scholarly journals Konjac Glucomannan from Amorphophallus konjac enhances immunocompetence of the cyclophosphamide‐induced immunosuppressed mice

2020 ◽  
Author(s):  
Jiajia Dai ◽  
Jian Chen ◽  
Jun Qi ◽  
Mengru Ding ◽  
Wei Liu ◽  
...  
Keyword(s):  
Konjac Glucomannan ◽  
Amorphophallus Konjac ◽  
Immunosuppressed Mice

Tracing the Evolution and Economic Potential of Konjac Glucomannan in Amorphophallus species (Araceae) using Molecular Phylogeny and RAPD Markers

Phytotaxa ◽  
2016 ◽  
Vol 282 (2) ◽  
pp. 81 ◽  
Author(s):  
ORACHORN MEKKERDCHOO ◽  
CHALEEDA BOROMPICHAICHARTKUL ◽  
ALLISON PERRIGO ◽  
GEORGE SRZEDNICKI ◽  
CHEUNJIT PRAKITCHAIWATTANA ◽  
...  
Keyword(s):  
Rapd Markers ◽  
Genetic Relationships ◽  
Its Region ◽  
Pharmaceutical Products ◽  
Konjac Glucomannan ◽  
Closely Related Species ◽  
Dna Variation ◽  
Amorphophallus Konjac ◽  
Genome Wide ◽  
Present Understanding

The genus Amorphophallus is an economically important taxon that is abundant in Old World tropical forests (Asia, Oceania and Africa). It includes many species that are used with increasing frequency as a source of food and pharmaceutical products worldwide. Amorphophallus konjac is an important economic crop and has been used widely in China and Japan for commercial konjac glucomannan (KGM) production. However, the species’ range does not extend to Thailand, where other closely related species may be more suitable for commercial KGM production. Present understanding of genetic relationships among Thai Amorphophallus species is still limited, and the connection between evolutionary history and KGM content is unknown. Here, the genetic relationships among various accessions of Amorphophallus spp. collected in Thailand are investigated using the chloroplast trnL-trnF spacer, nuclear ribosomal internal transcribed spacer (ITS) region and the second intron of LEAFY (FLint2) together with genome-wide DNA variation analysis, Randomly Amplified Polymorphic DNA (RAPD) technique. RAPD primers are also developed to quickly and efficiently identify species producing high levels of KGM. This study finds that two monophyletic clades include high KGM content species. RAPD analyses indicate that primer AC-10 generates specific bands identifying species belonging only to the high and medium KGM content clades.  These primers can be used as a screening tool for economical species, aiming at improving the industrial production of KGM in Thailand and the world.

scholarly journals Effect of Konjac Glucomannan (KGM) on the Reconstitution of the Dermal Environment against UVB-Induced Condition

Nutrients ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2779
Author(s):  
Kyung Ho Choi ◽  
Sung Tae Kim ◽  
Bum Ho Bin ◽  
Phil June Park
Keyword(s):  
Quantitative Polymerase Chain Reaction ◽  
Human Fibroblasts ◽  
Konjac Glucomannan ◽  
The Body ◽  
Skin Damage ◽  
Related Factors ◽  
Young Cell ◽  
Amorphophallus Konjac ◽  
Protein Levels ◽  
Age Related

Skin layers serve as a barrier against unexpected critical changes in the body due to environmental factors. Excessive ultraviolet (UV) B exposure increases the levels of age-related factors, leading to senescent cells and damaged skin tissues. Widely used as a dietary supplement, konjac (Amorphophallus konjac) glucomannan (KGM) has shown skin regeneration potential in patch or sheet form with anti-inflammatory or immunosuppressive effects. However, the ability of KGM to reconstitute senescent/damaged skin following UV radiation has not been explored. Here, we demonstrate that KGM alleviates skin damage by increasing the proportion of young cell populations in UVB-exposed senescent human epidermal primary melanocytes. Young cell numbers increased depending on KGM dosage, but the senescent cells were not removed. Real-time quantitative polymerase chain reaction (RT-qPCR) and Western blot analysis showed that mRNA and protein levels of age- and pigmentation-related factors decreased in a manner dependent on the rate at which new cells were generated. Moreover, an analysis of mRNA and protein levels indicated that KGM facilitated youth by increasing cell proliferation in UVB-damaged human fibroblasts. Thus, KGM is a highly effective natural agent for maintaining skin homeostasis by promoting the reconstitution of the dermal environment against UVB-induced acute senescence or skin damage.

scholarly journals Needleless electrospun polyacrylonitrile/konjac glucomannan nanofiber mats

2020 ◽  
Vol 15 ◽  
pp. 155892502096480
Author(s):  
Al Mamun ◽  
Marah Trabelsi ◽  
Michaela Klöcker ◽  
Jan Lukas Storck ◽  
Robin Böttjer ◽  
...  
Keyword(s):  
Raw Materials ◽  
Average Diameter ◽  
Konjac Glucomannan ◽  
Raw Material ◽  
Oxidative Stabilization ◽  
Carbon Nanocomposites ◽  
Amorphophallus Konjac ◽  
Wide Range ◽  
The Cost ◽  
Nanofiber Mats

In this study we report for the first time about the preparation of polyacrilontrile (PAN)/konjac glucomannan (KGM) nanofiber mats, needleless electrospinning from the low-toxic solvent dimethyl sulfoxide (DMSO) and the formation of carbon nanocomposites. Konjac glucomannan is a biopolymer and renewable, environmentally friendly raw material and a well-known polysaccharide, which is non-toxic and biocompatible material and is extracted from the Amorphophallus konjac plant. The addition of poloxamer in electrospinning PAN/KGM solution resulted in the reduction of membrane areas and decrease of beads in nanofibers. The concentration of 1.5% or 0.5% of konjac glucomannan in PAN/KGM nanofiber mats was not detected to affect the morphology of the nanofiber mats. The PAN/KGM nanofiber mats received oxidative stabilization and subsequent carbonization. It could be observed that after the oxidative stabilization process the average diameter of PAN/KGM nanofibers increased and after carbonization decreased compared to stabilized nanofibers. Alternative renewable raw materials such as KGM electrospun with synthetic polymers offer the possibility to reduce the environmental impact and are the alternative to new technical materials and lowers the cost of carbon materials. The combination of PAN with konjac glucomannan and the properties of both polymers open up a wide range of applications for the PAN/KGM nanofiber mats and carbon nanocomposites produced in this study, for example, for pharmaceutical and biomedical applications, as absorbents for the removal of pollutants in wastewater and as filter media for air purification, as well as for optical and chemical sensors.

Methodologies for the extraction and analysis of konjac glucomannan from corms of Amorphophallus konjac K. Koch

2012 ◽  
Vol 87 (3) ◽  
pp. 2202-2210 ◽  
Author(s):  
Melinda Chua ◽  
Kelvin Chan ◽  
Trevor J. Hocking ◽  
Peter A. Williams ◽  
Christopher J. Perry ◽  
...  
Keyword(s):  
Konjac Glucomannan ◽  
Amorphophallus Konjac

Biocontrol effect of Lysobacter antibioticus 06-4 on soft rot pathogen of Amorphophallus konjac its mechanism

2011 ◽  
Vol 37 (3) ◽  
pp. 286-289 ◽  
Author(s):  
Li-hui ZHANG ◽  
Yong-ji WANG ◽  
Lin LIAO ◽  
Guang-hai JI
Keyword(s):  
Soft Rot ◽  
Amorphophallus Konjac
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