How useful is the fine-scale mapping of complex trait linkage peaks? Evaluating the impact of additional microsatellite genotyping on the posterior probability of linkage

2004 ◽  
Vol 28 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Steven Wiltshire ◽  
Andrew P. Morris ◽  
Mark I. McCarthy ◽  
Lon R. Cardon
Keyword(s):  
Posterior Probability ◽  
Complex Trait ◽  
Fine Scale ◽  
Microsatellite Genotyping ◽  
Posterior Probability Of Linkage ◽  
The Impact ◽  
Fine Scale Mapping

scholarly journals Fine-scale mapping of meiotic recombination in Asians

BMC Genetics ◽  
2013 ◽  
Vol 14 (1) ◽  
pp. 19 ◽  
Author(s):  
Thomas Bleazard ◽  
Young Seok Ju ◽  
Joohon Sung ◽  
Jeong-Sun Seo
Keyword(s):  
Meiotic Recombination ◽  
Fine Scale ◽  
Fine Scale Mapping

Fine‐scale mapping of deep‐sea habitat‐forming species densities reveals taxonomic specific environmental drivers

2021 ◽  
Author(s):  
Jennifer A. Dijkstra ◽  
Kristen Mello ◽  
Derek Sowers ◽  
Mashkoor Malik ◽  
Les Watling ◽  
...  
Keyword(s):  
Deep Sea ◽  
Environmental Drivers ◽  
Fine Scale ◽  
Fine Scale Mapping

scholarly journals Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk

2015 ◽  
Vol 24 (11) ◽  
pp. 1680-1691 ◽  
Author(s):  
Xingyi Guo ◽  
Jirong Long ◽  
Chenjie Zeng ◽  
Kyriaki Michailidou ◽  
Maya Ghoussaini ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Fine Scale ◽  
Fine Scale Mapping

scholarly journals Using geospatial models to map zero-dose children: factors associated with zero-dose vaccination status before and after a mass measles and rubella vaccination campaign

2021 ◽  
Author(s):  
Rohan Arambepola ◽  
Yangyupei Yang ◽  
Kyle Hutchinson ◽  
Francis D Mwansa ◽  
Julie Ann Doherty ◽  
...  
Keyword(s):  
Vaccination Campaign ◽  
Fine Scale ◽  
Healthcare Facilities ◽  
Factors Associated ◽  
Catchment Areas ◽  
Before And After ◽  
Childhood Vaccines ◽  
A Prospective Study ◽  
Vaccination Campaigns ◽  
The Impact

Introduction: Despite gains in global coverage of childhood vaccines, many children remain undervaccinated. Vaccination campaigns also known as Supplemental Immunization Activity (SIA) are commonly conducted to reach those who are undervaccinated. However, reaching these children even during an SIA is challenging. We evaluated the effectiveness of an SIA in reaching zero dose children. Methods: We conducted a prospective study in 10 health center catchment areas in Southern province, Zambia in November 2020. About 2 months before the measles and rubella SIA we developed aerial satellite maps which were then used to enumerate and survey households. Zero dose children were identified during this exercise. After the SIA, households with zero dose children identified before the SIA were targeted for mop up vaccination and to assess if they were vaccinated during the SIA. A Bayesian geospatial model was used to identify factors associated with zero-dose status before the campaign and produce fine-scale prevalence maps. Models were used to identify factors associated with measles zero-dose children reached in the campaign and identify optimal locations for additional vaccination sites. Results: Before the vaccination campaign, 4% of children under 9 months were DTP zero-dose and 17% of children 9-60 months were measles zero-dose. Of the 461 measles zero-dose children identified before the vaccination campaign, 338 (73.3%) were vaccinated during the campaign, 118 (25.6%) were reached by a targeted mop-up activity. The presence of other children in the household, younger age, greater travel time to health facilities, and living between health facility catchment areas were associated with zero-dose status. Mapping zero-dose prevalence revealed substantial heterogeneity, both within and between catchment areas. Several potential locations were identified for additional vaccination sites. Conclusion: Fine-scale variation in zero-dose prevalence and the impact of accessibility to healthcare facilities on vaccination coverage were identified. Geospatial modeling can aid targeted vaccination activities.

scholarly journals The impact of fine-scale turbulence on phytoplankton community structure

2014 ◽  
Vol 4 (1) ◽  
pp. 34-49 ◽  
Author(s):  
Andrew D. Barton ◽  
Ben A. Ward ◽  
Richard G. Williams ◽  
Michael J. Follows
Keyword(s):  
Community Structure ◽  
Phytoplankton Community ◽  
Fine Scale ◽  
Phytoplankton Community Structure ◽  
Scale Turbulence ◽  
The Impact

Influence of fishers’ behaviour on the catchability of surface tuna schools in the Venezuelan purse-seiner fishery in the Caribbean Sea

1999 ◽  
Vol 56 (3) ◽  
pp. 394-406
Author(s):  
Daniel Gaertner ◽  
Mauricio Pagavino ◽  
Jesus Marcano
Keyword(s):  
Environmental Factors ◽  
Daily Activity ◽  
Caribbean Sea ◽  
Catch Rate ◽  
Causal Network ◽  
Fine Scale ◽  
Network Approach ◽  
Logistic Regressions ◽  
The Caribbean ◽  
The Impact

The influence of Venezuelan skippers' behaviour on the catchability of surface tuna schools was modelled using logistic regressions. Data obtained from observers onboard purse seiners indicated that fishers' fine-scale decisions, such as chasing and setting a school, were influenced by (i) the skipper's skill, (ii) the fishing equipment used (e.g., whether a bird radar was used or not), (iii) the features of the tuna school, and (iv) some environmental factors. The connections among the decisions related to the fishing process and these variables were synthesized in a causal network approach. Results clearly showed that schools (i) composed by fishes under 2 kg and (ii) where biomass was lower than 5 metric tons were disregarded by fishers. Because fishers used these thresholds to decide when to set the net, modifications in their behaviour over the years may introduce serious biases in the analysis of any catch rate and abundance relationship. An average daily activity record of a purse seiner shows the proportion of time spent in searching and in setting activities and highlights the impact that the use of new fishing equipment may have on fishing power.

scholarly journals An Impact Location Algorithm for Spacecraft Stiffened Structure Based on Posterior Possibility Correlation

Sensors ◽  
2020 ◽  
Vol 20 (2) ◽  
pp. 368 ◽  
Author(s):  
Lei Qi ◽  
Zhoumo Zeng ◽  
Lichen Sun ◽  
Xiaobo Rui ◽  
Fan Fan ◽  
...  
Keyword(s):  
Posterior Probability ◽  
Cross Correlation ◽  
Bayesian Posterior Probability ◽  
Probability Method ◽  
Stiffened Plate ◽  
Plate Structures ◽  
Impact Location ◽  
Weight Method ◽  
Location Algorithm ◽  
The Impact

In order to ensure the safety of spacecrafts in orbit, impact location is an important part of structural health monitoring systems. In this paper, an impact location algorithm based on posterior probability correlation is proposed to solve the problem, that is, the impact point in the stiffened structure of a spacecraft is difficult to locate. The algorithm combines the Gaussian cross-correlation possibility weight method and the Bayesian posterior probability method. The cross-correlation possibility weight superposition based on grids was used to reduce the dependence of the accuracy of time difference extraction. Gaussian and normalized fitting were used to compensate the reflection, modal transformation, and amplitude attenuation of a stiffened plate. The location result was further optimized by the posterior probability. The proposed algorithm can be applied to the impact source localization of complex stiffened plate structures. The experiment results showed that the average location error can be 2.57 cm with proper sensor network schemes.

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