Dedifferentiated secretory breast carcinoma with fibrosarcomatous features harboring an ETV6‐NTRK3 fusion in both components

2020 ◽  
Author(s):  
Jin Xu ◽  
Paul Weisman
Keyword(s):  
Breast Carcinoma ◽  
Secretory Breast Carcinoma

scholarly journals Successful Targeted Therapy of Refractory Pediatric ETV6-NTRK3 Fusion-Positive Secretory Breast Carcinoma

2017 ◽  
pp. 1-8 ◽  
Author(s):  
Neerav Shukla ◽  
Stephen S. Roberts ◽  
Mollah O. Baki ◽  
Qazi Mushtaq ◽  
Paul E. Goss ◽  
...  
Keyword(s):  
Targeted Therapy ◽  
Breast Carcinoma ◽  
Secretory Breast Carcinoma

Secretory Breast Carcinoma in a Man

1988 ◽  
Vol 12 (2) ◽  
pp. 150-154 ◽  
Author(s):  
Joel A. Roth ◽  
Carolyn Discafani ◽  
Miriam OʼMalley
Keyword(s):  
Breast Carcinoma ◽  
Secretory Breast Carcinoma

scholarly journals Secretory breast carcinoma in a female adult with liver metastsis: a case report and literature review

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Jing Lian ◽  
Li-Xia Wang ◽  
Jiang-hong Guo ◽  
Peng Bu ◽  
Yan-feng Xi ◽  
...  
Keyword(s):  
Liver Metastasis ◽  
Breast Carcinoma ◽  
Poor Prognosis ◽  
Hormone Receptors ◽  
Fatal Outcome ◽  
Radical Mastectomy ◽  
Distant Metastases ◽  
Left Breast ◽  
Secretory Breast Carcinoma

Abstract Background Secretory breast carcinoma is an uncommon subset of breast cancer that usually has a favorable outcome. Although initially described in children, it also occurs in adults where it may metastasize, possibly resulting in death. To date, only 20 cases of secretory breast carcinoma with distant metastases have been described. Case presentation A 42-year-old female presented with liver metastasis after modified radical mastectomy of the left breast in 2008 at 34 years of age. The liver metastasis was morphologically similar to the primary tumor. Pan-TRK and Fluorescence in situ hybridization showed a rearrangement in the ETV6 gene. She subsequently underwent adjuvant chemotherapy with a fatal outcome. Conclusions Although secretory breast carcinoma is usually associated with favorable outcomes, our study and reviews provide a novel insight into the genetic spectrum and treatment of secretory breast carcinoma showing reduced expression of hormone receptors, abnormal genomic profiles, and possible poor prognosis. Targeted therapy may curb clinically aggressive cases. Additional molecular investigations are needed to determine the links between specific mutations and poor prognosis.

Secretory breast carcinoma: A report of two cases

2019 ◽  
Vol 32 (1) ◽  
pp. 32-36
Author(s):  
Guillermo G. Peralta Castillo ◽  
Ricardo Cavazos García ◽  
Verónica Bautista Piña ◽  
Jorge Alberto Salazar Andrade ◽  
Jorge Enrique Monges Jones ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Secretory Breast Carcinoma

scholarly journals Secretory breast carcinoma: A report of three cases and a review of the literature

2014 ◽  
Vol 8 (2) ◽  
pp. 683-686 ◽  
Author(s):  
SEUNG GEUN LEE ◽  
SEUNG PIL JUNG ◽  
HYE YOON LEE ◽  
SINILL KIM ◽  
HOON YUB KIM ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Review Of The Literature ◽  
Secretory Breast Carcinoma

scholarly journals Secretory breast carcinoma: a clinicopathological and immunophenotypic study of 15 cases with a review of the literature

2011 ◽  
Vol 25 (4) ◽  
pp. 567-575 ◽  
Author(s):  
Dali Li ◽  
Xiuying Xiao ◽  
Wentao Yang ◽  
Ruohong Shui ◽  
Xiaoyu Tu ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Review Of The Literature ◽  
Secretory Breast Carcinoma

SECRETORY BREAST CARCINOMA IN A 9-YEAR-OLD BOY

2000 ◽  
Vol 70 (2) ◽  
pp. 144-146 ◽  
Author(s):  
J. Titus ◽  
R. W. Sillar ◽  
L. E. Fenton
Keyword(s):  
Breast Carcinoma ◽  
Secretory Breast Carcinoma

Secretory breast carcinoma in a 6-year-old girl: mastectomy with sentinel lymph node dissection

2015 ◽  
Vol 31 (7) ◽  
pp. 677-681 ◽  
Author(s):  
Tutku Soyer ◽  
İnci Yaman Bajin ◽  
Diclehan Orhan ◽  
Bilgehan Yalçin ◽  
Pinar Özgen Kiratli ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Breast Carcinoma ◽  
Lymph Node Dissection ◽  
Sentinel Lymph Node Dissection ◽  
Node Dissection ◽  
Secretory Breast Carcinoma

ETV6 Disruption Does Not Predict Indolent Clinical Behavior in Secretory Breast Carcinoma

2012 ◽  
Vol 18 (6) ◽  
pp. 604-606 ◽  
Author(s):  
Mabel Wong ◽  
Ana Richelia Jara-Lazaro ◽  
Raymond Chee Hui Ng ◽  
Alvin Soon Tiong Lim ◽  
Poh Yian Cheok ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Clinical Behavior ◽  
Secretory Breast Carcinoma
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