scholarly journals Differential local tissue permissiveness influences the final fate of GPR17-expressing oligodendrocyte precursors in two distinct models of demyelination

Glia ◽  
2018 ◽  
Vol 66 (5) ◽  
pp. 1118-1130 ◽  
Author(s):  
Giusy T. Coppolino ◽  
Davide Marangon ◽  
Camilla Negri ◽  
Gianluca Menichetti ◽  
Marta Fumagalli ◽  
...  
Keyword(s):  
Local Tissue ◽  
Oligodendrocyte Precursors

scholarly journals Metal-on-metal total hip arthroplasty: does increasing modularity affect clinical outcome?

2020 ◽  
pp. 112070002097927
Author(s):  
Kevin C Ilo ◽  
Harry S Hothi ◽  
John A Skinner ◽  
Alister J Hart
Keyword(s):  
Metal Ion ◽  
Hip Prosthesis ◽  
Tissue Reaction ◽  
Bearing Surface ◽  
Adverse Local Tissue Reaction ◽  
Material Loss ◽  
Local Tissue ◽  
Local Tissue Reaction ◽  
Metal On Metal ◽  
Modular Implants

Background: Modularity of metal-on-metal (MoM) implants has come under scrutiny due to concerns regarding additional sources of metal debris. This study is a retrieval analysis of implants from the same manufacturer with the same MoM bearing surface. The difference between the implants was presence or absence of modular junctions. Methods: This is a retrospective study of 31 retrieved implants from 31 patients who received a Conserve Wright Medical MoM hip prosthesis. The 31 implants consisted of 16 resurfacings and 15 implants with modular junctions; 4 conventional THAs and 11 modular-neck THAs. Results: 43% of pre-revision MRI scans performed on resurfacing implants and 91% performed on the modular implants illustrated evidence of an adverse local tissue reaction. There was no difference in pre-revision blood metal ion levels or bearing surface wear between the resurfacings and modular implants. The neck-head tapers of the modular group showed low levels of material loss. However, the neck-stem tapers showed increased severity of corrosion and material loss Conclusions: The modular implants had an increased incidence of adverse local tissue reaction. This could be related to the presence of modular junctions, particular the neck-stem junction which showed increased susceptibly to corrosion

MRI, Retrieval Analysis, and Histologic Evaluation of Adverse Local Tissue Reaction in Metal-on-Polyethylene Total Hip Arthroplasty

2017 ◽  
Vol 32 (5) ◽  
pp. 1647-1653 ◽  
Author(s):  
Scott R. Nodzo ◽  
Christina I. Esposito ◽  
Hollis G. Potter ◽  
Chitranjan S. Ranawat ◽  
Timothy M. Wright ◽  
...  
Keyword(s):  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Tissue Reaction ◽  
Adverse Local Tissue Reaction ◽  
Local Tissue ◽  
Total Hip ◽  
Local Tissue Reaction ◽  
Retrieval Analysis ◽  
Histologic Evaluation

The degradation and local tissue effects of collagen hydrogel and sponge implants in muscle

2017 ◽  
Vol 62 ◽  
pp. 348-354 ◽  
Author(s):  
Tun Yuan ◽  
Yumei Xiao ◽  
Yujiang Fan ◽  
Jie Liang ◽  
Xingdong Zhang
Keyword(s):  
Local Tissue ◽  
Collagen Hydrogel ◽  
Tissue Effects

scholarly journals Langerhans Cells Maintain Local Tissue Tolerance in a Model of Systemic Autoimmune Disease

2015 ◽  
Vol 195 (2) ◽  
pp. 464-476 ◽  
Author(s):  
Jennifer K. King ◽  
Rachael L. Philips ◽  
Anna U. Eriksson ◽  
Peter J. Kim ◽  
Ramesh C. Halder ◽  
...  
Keyword(s):  
Autoimmune Disease ◽  
Langerhans Cells ◽  
Systemic Autoimmune Disease ◽  
Local Tissue
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