scholarly journals Comprehensive molecular cytogenetic characterization of cervical cancer cell lines

2003 ◽  
Vol 36 (3) ◽  
pp. 233-241 ◽  
Author(s):  
Charles P. Harris ◽  
Xin Yan Lu ◽  
Gopeshwar Narayan ◽  
Bhuvanesh Singh ◽  
Vundavalli V. V. S. Murty ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Cervical Cancer Cell ◽  
Molecular Cytogenetic ◽  
Cytogenetic Characterization

scholarly journals Molecular cytogenetic characterization of two murine cancer cell lines derived from salivary gland

2018 ◽  
Vol 63 (4) ◽  
pp. 243-255 ◽  
Author(s):  
Ralf Steinacker ◽  
◽  
Thomas Liehr ◽  
Nadezda Kosyakova ◽  
Martina Rincic ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Molecular Cytogenetic ◽  
Cytogenetic Characterization

scholarly journals Definitive molecular cytogenetic characterization of 15 colorectal cancer cell lines

2009 ◽  
pp. NA-NA ◽  
Author(s):  
Turid Knutsen ◽  
Hesed M. Padilla-Nash ◽  
Danny Wangsa ◽  
Linda Barenboim-Stapleton ◽  
Jordi Camps ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Colorectal Cancer Cell ◽  
Molecular Cytogenetic ◽  
Colorectal Cancer Cell Lines ◽  
Cytogenetic Characterization

scholarly journals Molecular Cytogenetic Characterization of Two Murine Colorectal Cancer Cell Lines

OBM Genetics ◽  
2018 ◽  
Vol 2 (3) ◽  
pp. 1-1 ◽  
Author(s):  
Hans Rhode ◽  
◽  
Thomas Liehr ◽  
Nadezda Kosyakova ◽  
Martina Rinčić ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Colorectal Cancer Cell ◽  
Molecular Cytogenetic ◽  
Colorectal Cancer Cell Lines ◽  
Cytogenetic Characterization

Molecular cytogenetic characterization of pancreas cancer cell lines reveals high complexity chromosomal alterations

2007 ◽  
Vol 118 (2-4) ◽  
pp. 148-156 ◽  
Author(s):  
C.A. Griffin ◽  
L. Morsberger ◽  
A.L. Hawkins ◽  
M. Haddadin ◽  
A. Patel ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Pancreas Cancer ◽  
Cancer Cell Lines ◽  
High Complexity ◽  
Chromosomal Alterations ◽  
Molecular Cytogenetic ◽  
Cytogenetic Characterization

Synthesis and characterization of tributyltin derivatives from 4-oxo-4-(arylamino)butanoic acids and theirin vitrobiological activity against cervical cancer cell lines

2014 ◽  
Vol 28 (12) ◽  
pp. 884-891 ◽  
Author(s):  
Irma Rojas-Oviedo ◽  
Carlos Camacho-Camacho ◽  
Luis Sánchez-Sánchez ◽  
Jorge Cárdenas ◽  
Hugo López-Muñoz ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Cervical Cancer Cell ◽  
Synthesis And Characterization

Sensitization of cervical cancer cell lines to low-dose radiation by retinoic acid does not require functional p53

2005 ◽  
Vol 97 (1) ◽  
pp. 142-150 ◽  
Author(s):  
Todd D. Tillmanns ◽  
Scott A. Kamelle ◽  
Suresh Guruswamy ◽  
Natalie S. Gould ◽  
Teresa L. Rutledge ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Retinoic Acid ◽  
Cell Lines ◽  
Cancer Cell ◽  
Low Dose ◽  
Cancer Cell Lines ◽  
Cervical Cancer Cell ◽  
Low Dose Radiation ◽  
Dose Radiation

scholarly journals Adenoviral Vectors Armed with PAPILLOMAVIRUs Oncogene Specific CRISPR/Cas9 Kill Human-Papillomavirus-Induced Cervical Cancer Cells

Cancers ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1934 ◽  
Author(s):  
Eric Ehrke-Schulz ◽  
Sonja Heinemann ◽  
Lukas Schulte ◽  
Maren Schiwon ◽  
Anja Ehrhardt
Keyword(s):  
Cervical Cancer ◽  
Cancer Cells ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cancer Cell Lines ◽  
Adenoviral Vectors ◽  
Human Papillomaviruses ◽  
Cervical Cancer Cell ◽  
Adenoviral Delivery ◽  
Cervical Cancer Cells

Human papillomaviruses (HPV) cause malignant epithelial cancers including cervical carcinoma, non-melanoma skin and head and neck cancer. They drive tumor development through the expression of their oncoproteins E6 and E7. Designer nucleases were shown to be efficient to specifically destroy HPV16 and HPV18 oncogenes to induce cell cycle arrest and apoptosis. Here, we used high-capacity adenoviral vectors (HCAdVs) expressing the complete CRISPR/Cas9 machinery specific for HPV18-E6 or HPV16-E6. Cervical cancer cell lines SiHa and CaSki containing HPV16 and HeLa cells containing HPV18 genomes integrated into the cellular genome, as well as HPV-negative cancer cells were transduced with HPV-type-specific CRISPR-HCAdV. Upon adenoviral delivery, the expression of HPV-type-specific CRISPR/Cas9 resulted in decreased cell viability of HPV-positive cervical cancer cell lines, whereas HPV-negative cells were unaffected. Transduced cervical cancer cells showed increased apoptosis induction and decreased proliferation compared to untreated or HPV negative control cells. This suggests that HCAdV can serve as HPV-specific cancer gene therapeutic agents when armed with HPV-type-specific CRISPR/Cas9. Based on the versatility of the CRISPR/Cas9 system, we anticipate that our approach can contribute to personalized treatment options specific for the respective HPV type present in each individual tumor.

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