GFAP mRNA fluctuates in synchrony with chronic relapsing EAE symptoms in SJL/J mice

Glia ◽  
1995 ◽  
Vol 14 (3) ◽  
pp. 216-224 ◽  
Author(s):  
Avinash Kothavale ◽  
David Di Gregorio ◽  
F. Paul Somera ◽  
Marion E. Smith
Keyword(s):  
Chronic Relapsing Eae

scholarly journals Anti I-A antibody suppresses active encephalomyelitis: treatment model for diseases linked to IR genes.

1983 ◽  
Vol 158 (4) ◽  
pp. 1362-1367 ◽  
Author(s):  
S Sriram ◽  
L Steinman
Keyword(s):  
Autoimmune Disease ◽  
Basic Protein ◽  
Clinical Course ◽  
Treated Group ◽  
Gene Products ◽  
Allergic Encephalomyelitis ◽  
Chronic Relapsing Eae ◽  
Antibody Levels ◽  
Experimental Allergic ◽  
Ir Genes

To test the clinical relevance of monoclonal anti-I-A antibody in autoimmune disease, we investigated the effects of such a therapy in acute and chronic relapsing experimental allergic encephalomyelitis (EAE) by instituting treatment after the onset of paralytic signs and following the clinical course. In chronic relapsing EAE, animals treated with anti-I-As antibody had no mortality and fewer relapses when compared with control animals. Antibody levels to myelin basic protein were lower and histopathology showed milder lesions in the treated group. Similarly, in the acute EAE model, animals treated with anti-I-As antibody showed a dramatic reversal of paralytic signs and a rapid recovery. The mechanisms of action of antibody to IR gene products in autoimmune disease are discussed.

103 TREATMENT OF CHRONIC RELAPSING EAE IN SJL/J MICE WITH CYCLOSPORIN A (CYA)

1984 ◽  
Vol 43 (3) ◽  
pp. 327
Author(s):  
G. B. Schuller-Levis ◽  
P. B. Kozlowski ◽  
H. M. Wisniewski
Keyword(s):  
Cyclosporin A ◽  
Chronic Relapsing Eae

Chronic relapsing EAE time course of neurological symptoms and pathology

1978 ◽  
Vol 43 (1-2) ◽  
pp. 35-42 ◽  
Author(s):  
H. Lassmann ◽  
H. M. Wisniewski
Keyword(s):  
Time Course ◽  
Neurological Symptoms ◽  
Chronic Relapsing Eae

Oligodendrocyte Proliferation and Enhanced CNS Remyelination after Therapeutic Manipulation of Chronic Relapsing EAE

1988 ◽  
Vol 540 (1 Advances in N) ◽  
pp. 712-714 ◽  
Author(s):  
C. S. RAINE ◽  
R. HINTZEN ◽  
U. TRAUGOTT ◽  
G. R. W. MOORE
Keyword(s):  
Chronic Relapsing Eae

Regional and temporal expression patterns of interleukin-10, interleukin-10 receptor and adhesion molecules in the rat spinal cord during chronic relapsing EAE

2003 ◽  
Vol 136 (1-2) ◽  
pp. 94-103 ◽  
Author(s):  
Annemarie Ledeboer ◽  
Anne Wierinckx ◽  
John G.J.M Bol ◽  
Sarah Floris ◽  
Chantal Renardel de Lavalette ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Adhesion Molecules ◽  
Expression Patterns ◽  
Interleukin 10 ◽  
Temporal Expression ◽  
Rat Spinal Cord ◽  
Chronic Relapsing Eae

In vitro NMR micro imaging of the spinal cord of chronic relapsing EAE rats

1994 ◽  
Vol 12 (3) ◽  
pp. 469-475 ◽  
Author(s):  
D. Lanens ◽  
A. Van der Linden ◽  
P.O. Gerrits ◽  
E.J. 's-Gravenmade
Keyword(s):  
Spinal Cord ◽  
Chronic Relapsing Eae
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