Is social functioning in older age patients with bipolar disorder associated with affective and/or non‐affective cognition?

2021 ◽  
Author(s):  
Nadine PG Paans ◽  
Nicole Korten ◽  
Melis Orhan ◽  
Anne Ensing ◽  
Sigfried NTM Schouws ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Social Functioning ◽  
Older Age

scholarly journals The functional impairment of different subtypes and occupational states in euthymic patients with bipolar disorder

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xinyu Liu ◽  
Xiaojuan Ma ◽  
Wenchen Wang ◽  
Jian Zhang ◽  
Xia Sun ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Social Functioning ◽  
Rating Scale ◽  
Verbal Learning ◽  
Occupational Status ◽  
Learning Performance ◽  
Neurocognitive Functioning ◽  
Type I ◽  
Speed Of Processing ◽  
Occupational Functioning

Abstract Background The aim was to explore the associations between clinical symptoms, demographic variables, social and neurocognitive functioning in euthymic patients with bipolar disorder (BD) stratified by subgroups of DSM-IV BD (type I (BD-I) and type II (BD-II)) and occupational status (employed/unemployed), and to highlight the significance of occupational status when assessing social and neurocognitive functioning in euthymic BD patients. Methods A total of 81 euthymic BD patients were participated in the study. The severity of the depressive and manic/hypomanic symptoms was measured using the 17-item Hamilton Depression Rating Scale (HDRS-17) and the Young Mania Rating Scale (YMRS), respectively. Social functioning and neurocognitive functioning were evaluated by the Functioning Assessment Short Test (FAST) and neurocognitive measures, respectively. Results Employed BD patients displayed greater social functioning (autonomy, occupational functioning, interpersonal relationship domain) and better verbal learning performance and speed of processing than unemployed BD patients. The correlation between neurocognitive functioning and social functioning was stronger in the employed group than in the unemployed group. There were no significant differences in neurocognitive and social functioning between the BD-I and BD-II groups, and the correlation between neurocognitive functioning and social functioning was similar between the BD-I and BD-II groups. Conclusion Employed BD patients may present greater occupational functioning and interpersonal relationships, as well as better verbal learning performance and speed of processing.

Physical comorbidity in Older-Age Bipolar Disorder (OABD) compared to the general population - a 3-year longitudinal prospective cohort study

2021 ◽  
Author(s):  
Alexandra J.M. Beunders ◽  
Almar A.L. Kok ◽  
Panagiotis C. Kosmas ◽  
Aartjan T.F. Beekman ◽  
Caroline M. Sonnenberg ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Cohort Study ◽  
General Population ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Older Age

Hostile attributions in bipolar disorder and schizophrenia contribute to poor social functioning

2015 ◽  
Vol 131 (6) ◽  
pp. 472-482 ◽  
Author(s):  
G. Lahera ◽  
S. Herrera ◽  
M. Reinares ◽  
A. Benito ◽  
M. Rullas ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Social Functioning ◽  
Hostile Attributions

scholarly journals Social Cognition, Language, and Social Behavior in 7-Year-Old Children at Familial High-Risk of Developing Schizophrenia or Bipolar Disorder: The Danish High Risk and Resilience Study VIA 7—A Population-Based Cohort Study

2019 ◽  
Vol 45 (6) ◽  
pp. 1218-1230 ◽  
Author(s):  
Camilla Jerlang Christiani ◽  
Jens R M Jepsen ◽  
Anne Thorup ◽  
Nicoline Hemager ◽  
Ditte Ellersgaard ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Social Cognition ◽  
Social Behavior ◽  
High Risk ◽  
Social Functioning ◽  
Population Based ◽  
Social Responsiveness ◽  
Developmental Phase ◽  
Bonferroni Correction ◽  
Familial High Risk

Abstract Objective To characterize social cognition, language, and social behavior as potentially shared vulnerability markers in children at familial high-risk of schizophrenia (FHR-SZ) and bipolar disorder (FHR-BP). Methods The Danish High-Risk and Resilience Study VIA7 is a multisite population-based cohort of 522 7-year-old children extracted from the Danish registries. The population-based controls were matched to the FHR-SZ children on age, sex, and municipality. The FHR-BP group followed same inclusion criteria. Data were collected blinded to familial high-risk status. Outcomes were social cognition, language, and social behavior. Results The analysis included 202 FHR-SZ children (girls: 46%), 120 FHR-BP children (girls: 46.7%), and 200 controls (girls: 46.5%). FHR-SZ children displayed significant deficits in language (receptive: d = −0.27, P = .006; pragmatic: d = −0.51, P < .001), social responsiveness (d = −0.54, P < .001), and adaptive social functioning (d = −0.47, P < .001) compared to controls after Bonferroni correction. Compared to FHR-BP children, FHR-SZ children performed significantly poorer on adaptive social functioning (d = −0.29, P = .007) after Bonferroni correction. FHR-BP and FHR-SZ children showed no significant social cognitive impairments compared to controls after Bonferroni correction. Conclusion Language, social responsiveness, and adaptive social functioning deficits seem associated with FHR-SZ but not FHR-BP in this developmental phase. The pattern of results suggests adaptive social functioning impairments may not be shared between FHR-BP and FHR-SZ in this developmental phase and thus not reflective of the shared risk factors for schizophrenia and bipolar disorder.

