Prevalence of major and minor depression in elderly persons with mild cognitive impairment?MADRS factor analysis

2004 ◽  
Vol 19 (12) ◽  
pp. 1168-1172 ◽  
Author(s):  
T. Gabryelewicz ◽  
M. Styczynska ◽  
A. Pfeffer ◽  
B. Wasiak ◽  
A. Barczak ◽  
...  
Keyword(s):  
Factor Analysis ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Elderly Persons ◽  
Minor Depression

Prevalence of minor depression in elderly persons with and without mild cognitive impairment: A systematic review

2014 ◽  
Vol 152-154 ◽  
pp. 28-38 ◽  
Author(s):  
M. Polyakova ◽  
N. Sonnabend ◽  
C. Sander ◽  
R. Mergl ◽  
M.L. Schroeter ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Elderly Persons ◽  
Minor Depression

scholarly journals Frequency and subgroups of neuropsychiatric symptoms in mild cognitive impairment and different stages of dementia in Alzheimer's disease

2017 ◽  
Vol 30 (1) ◽  
pp. 103-113 ◽  
Author(s):  
N. Siafarikas ◽  
G. Selbaek ◽  
T. Fladby ◽  
J. Šaltytė Benth ◽  
E. Auning ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Factor Analysis ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Decline ◽  
Neuropsychiatric Symptoms ◽  
Small Sample ◽  
Psychotic Symptoms ◽  
Cross Sectional

ABSTRACTBackground:Neuropsychiatric symptoms (NPS), such as depression, apathy, agitation, and psychotic symptoms are common in mild cognitive impairment (MCI) and dementia in Alzheimer's disease (AD). Subgroups of NPS have been reported. Yet the relationship of NPS and their subgroups to different stages of cognitive impairment is unclear. Most previous studies are based on small sample sizes and show conflicting results. We sought to examine the frequency of NPS and their subgroups in MCI and different stages of dementia in AD.Methods:This was a cross-sectional study using data from a Norwegian national registry of memory clinics. From a total sample of 4,571 patients, we included those with MCI or AD (MCI 817, mild AD 883, moderate–severe AD 441). To compare variables across groups ANOVA or χ2-test was applied. We used factor analysis of Neuropsychiatric Inventory Questionnaire (NPI-Q) items to identify subgroups of NPS.Results:The frequency of any NPS was 87.2% (AD 91.2%, MCI 79.5%; p < 0.001) and increased with increasing severity of cognitive decline. The most frequent NPS in MCI was depression. Apathy was the most frequent NPS in AD across different stages of severity. The factor analysis identified three subgroups in MCI and mild AD, and a fourth one in moderate–severe AD. We labelled the subgroups “depression,” “agitation,” “psychosis,” and “elation.”Conclusions:The frequency of NPS is high in MCI and AD and increases with the severity of cognitive decline. The subgroups of NPS were relatively consistent from MCI to moderate-severe AD. The subgroup elation appeared only in moderate-severe AD.

scholarly journals Hypothyroidism and Risk of Mild Cognitive Impairment in Elderly Persons

2014 ◽  
Vol 71 (2) ◽  
pp. 201 ◽  
Author(s):  
Ajay K. Parsaik ◽  
Balwinder Singh ◽  
Rosebud O. Roberts ◽  
Shane Pankratz ◽  
Kelly K. Edwards ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Elderly Persons

P1-348: Longitudinal [11C]PIB PET study in healthy elderly persons, patients with mild cognitive impairment, and Alzheimer's disease

2011 ◽  
Vol 7 ◽  
pp. S224-S224 ◽  
Author(s):  
Hitoshi Shinotoh ◽  
Hitoshi Shimada ◽  
Shigeki Hirano ◽  
Noriko Tanaka ◽  
Koichi Sato ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Elderly Persons ◽  
Healthy Elderly

scholarly journals Multiresolution functional brain parcellation in an elderly population with no or mild cognitive impairment

2016 ◽  
Author(s):  
Angela Tam ◽  
Christian Dansereau ◽  
AmanPreet Badhwar ◽  
Pierre Orban ◽  
Sylvie Belleville ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Resting State ◽  
Magnetic Resonance Images ◽  
Regions Of Interest ◽  
Elderly Persons ◽  
Bootstrap Analysis ◽  
File Formats ◽  
Stable Clusters ◽  
The Brain

We present group brain parcellations for clusters generated from resting-state functional magnetic resonance images for 99 cognitively normal elderly persons and 129 patients with mild cognitive impairment, pooled from four independent datasets. The brain parcellations have been registered to both symmetric and asymmetric MNI brain templates and generated using a method called bootstrap analysis of stable clusters (BASC, Bellec et al., 2010). Eight resolutions of clusters were selected using a data-driven method called MSTEPS (Bellec, 2013). We present two variants of these parcellations. One variant contains bihemisphereic parcels (4, 6, 12, 22, 33, 65, 111, and 208 total parcels across eight resolutions). The second variant contains spatially connected regions of interest (ROIs) that span only one hemisphere (10, 17, 30, 51, 77, 199, and 322 total ROIs across eight resolutions). We also present maps illustrating functional connectivity differences between patients and controls for four regions of interest (superior medial frontal cortex, dorsomedial prefrontal cortex, striatum, middle temporal lobe). The brain parcels and associated statistical maps have been publicly released as 3D volumes, available in .mnc and .nii file formats on figshare (http://dx.doi.org/10.6084/m9.figshare.1480461) and on Neurovault (http://neurovault.org/collections/1003/). This dataset was generated as part of the following study: Tam A, Dansereau C, Badhwar A, Orban P, Belleville S, Chertkow H, Dagher A, Hanganu A, Monchi O, Rosa-Neto P, Shmuel A, Wang S, Breitner J, Bellec P for the Alzheimer's Disease Neuroimaging Initiative (2015) Common Effects of Amnestic Mild Cognitive Impairment on Resting-State Connectivity Across Four Independent Studies. Front. Aging Neurosci. 7:242. doi: 10.3389/fnagi.2015.00242
 Finally, the code used to generate this dataset is available on Github (https://github.com/SIMEXP/mcinet).

scholarly journals A Framework for Improving the Interpersonal Relationship of the Elderly with Mild Cognitive Impairment by Using Speaker Recognition and Social Network Platforms

2019 ◽  
Author(s):  
Tan-Hsu Tan ◽  
Fu-Rong Jean ◽  
Chia-Jung Lin ◽  
Tsung-Yu Liu ◽  
Yung-Fa Huang
Keyword(s):  
Cognitive Impairment ◽  
Social Network ◽  
Mild Cognitive Impairment ◽  
Gaussian Mixture Model ◽  
Speaker Recognition ◽  
Interpersonal Relationship ◽  
The Elderly ◽  
Gaussian Mixture ◽  
Elderly Persons ◽  
Relationship Of

This study aims to develop an elderly care system for improving the interpersonal relationship of the elderly with mild cognitive impairment (MCI) by employing the speaker recognition technique and association functionality of social network platforms. Firstly, the speaker recognition units based on the Gaussian Mixture Model (GMM) and Gaussian Mixture Model-Universal Background Model (GMM-UBM) are implemented to identify the visitor via individual input utterance. After the visitor is identified, the proposed system will be linked to the private database and social network platforms to extract the associated message of two parties. Experimental results indicate that the speaker recognition unit based on GMM-UBM achieves the best performance. Finally, five elderly persons are invited to measure the usability of the proposed system. A questionnaire is used to survey the five elderly persons, and the result indicates that the proposed system is highly potentially applicable in improving the interpersonal relationship of the elderly with MCI.

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