GAB1‐ABL1 fusions in tumors that have histologic overlap with NTRK ‐ rearranged spindle cell tumors

2021 ◽  
Author(s):  
Florence Choo ◽  
Dinesh Rakheja ◽  
Lara E. Davis ◽  
Monika Davare ◽  
Jason Y. Park ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Spindle Cell Tumors

Three Types of Spindle Cell Tumors of the Pleura

1988 ◽  
Vol 12 (10) ◽  
pp. 747-753 ◽  
Author(s):  
Darryl Carter ◽  
Christopher N. Otis
Keyword(s):  
Spindle Cell ◽  
Spindle Cell Tumors

Solitary Fibrous Tumor of the Prostate

2001 ◽  
Vol 125 (2) ◽  
pp. 274-277
Author(s):  
Michael R. Pins ◽  
Steven C. Campbell ◽  
William B. Laskin ◽  
Karen Steinbronn ◽  
Daniel P. Dalton
Keyword(s):  
Mitotic Activity ◽  
Solitary Fibrous Tumor ◽  
Growth Pattern ◽  
Spindle Cell ◽  
Cytologic Atypia ◽  
Diffuse Growth ◽  
High Mitotic Activity ◽  
Spindle Cell Tumors ◽  
Fibrous Tumor

Abstract We report 2 cases of solitary fibrous tumor of the prostate. Histologically, both tumors demonstrated a multipatterned architecture with varying degrees of collagenization and hemangiopericytoma-like foci, and both were composed of CD34-immunopositive spindled cells that insinuated themselves between strips of collagen. The tumor in case 1 was well circumscribed and showed minimal mitotic activity or pleomorphism, whereas the tumor in case 2 was more cellular, less collagenous, had a more diffuse growth pattern, and exhibited cytologic atypia and high mitotic activity. Prostatic solitary fibrous tumor must be distinguished from other spindle cell tumors reported to occur in the prostate. To our knowledge, these cases represent only the fifth and sixth reported cases of prostatic solitary fibrous tumor.

Spindle Cell Tumors of Adults

2013 ◽  
pp. 13-93
Author(s):  
Adrián Mariño-Enríquez ◽  
Louis Guillou ◽  
Jason L. Hornick
Keyword(s):  
Spindle Cell ◽  
Spindle Cell Tumors

Spindle cell tumors of bone and soft tissue in infants and children

2013 ◽  
pp. 23-40
Author(s):  
Lester J. Layfield ◽  
Carlos W. Bedrossian ◽  
Julia R. Crim ◽  
Lucio Palombini
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Infants And Children ◽  
Tumors Of Bone ◽  
Spindle Cell Tumors ◽  
In Infants And Children

SMOOTH AND SKELETAL MUSCLE MYOSINS IN SPINDLE CELL TUMORS OF SOFT TISSUE

1985 ◽  
Vol 35 (1) ◽  
pp. 125-136 ◽  
Author(s):  
Takashi Saku ◽  
Nobuo Tsuda ◽  
Masanobu Anami ◽  
Haruo Okabe
Keyword(s):  
Skeletal Muscle ◽  
Soft Tissue ◽  
Spindle Cell ◽  
Spindle Cell Tumors

scholarly journals Immunohistochemical analysis of pigment cell tumors in two cyprinid species

2019 ◽  
Vol 31 (5) ◽  
pp. 788-791
Author(s):  
Wesley C. Siniard ◽  
Matthew F. Sheley ◽  
Brittany N. Stevens ◽  
Christine A. Parker-Graham ◽  
Melissa A. Roy ◽  
...  
Keyword(s):  
Internal Control ◽  
Spindle Cell ◽  
Pigment Cell ◽  
Immunohistochemical Analysis ◽  
Pigment Cells ◽  
Semiquantitative Analysis ◽  
Cellular Origin ◽  
Immunohistochemical Assay ◽  
Cyprinid Species ◽  
Spindle Cell Tumors

Pigment cell tumors, also known as chromatophoromas, are cutaneous spindle cell neoplasms originating from pigment cells (chromatophores) in the dermis of teleosts, amphibians, and reptiles. Chromatophoromas share similar histologic morphology to other spindle cell tumors and are not always pigmented. Therefore, immunohistochemical analysis may be useful in distinguishing these neoplasms from tumors of other cellular origin when poorly pigmented. We performed 3 immunohistochemistry assays (PNL-2, melan A, and SOX10) on 8 cutaneous neoplasms from 8 teleosts diagnosed as chromatophoromas based on histologic morphology. Semiquantitative analysis of immunoreactivity was evaluated on each immunohistochemical assay using a 0–3 scale. PNL-2 exhibited mild-to-moderate (1 or 2) immunoreactivity in 7 of the cases, and resident chromatophores (internal control) were also immunoreactive in these cases. Melan A exhibited mild-to-moderate (1 or 2) immunoreactivity in 4 cases (and with resident chromatophores in these cases); SOX10 was not immunoreactive in any cases. Our results indicate that PNL-2 may be a useful marker in teleosts to distinguish tumors of chromatophore origin. Melan A could also be useful, but appears to be less sensitive, and SOX10 is likely not a useful marker for these neoplasms in teleosts.

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