scholarly journals Genotype-based matching to correct for population stratification in large-scale case-control genetic association studies

2009 ◽  
Vol 33 (6) ◽  
pp. 508-517 ◽  
Author(s):  
Weihua Guan ◽  
Liming Liang ◽  
Michael Boehnke ◽  
Gonçalo R. Abecasis
Keyword(s):  
Genetic Association ◽  
Population Stratification ◽  
Large Scale ◽  
Association Studies ◽  
Genetic Association Studies ◽  
Case Control

scholarly journals Genetic association studies: Design, analysis and interpretation

2002 ◽  
Vol 3 (2) ◽  
pp. 146-153 ◽  
Author(s):  
Cathryn M. Lewis
Keyword(s):  
Genetic Association ◽  
Transmission Disequilibrium Test ◽  
Population Stratification ◽  
Genetic Model ◽  
Association Studies ◽  
Genetic Association Studies ◽  
Case Control ◽  
Case Control Studies ◽  
Transmission Disequilibrium ◽  
Family Based

Abstract This paper provides a review of the design and analysis of genetic association studies. In case control studies, the different contingency tables and their relationships to the underlying genetic model are defined. Population stratification is discussed, with suggested methods to identify and correct for the effect. The transmission disequilibrium test is provided as an alternative family-based test, which is robust to population stratification. The relative benefits of each analysis are summarised.

scholarly journals Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

2018 ◽  
Vol 50 (9) ◽  
pp. 1335-1341 ◽  
Author(s):  
Wei Zhou ◽  
Jonas B. Nielsen ◽  
Lars G. Fritsche ◽  
Rounak Dey ◽  
Maiken E. Gabrielsen ◽  
...  
Keyword(s):  
Genetic Association ◽  
Large Scale ◽  
Association Studies ◽  
Genetic Association Studies ◽  
Case Control

scholarly journals Assessing the Probability that a Finding Is Genuine for Large-Scale Genetic Association Studies

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0124107 ◽  
Author(s):  
Chia-Ling Kuo ◽  
Olga A. Vsevolozhskaya ◽  
Dmitri V. Zaykin
Keyword(s):  
Genetic Association ◽  
Large Scale ◽  
Association Studies ◽  
Genetic Association Studies

scholarly journals An alternative experimental case–control design for genetic association studies on bovine mastitis

animal ◽  
2017 ◽  
Vol 11 (4) ◽  
pp. 574-579 ◽  
Author(s):  
S. Biffani ◽  
M. Del Corvo ◽  
R. Capoferri ◽  
A. Pedretti ◽  
M. Luini ◽  
...  
Keyword(s):  
Genetic Association ◽  
Association Studies ◽  
Bovine Mastitis ◽  
Genetic Association Studies ◽  
Control Design ◽  
Case Control

Population stratification confounds genetic association studies among Latinos

2005 ◽  
Vol 118 (5) ◽  
pp. 652-664 ◽  
Author(s):  
Shweta Choudhry ◽  
Natasha E. Coyle ◽  
Hua Tang ◽  
Keyan Salari ◽  
Denise Lind ◽  
...  
Keyword(s):  
Genetic Association ◽  
Population Stratification ◽  
Association Studies ◽  
Genetic Association Studies
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