scholarly journals Telephone‐based Behavioral Activation with Mental Imagery for depression: a pilot randomized clinical trial in isolated older adults during the Covid‐19 pandemic

Author(s):  
Johnny Pellas ◽  
Fritz Renner ◽  
Julie L. Ji ◽  
Mattias Damberg
2021 ◽  
Author(s):  
Johnny Pellas ◽  
Fritz Renner ◽  
Julie Lin Ji ◽  
Mattias Damberg

ObjectivesTo shield vulnerable persons, particularly the eldery, during the Covid-19 pandemic governments around the world have adviced to use social distancing and self-isolation. Social isolation might put older adults at an increased risk for mental health problems such as depression. There is a need for brief, easy-accessible psychological treatments for depressive symptoms that can be delivered remotely. The aim of this study was to investigate the feasibility, acceptability and preliminary efficacy of telephone-delivered Behavioral Activation with Mental Imagery for the treatment of depressive symptoms in individuals 65 years and older living in isolation during the covid-19-pandemic.MethodsIn this open-label pilot randomized clinical trial, N = 41 individuals aged 65 years or older with clinically significant symptoms of depression were randomly assigned to either a Behavioral Activation with Mental Imagery treatment condition, or an Attention-Assessment control condition delivered over the telephone over a four week period.ResultsDepressive symptoms decreased more in the treatment condition compared to the control condition. At post treatment 2 out of 16 participants in the treatment condition met diagnostic criteria for depression compared to 9 out of 13 in the control condition. Most participants in the treatment condition were satisfied with the treatment and few adverse effects were observed.ConclusionsThis pilot study suggests that behavioral activation with mental imagery delivered over the telephone is feasible, acceptable and potentially efficacious for the treatment of depressive symptoms in older individuals living in isolation. Replication in larger samples is needed.


2018 ◽  
Vol 74 (10) ◽  
pp. 1598-1604 ◽  
Author(s):  
Melissa M Markofski ◽  
Kristofer Jennings ◽  
Kyle L Timmerman ◽  
Jared M Dickinson ◽  
Christopher S Fry ◽  
...  

Abstract Background Essential amino acids (EAA) and aerobic exercise (AE) acutely and independently stimulate skeletal muscle protein anabolism in older adults. Objective In this Phase 1, double-blind, placebo-controlled, randomized clinical trial, we determined if chronic EAA supplementation, AE training, or a combination of the two interventions could improve muscle mass and function by stimulating muscle protein synthesis. Methods We phone-screened 971, enrolled 109, and randomized 50 independent, low-active, nonfrail, and nondiabetic older adults (age 72 ± 1 years). We used a 2 × 2 factorial design. The interventions were: daily nutritional supplementation (15 g EAA or placebo) and physical activity (supervised AE training 3 days/week or monitored habitual activity) for 24 weeks. Muscle strength, physical function, body composition, and muscle protein synthesis were measured before and after the 24-week intervention. Results Forty-five subjects completed the 24-week intervention. VO2peak and walking speed increased (p < .05) in both AE groups, irrespective of supplementation type, but muscle strength increased only in the EAA + AE group (p < .05). EAA supplementation acutely increased (p < .05) muscle protein synthesis from basal both before and after the intervention, with a larger increase in the EAA + AE group after the intervention. Total and regional lean body mass did not change significantly with any intervention. Conclusions In nonfrail, independent, healthy older adults AE training increased walking speed and aerobic fitness, and, when combined with EAA supplementation, it also increased muscle strength and EAA-stimulated muscle protein synthesis. These increases occurred without improvements in muscle mass.


2020 ◽  
Vol 133 (7) ◽  
pp. 848-856.e5 ◽  
Author(s):  
Baris Gencer ◽  
Elisavet Moutzouri ◽  
Manuel R. Blum ◽  
Martin Feller ◽  
Tinh-Hai Collet ◽  
...  

2019 ◽  
Vol 84 ◽  
pp. 105789 ◽  
Author(s):  
Elizabeth M. Hudak ◽  
Jennifer Bugos ◽  
Ross Andel ◽  
Jennifer J. Lister ◽  
Ming Ji ◽  
...  

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Wagner Rodrigues Martins ◽  
Marisete Peralta Safons ◽  
Martim Bottaro ◽  
Juscelino Castro Blasczyk ◽  
Leonardo Rios Diniz ◽  
...  

2019 ◽  
Vol Volume 14 ◽  
pp. 1817-1828 ◽  
Author(s):  
Lisa M Roberts ◽  
Byron C Jaeger ◽  
Liliana C Baptista ◽  
Sara A Harper ◽  
Anna K Gardner ◽  
...  

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