Older Age Bipolar Disorder

2018 ◽  
Vol 41 (1) ◽  
pp. 95-110 ◽  
Author(s):  
Annemiek Dols ◽  
Aartjan Beekman
Keyword(s):  
Bipolar Disorder ◽  
Older Age

Life course approach to understanding inequalities in health in later life

2017 ◽  
pp. 69-76 ◽  
Author(s):  
Ruth Bell ◽  
Michael Marmot
Keyword(s):  
Life Course ◽  
Social Functioning ◽  
Later Life ◽  
Older Age ◽  
Cognitive Changes ◽  
Healthy Life ◽  
Inequalities In Health ◽  
Biological Ageing ◽  
Life Course Approach ◽  
The Life Course

A long and healthy life is universally valued. The starkest inequalities in later life are how many years of life remain at an older age such as 65 years, and how many years of life that remain free from disabilities that impede physical, cognitive, and social functioning to the extent that they limit the sense of valuing one’s life. In this chapter we apply the frame of social determinants of health, using the life course approach to understand inequalities in health in later life. Healthy ageing is patterned by degrees of social advantage. Biological ageing, as revealed by physical and cognitive changes, is slower in people in better socioeconomic circumstances. These inequalities in health in later life need to be understood in terms of current social, economic, environmental conditions of living, as well as previous experiences and living conditions across the life course that affect the biological processes of ageing.

scholarly journals M56. ASSORTATIVE MATING IN SCHIZOPHRENIA AND BIPOLAR DISORDER: A NATIONWIDE COHORT STUDY EXPLORING THE CHARACTERISTICS OF INDIVIDUALS WHO HAVE CHILDREN BY PARTNERS WITH SCHIZOPHRENIA OR BIPOLAR DISORDER

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S155-S156
Author(s):  
Aja Greve ◽  
Rudolf Uher ◽  
Thomas Damm Als ◽  
Jens Richardt Møllegaard Jepsen ◽  
Erik Lykke Mortensen ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Cohort Study ◽  
Mental Disorders ◽  
Mental Disorder ◽  
Social Functioning ◽  
Assortative Mating ◽  
Processing Speed ◽  
Control Group ◽  
Central Research ◽  
Parent Status

Abstract Background Assortative mating is common in patients with mental disorders, both for specific disorders and across the spectrum of mental disorders. Assortative mating may play a key role in mental disorders because the person with the close relation to an individual with a mental disorder is also likely to have mental disorders, poorer cognitive abilities or lower social functioning, which may further intensify problems for both partners and their offspring. When one parent is ill, the care for the child will often depend on the other parent. Thus, assortative mating will most likely contribute to outcomes in the offspring. Therefore, the objective of this study was to investigate possible diagnoses of a mental illness, cognitive ability and social functioning in individuals who have biological children by partners with schizophrenia or bipolar disorder. Further, we also aimed to explore differences in polygenic risk scores derived from genome-wide association studies for schizophrenia, bipolar disorder, and depression. Methods This study was based on data from The Danish High Risk and Resilience Study - VIA7, a population-based cohort study conducted in Denmark between 2013 and 2016. Subjects were identified through the Danish Civil registration System and the Danish Psychiatric Central Research register. The VIA7 cohort consists of 522 children aged 7 years with parents diagnosed with schizophrenia or bipolar disorder in the Danish registries (index parents) and their partners (non-index parents). This study focuses on the non-index parents (N = 492) without schizophrenia or bipolar disorder in the Danish registries. All participants were interviewed with a diagnostic interview (SCAN 2.0). Main outcomes were intelligence, processing speed, verbal working memory, and social functioning. A linear mixed effect model was applied for each of the outcomes, including parent status (index parent or non-index parent), group (schizophrenia, bipolar disorder, and control), and interaction between parent status and group. Results Non-index parents having children by a partner with schizophrenia or bipolar disorder more often fulfilled the criteria for a mental disorder compared to non-index parents in the control group. Non-index parents having children by a partner with schizophrenia or bipolar disorder had lower levels of social functioning compared to non-index parents in the control group and performed poorer on intelligence and processing speed. Discussion Individuals who have children by partners with schizophrenia or bipolar disorder are more likely to have a mental disorder and to have lower levels of cognitive and social functioning compared to individuals who have children by partners without schizophrenia or bipolar disorder. Assortative mating may have important implications for our understanding of the familial transmission of these disorders. The findings presented in this study should be considered in future genetic research in psychiatry, specifically in the investigation of potential risk factors for children with a parent with schizophrenia or bipolar disorder.

Neurobiology of Older Age Bipolar Disorder

2017 ◽  
pp. 43-56
Author(s):  
Eulogio Eclarinal ◽  
Olusola Ajilore
Keyword(s):  
Bipolar Disorder ◽  
Older Age
Sign in / Sign up

Export Citation Format

Share Document