scholarly journals Protective effects of a triple-fermented barley extract (FBe) against HCl/EtOH-induced gastric mucosa damage in mice

2018 ◽  
Vol 6 (8) ◽  
pp. 2036-2046 ◽  
Author(s):  
Jong-Min Lim ◽  
Chang-Hyun Song ◽  
Su-Jin Park ◽  
Dong-Chan Park ◽  
Hyung-Rae Cho ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Protective Effects ◽  
Gastric Mucosa Damage

Effect of fulvic acid on gastric mucosa damage caused by chronic water avoidance stress

2021 ◽  
pp. 1-8
Author(s):  
Sezen Gizem Gurel ◽  
Ibrahim Sogut ◽  
Canan Hurdag ◽  
Ali Gurel ◽  
Ahmet Tutar ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Fulvic Acid ◽  
Gastric Mucosa Damage

scholarly journals Mechaqnism of protective effects of Ouren-Gedoku-To and San'ou-Syashin-To on the gastric mucosa.

1991 ◽  
Vol 98 (4) ◽  
pp. 319-325 ◽  
Author(s):  
Toshiaki SUENAGA ◽  
Toshio SHIRAKAWA ◽  
Nobue HARADA ◽  
Chie TAO ◽  
Masashi YAMASAKI ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Protective Effects

Combined but not single administration of vitamin C and l-carnitine ameliorates cisplatin-induced gastric mucosa damage in male rats

2018 ◽  
Vol 96 (8) ◽  
pp. 830-838 ◽  
Author(s):  
Modinat Adebukola Adefisayo ◽  
Wale Johnson Adeyemi ◽  
Quadri Kunle Alabi
Keyword(s):  
Gastric Mucosa ◽  
Adverse Effects ◽  
Vitamin C ◽  
Clinical Symptoms ◽  
Treated Group ◽  
Male Rats ◽  
Control Group ◽  
Inflammatory Infiltration ◽  
Inflammatory Reactions ◽  
Gastric Mucosa Damage

Although cisplatin is a potent anticancer drug, it instigates oxidative and pro-inflammatory reactions that pose significant and distressing clinical symptoms. Therefore, this study investigated the effects of vitamin C and (or) l-carnitine on cisplatin-induced gastric mucosa damage in rat. The rats were allocated into 6 groups (n = 5). The control group received distilled water, while the treatment groups received cisplatin alone (CIP), or cisplatin with vitamin C, l-carnitine, or their combination. Cisplatin caused disruption of the gastric mucosa histoarchitecture and altered the mucus barrier function. Moreover, the stomach tissue of the CIP-treated group showed increased levels of oxidative stress markers (malondialdehyde and H2O2) and decreased activities of antioxidant (superoxide dismutase, glutathione peroxidase, catalase, glutathione S-transferase) and non-antioxidant (reduced glutathione) enzymes. These deleterious events were accompanied with significant increases in pro-inflammatory cytokines and inflammatory infiltration markers, myeloperoxidase and inducible nitric oxide synthase. However, the administration of both vitamin C and l-carnitine, and not either of the two showed additive effects in attenuating the adverse effects of cisplatin. The histological results agreed with the biochemical assays. The study concluded that the combined administration of vitamin C and l-carnitine, but not the single therapy, could prevent the adverse effects of cisplatin on gastric tissue.

Protection by Liquorice in Alcohol Induced Gastric Mucosa Damage

2009 ◽  
Vol 8 (10) ◽  
pp. 1532-1536 ◽  
Author(s):  
A.E. Ligha ◽  
H.B. Fawehinmi
Keyword(s):  
Gastric Mucosa ◽  
Gastric Mucosa Damage

To the noradrenergic component of the mechanisms of stress-limiting and healing effects of dalargin

2016 ◽  
Vol 14 (4) ◽  
pp. 61-66
Author(s):  
Oleg N Zabrodin
Keyword(s):  
Gastric Mucosa ◽  
Bone Fractures ◽  
Reparative Regeneration ◽  
Synthetic Analogue ◽  
Protective Effects ◽  
Pharmacological Agents ◽  
Adrenal System ◽  
Liver And Pancreas ◽  
Sympathetic Nervous ◽  
Neurogenic Lesions

The article presents the facts of the stress-limiting and healing effects of a synthetic analogue of leucine-enkefalin dalargin (D), the analysis of literature data of the modulating effects of D on the activity of sympathetic-adrenal system (SAS) in various extraordinary influences. D prevents: hyperactivity of SAS, associated development of dystrophic-destructive changes in the organs (heart, gastric mucosa, duodenum) and the exhaustion of catecholamine’s (CA) depot in the sympathetic endings. It is noted that similar protective effects against the development of neurogenic lesions in the organs (heart, gastric mucosa, liver and pancreas) have pharmacological agents with antiadrenergic component of actions (gangliolitiks and sympatholitiks, alpha - and beta-adrenoblokers). In the article mapped the healing effects of D in relation to the gastric mucosa destructions, skin incisional wounds, bone fractures with the ability of the sympathetic nervous system to stimulate reparative regeneration in various tissues (cornea. gastric mucosa, myocardium, liver, sympathetic reinnervation). It is concluded that the stress-limiting and healing effects of D have a noradrenergic component associated with modulating effect of D on the activity of SAS. In the conditions of extraordinary influences D suppresses SAS hyperactivity, keeping the reserves of CA in the sympathetic endings. In the implementation of reparative regeneration of tissues CA, and primarily sympathetic mediator noradrenalin, promote healing of damaged organs and tissues.

Protective effects of prostaglandins in the isolated gastric mucosa of the eel, Anguilla anguilla

2000 ◽  
Vol 170 (5-6) ◽  
pp. 357-363 ◽  
Author(s):  
C. Faggio ◽  
M. G. Denaro ◽  
M. G. Lionetto ◽  
F. Trischitta
Keyword(s):  
Gastric Mucosa ◽  
Anguilla Anguilla ◽  
Protective Effects

The hypothalamus–pituitary–adrenal axis does not influence the protective effects of nociceptin/orphanin FQ on the rat gastric mucosa

2009 ◽  
Vol 154 (1-3) ◽  
pp. 32-38 ◽  
Author(s):  
Daniela Grandi ◽  
Elvira Solenghi ◽  
Remo Guerrini ◽  
Maria Broccardo ◽  
Simona Agostini ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Protective Effects ◽  
Orphanin Fq ◽  
Adrenal Axis ◽  
Rat Gastric Mucosa ◽  
Hypothalamus Pituitary Adrenal Axis ◽  
Pituitary Adrenal Axis
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