Sensory root demyelination: Transforming touch into pain

Glia ◽  
2021 ◽  
Author(s):  
You‐Quan Ding ◽  
Jian‐Guo Qi
Keyword(s):  
Cell Reports ◽  
2020 ◽  
Vol 30 (1) ◽  
pp. 9-17.e3 ◽  
Author(s):  
Evan L. Nichols ◽  
Cody J. Smith

1974 ◽  
Vol 40 (4) ◽  
pp. 504-513 ◽  
Author(s):  
Valmore A. Pelletier ◽  
Dennis A. Poulos ◽  
Richard A. Lende

✓ The composition of the trigeminal root was determined in this study by a combination of electrophysiological recording and stimulation of dissected root fibers in macaques, evaluation of deficits in man after posterior fossa root section, and microdissection in man and macaque. The roots in man and macaque were found anatomically similar. The sensory root contained three distinguishable but overlapping divisions with fibers relating to various peripheral functions and surfaces mixed within each division; no separate region contained fibers of a particular function, and no pattern of somatotopic localization could be determined within a division. The motor root contained sensory proprioceptive fibers, activated by jaw movement, and were found closely intermingled with motor fibers in all fascicles dissected. Accessory fibers (Dandy) were present in all dissections in man and macaque. They contained the same motor and sensory elements as the motor root which they joined. Human partial root sections via the posterior fossa did not exclusively diminish any single sensory modality, and an explanation is offered for the observation that generous surgical sections often result in only slight sensory loss.


Glia ◽  
2004 ◽  
Vol 49 (3) ◽  
pp. 445-450 ◽  
Author(s):  
Michael A. Henry ◽  
Rachael S. Rzasa ◽  
Joshua J. Beeler ◽  
S. Rock Levinson
Keyword(s):  

1952 ◽  
Vol 246 (5) ◽  
pp. 172-176 ◽  
Author(s):  
Charles A. Carton ◽  
Edwin D. Kilbourne

2013 ◽  
Vol 19 (1) ◽  
pp. 9-15
Author(s):  
Th. Dimitropoulou ◽  
C. Dănălache ◽  
P. Bordei ◽  
D.M Iliescu

AbstractThe study of the intracranial traject of the trigeminal nerve was performed through a dissection of 40 human fetuses whose ages ranged between 4 and 9 months. We examined: the apparent origin of the nerve, the traject, stating the length and width of the roots and of the triangular plexus, the antero-posterior width of the trigeminal ganglion and its transverse diameter, measured between the two extremities (horns). The anatomical landmarks were considered left versus right for each fetus and the trigeminal ganglia were studied only in terms of macroscopy: form and relations. We found that the sensory root length increases greatly between the fourth and the fifth month (more than 1 mm), from six to seven months the root length present a stagnation and in the eighth month its increase in length is very significant, about 4 mm, while in the ninth month we also recorded an increase of about 2 mm. The motor root may have two separate fiber bundles, both as cylinders, which can be present from the apparent origin and up to the mandibular nerve; near their origin of the two bundles are separated by nervous tissue. The trigeminal ganglia has, most often, a semilunar aspect, thus justifying its name. Other times it may be irregular, triangular or quadrilateral (rectangular). There are situations when the trigeminal ganglion shows three lobes, each corresponding to one of its three terminal branches.


2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Jana Mrzílková ◽  
Matěj Patzelt ◽  
Pasquale Gallina ◽  
Zdeněk Wurst ◽  
Martin Šeremeta ◽  
...  

Micro-CT imaging is a well-established morphological method for the visualization of animal models. We used ethanol fixation of the mouse brains to perform high-resolution micro-CT scans showing in great details brain grey and white matters. It was possible to identify more than 50 neuroanatomical structures on the 5 selected coronal sections. Among white matter structures, we identified fornix, medial lemniscus, crossed tectospinal pathway, mammillothalamic tract, and the sensory root of the trigeminal ganglion. Among grey matter structures, we identified basal nuclei, habenular complex, thalamic nuclei, amygdala, subparts of hippocampal formation, superior colliculi, Edinger–Westphal nucleus, and others. We suggest that micro-CT of the mouse brain could be used for neurohistological lesions evaluation as an alternative to classical neurohistology because it does not destroy brain tissue.


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