scholarly journals Corpus callosal connection mapping using cortical gray matter parcellation and DT-MRI

2008 ◽  
Vol 29 (5) ◽  
pp. 503-516 ◽  
Author(s):  
Hae-Jeong Park ◽  
Jae Jin Kim ◽  
Seung-Koo Lee ◽  
Jeong Ho Seok ◽  
Jiwon Chun ◽  
...  
Keyword(s):  
Gray Matter ◽  
Cortical Gray Matter ◽  
Callosal Connection

Slowing of Cortical Gray Matter Atrophy with Teriflunomide is Associated with Delayed Conversion to Clinically Definite MS

2018 ◽  
Author(s):  
Robert Zivadinov ◽  
Michael G. Dwyer ◽  
Ellen Carl ◽  
Elizabeth M. Poole ◽  
Steve Cavalier ◽  
...  
Keyword(s):  
Gray Matter ◽  
Gray Matter Atrophy ◽  
Cortical Gray Matter

scholarly journals Reduced cortical gray matter volume in male adolescents with substance and conduct problems

2011 ◽  
Vol 118 (2-3) ◽  
pp. 295-305 ◽  
Author(s):  
Manish Dalwani ◽  
Joseph T. Sakai ◽  
Susan K. Mikulich-Gilbertson ◽  
Jody Tanabe ◽  
Kristen Raymond ◽  
...  
Keyword(s):  
Conduct Problems ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Male Adolescents ◽  
Matter Volume ◽  
Cortical Gray Matter

scholarly journals The Role of Electrode Size on the Incidence of Spreading Depression and on Cortical Cerebral Blood Flow as Measured by H2 Clearance

1992 ◽  
Vol 12 (2) ◽  
pp. 230-237 ◽  
Author(s):  
Marleen J. Verhaegen ◽  
Michael M. Todd ◽  
David S. Warner ◽  
Bruce James ◽  
Julie B. Weeks
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Gray Matter ◽  
Spreading Depression ◽  
Insertion Depth ◽  
Flow Measurements ◽  
Electrode Size ◽  
Cortical Gray Matter ◽  
The Right

Cerebral blood flow was measured by the H2 clearance method 30 and 60 min after the implantation of 300, 250, 125, or 50 μm diameter platinum–iridium electrodes 2 mm deep into the right parietal cortex of normothermic, normocarbic halothane-anesthetized rats. Another group of animals had 50 μm electrodes inserted 1 mm. In all animals, the presence or absence of a wave of spreading depression (SD) was noted at the time of implantation, with recordings made with glass micropipettes. H2 flow values were compared with those measured in gray matter from the same anatomical region (but from different rats), using [3H]nicotine. The incidence of SD ranged from 60% following insertion of 300 μm electrodes to 0% with 50 μm electrodes. H2 clearance flows also varied with electrode size, from 77 ± 21 ml 100 g−1 min−1 (mean ± standard deviation) with 300 μm electrodes to 110 ± 31 and 111 ± 16 ml 100 g−1 min−1 with 125 and 50 μm electrodes, respectively (insertion depth of 2 mm). A CBF value of 155 ± 60 ml 100 g−1 min−1 was obtained with 50 μm electrodes inserted only 1 mm. Cortical gray matter blood flow measured with [3H]nicotine was 154 ± 35 ml 100 g−1 min−1. When the role of SD in subsequent flow measurements was examined, there was a gradual increase in CBF between 30 and 60 min after electrode insertion in those animals with SD, while no such change was seen in rats without SD. These results indicate that the choice of electrode size and implantation depth influences the measurement of CBF by H2 clearance. CBF values equivalent to those obtained with isotopic techniques can be acutely obtained with small (50 μm diameter) electrodes inserted 1 mm into the cortex. While the occurrence of SD does influence CBF in the period immediately after implantation, a relationship between electrode size and measured flow is present that is independent of SD.

scholarly journals Early cortical gray matter loss and cognitive correlates in non-demented Parkinson's patients

2013 ◽  
Vol 19 (12) ◽  
pp. 1088-1093 ◽  
Author(s):  
Eun-Young Lee ◽  
Suman Sen ◽  
Paul J. Eslinger ◽  
Daymond Wagner ◽  
Michele L. Shaffer ◽  
...  
Keyword(s):  
Gray Matter ◽  
Cognitive Correlates ◽  
Cortical Gray Matter ◽  
Gray Matter Loss

Genetic Correlation Between Cortical Gray Matter Thickness and White Matter Connections

2018 ◽  
pp. 85-100
Author(s):  
Kaikai Shen ◽  
Vincent Doré ◽  
Jurgen Fripp ◽  
Stephen Rose ◽  
Katie L. McMahon ◽  
...  
Keyword(s):  
White Matter ◽  
Genetic Correlation ◽  
Gray Matter ◽  
Cortical Gray Matter

scholarly journals Genetic influences of cortical gray matter in language-related regions in healthy controls and schizophrenia

2011 ◽  
Vol 129 (2-3) ◽  
pp. 141-148 ◽  
Author(s):  
S. Jamadar ◽  
N.R. Powers ◽  
S.A. Meda ◽  
J. Gelernter ◽  
J.R. Gruen ◽  
...  
Keyword(s):  
Gray Matter ◽  
Genetic Influences ◽  
Healthy Controls ◽  
Cortical Gray Matter

scholarly journals Cocaine Decreases Cortical Cerebral Blood Flow but Does Not Obscure Regional Activation in Functional Magnetic Resonance Imaging in Human Subjects

1998 ◽  
Vol 18 (7) ◽  
pp. 724-734 ◽  
Author(s):  
Randy L. Gollub ◽  
Hans C. Breiter ◽  
Howard Kantor ◽  
David Kennedy ◽  
David Gastfriend ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Blood Flow ◽  
Gray Matter ◽  
Visual Stimulation ◽  
Bold Signal ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Before And After ◽  
Cortical Gray Matter ◽  
Cocaine Infusion

The authors used functional magnetic resonance imaging (fMRI) to determine whether acute intravenous (IV) cocaine use would change global cerebral blood flow (CBF) or visual stimulation-induced functional activation. They used flow-sensitive alternating inversion recovery (FAIR) scan sequences to measure CBF and blood oxygen level-dependent (BOLD) sensitive T2* scan sequences during visual stimulation to measure neuronal activation before and after cocaine and saline infusions. Cocaine (0.6 mg/kg IV over 30 seconds) increased heart rate and mean blood pressure and decreased end tidal carbon dioxide (CO2). All measures returned to baseline by 2 hours, the interinfusion interval, and were unchanged by saline. Flow-sensitive alternating inversion recovery imaging demonstrated that cortical gray matter CBF was unchanged after saline infusion (–2.4 ± 6.5%) but decreased (–14.1 ± 8.5%) after cocaine infusion (n = 8, P < 0.01). No decreases were detected in white matter, nor were changes found comparing BOLD signal intensity in cortical gray matter immediately before cocaine infusion with that measured 10 minutes after infusion. Visual stimulation resulted in comparable BOLD signal increases in visual cortex in all conditions (before and after cocaine and saline infusion). Despite a small (14%) but significant decrease in global cortical gray matter CBF after acute cocaine infusion, specific regional increases in BOLD imaging, mediated by neurons, can be measured reliably.

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