scholarly journals Comparative study of the effects of diosmin and diosmetin on fat accumulation, dyslipidemia, and glucose intolerance in mice fed a high‐fat high‐sucrose diet

2020 ◽  
Vol 8 (11) ◽  
pp. 5976-5984
Author(s):  
Sangwon Chung ◽  
Hyo‐Jin Kim ◽  
Hyo‐Kyoung Choi ◽  
Jae Ho Park ◽  
Jin‐Taek Hwang
Keyword(s):  
Comparative Study ◽  
Glucose Intolerance ◽  
High Fat ◽  
Fat Accumulation ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
High Sucrose

scholarly journals Blueberry Leaf Polyphenols Prevent Body Fat Accumulation in Mice Fed High-fat, High-sucrose Diet

2019 ◽  
Vol 68 (5) ◽  
pp. 471-479 ◽  
Author(s):  
Kento Fujii ◽  
Yuma Ota ◽  
Kazuo Nishiyama ◽  
Hisato Kunitake ◽  
Yumi Yamasaki ◽  
...  
Keyword(s):  
Body Fat ◽  
High Fat ◽  
Fat Accumulation ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
High Sucrose

scholarly journals Male and Female Rats Have Different Physiological Response to High-Fat High-Sucrose Diet but Similar Myocardial Sensitivity to Ischemia-Reperfusion Injury

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 2914
Author(s):  
Natacha Fourny ◽  
Carole Lan ◽  
Monique Bernard ◽  
Martine Desrois
Keyword(s):  
Reperfusion Injury ◽  
Glucose Intolerance ◽  
Physiological Response ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
High Fat ◽  
Male And Female ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
High Sucrose

Prediabetes is a strong predictor of type 2 diabetes and its associated cardiovascular complications, but few studies explore sexual dimorphism in this context. Here, we aim to determine whether sex influences physiological response to high-fat high-sucrose diet (HFS) and myocardial tolerance to ischemia-reperfusion injury. Male and female Wistar rats were subjected to standard (CTRL) or HFS diet for 5 months. Then, ex-vivo experiments on isolated perfused heart model were performed to evaluate tolerance to ischemia-reperfusion injury. HFS diet induced fasting hyperglycemia and increased body fat percent to a similar level in both sexes. However, glucose intolerance was more pronounced in female HFS. Cholesterol was increased only in female while male displayed higher level of plasmatic leptin. We observed increased heart weight to tibia length ratio only in males, but we showed a similar decrease in tolerance to ischemia-reperfusion injury in female and male HFS compared with respective controls, characterized by impaired cardiac function, energy metabolism and coronary flow during reperfusion. In conclusion, as soon as glucose intolerance and hyperglycemia develop, we observe higher sensitivity of hearts to ischemia-reperfusion injury without difference between males and females.

scholarly journals Caffeine, but not other phytochemicals, in mate tea (Ilex paraguariensis St. Hilaire) attenuates high-fat-high-sucrose-diet-driven lipogenesis and body fat accumulation

2020 ◽  
Vol 64 ◽  
pp. 103646 ◽  
Author(s):  
Fatima J. Zapata ◽  
Miguel Rebollo-Hernanz ◽  
Jan E. Novakofski ◽  
Manabu T. Nakamura ◽  
Elvira Gonzalez de Mejia
Keyword(s):  
Body Fat ◽  
Ilex Paraguariensis ◽  
High Fat ◽  
Fat Accumulation ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
Mate Tea ◽  
High Sucrose

scholarly journals Anacardic acid mitigates liver fat accumulation and impaired glucose tolerance in mice fed a high‐fat and high‐sucrose diet

2020 ◽  
Vol 8 (2) ◽  
pp. 796-804 ◽  
Author(s):  
Sangwon Chung ◽  
Eun Ju Shin ◽  
Hyo‐Kyoung Choi ◽  
Jae Ho Park ◽  
Jin‐Taek Hwang
Keyword(s):  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Anacardic Acid ◽  
Liver Fat ◽  
High Fat ◽  
Fat Accumulation ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
High Sucrose

scholarly journals Dietary diacylglycerol suppresses high fat and high sucrose diet-induced body fat accumulation in C57BL/6J mice

2001 ◽  
Vol 42 (3) ◽  
pp. 372-378 ◽  
Author(s):  
Takatoshi Murase ◽  
Tomohito Mizuno ◽  
Toshiko Omachi ◽  
Kouji Onizawa ◽  
Yumiko Komine ◽  
...  
Keyword(s):  
Body Fat ◽  
High Fat ◽  
Fat Accumulation ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
High Sucrose

scholarly journals Obesity, not a high fat, high sucrose diet alone, induced glucose intolerance and cardiac dysfunction during pregnancy and postpartum

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Eunhee Chung ◽  
Kassandra Gonzalez ◽  
Sarah L. Ullevig ◽  
John Zhang ◽  
Masataka Umeda
Keyword(s):  
Cardiovascular Disease ◽  
Glucose Intolerance ◽  
Systolic Function ◽  
Reproductive Age ◽  
Cardiometabolic Health ◽  
High Fat ◽  
Pregnancy And Postpartum ◽  
Sucrose Diet ◽  
High Sucrose Diet ◽  
High Sucrose

AbstractCardiovascular disease is the leading cause of death in women during pregnancy and the postpartum period. Obesity is an independent risk factor for cardiovascular diseases. Nearly 60% of women of reproductive age are considered overweight or obese, cardiovascular disease morbidity and mortality continue to be pervasive. The objective of this study was to determine the effects of an obesogenic diet on the cardiometabolic health of dams during pregnancy and postpartum. Female mice were fed either a high-fat, high-sucrose diet (HFHS) or a refined control diet (CON) for 8 weeks before initiation of pregnancy and throughout the study period. Mice in the HFHS showed two distinct phenotypes, obesity-prone (HFHS/OP) and obesity resistance (HFHS/OR). Pre-pregnancy obesity (HFHS/OP) induced glucose intolerance before pregnancy and during postpartum. Systolic function indicated by the percent fractional shortening (%FS) was significantly decreased in the HFHS/OP at late pregnancy (vs. HFHS/OR) and weaning (vs. CON), but no differences were found at 6 weeks of postpartum among groups. No induction of pathological cardiac hypertrophy markers was found during postpartum. Plasma adiponectin was decreased while total cholesterol was increased in the HFHS/OP. Our results suggested that obesity, not the diet alone, negatively affected cardiac adaptation during pregnancy and postpartum.

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