSD-induced CBF response in nonischemic rat cortex. Cerebral blood flow changes were recorded using laser Doppler flowmetry in rats subjected to hypoxia, hypotension, or both. Under normoxic normotensive conditions, CSD caused a characteristic transient CBF increase (74 ± 7%) occasionally preceded by a small hypoperfusion (−4 ± 2%). Both hypoxia ( pO2 45 ± 3 mm Hg) and hypotension (blood pressure 42 ± 2 mm Hg) independently augmented this initial hypoperfusion (−14 ± 2% normoxic hypotension; −16 ± 6% hypoxic normotension; −21 ± 5% hypoxic hypotension) and diminished the magnitude of hyperemia (44 ± 10% normoxic hypotension; 43 ± 9% hypoxic normotension; 27 ± 6% hypoxic hypotension). Hypotension and, to a much lesser extent, hypoxia increased the duration of hypoperfusion and the DC shift, whereas CSD amplitude remained unchanged. These results suggest that hypoxia and/or hypotension unmask a vasoconstrictive response during CSD in the rat such that, under nonphysiologic conditions (i.e., mimicking ischemic penumbra), the hyperemic response to CSD becomes attenuated resembling the blood flow response during PIDs.

scholarly journals Patient-Specific Detection of Cerebral Blood Flow Alterations as Assessed by Arterial Spin Labeling in Drug-Resistant Epileptic Patients

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0123975 ◽  
Author(s):  
Ilaria Boscolo Galazzo ◽  
Silvia Francesca Storti ◽  
Alessandra Del Felice ◽  
Francesca Benedetta Pizzini ◽  
Chiara Arcaro ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Patient Specific ◽  
Drug Resistant ◽  
Specific Detection ◽  
Epileptic Patients
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