scholarly journals Enhancement of the apoptotic effects of Arctii Fructus extracts on cancer cells by the enzymatic bioconversion of lignans

2020 ◽  
Vol 8 (5) ◽  
pp. 2205-2213
Author(s):  
Jung‐Eun Kim ◽  
Nam Hyouck Lee ◽  
Young Ho Kim ◽  
Young Eon Kim ◽  
Tae‐Gyu Lim ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Enzymatic Bioconversion ◽  
Apoptotic Effects

Herbal Mixture Adsorbed to Polyethylene Glycol Microspheres Induces Apoptotic Effects on Breast Cancer Cells

2018 ◽  
Vol 15 (2) ◽  
pp. 227-234 ◽  
Author(s):  
Aliny Aparecida Lopes Ribeiro ◽  
Fabiana Helen da Silva ◽  
Aron Carlos de Melo Cotrim ◽  
Alessandra Lima Deluque ◽  
Patricia Gelli Feres de Marchi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Polyethylene Glycol ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Herbal Mixture ◽  
Apoptotic Effects

scholarly journals Synthesis and pro-apoptotic effects of new sulfonamide derivatives via activating p38/ERK phosphorylation in cancer cells

2014 ◽  
Vol 30 (3) ◽  
pp. 413-419 ◽  
Author(s):  
Ahmet Cumaoglu ◽  
Serkan Dayan ◽  
Asli Ozge Agkaya ◽  
Zehra Ozkul ◽  
Nilgun Kalaycioglu Ozpozan
Keyword(s):  
Cancer Cells ◽  
Erk Phosphorylation ◽  
Apoptotic Effects

Exploring the Colonic Metabolism of Grape and Strawberry Anthocyanins and Their in Vitro Apoptotic Effects in HT-29 Colon Cancer Cells

2016 ◽  
Vol 65 (31) ◽  
pp. 6477-6487 ◽  
Author(s):  
María-Carmen López de las Hazas ◽  
Juana I. Mosele ◽  
Alba Macià ◽  
Iziar A. Ludwig ◽  
María-José Motilva
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Colon Cancer Cells ◽  
Apoptotic Effects ◽  
Ht 29 ◽  
Colonic Metabolism

scholarly journals Apoptotic Effects of Mount Bulgar Viper (Montivipera bulgardaghica) PLA2 and SVMPs Venom Peptide fractions on HeLa and A549 Cancer Cells

Proceedings ◽  
2017 ◽  
Vol 1 (10) ◽  
pp. 1049 ◽  
Author(s):  
Yalcin Erzurumlu ◽  
Daniel Petras ◽  
Bayram Goçmen ◽  
Benjamin-Florian Hempel ◽  
Paul Heiss ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Venom Peptide ◽  
Apoptotic Effects ◽  
Peptide Fractions

scholarly journals Antiproliferative and apoptotic effects of pinocembrin in human prostate cancer cells

2013 ◽  
Vol 8 (3) ◽  
Author(s):  
Zhenyu Chen ◽  
Azhar Rasul ◽  
Chaoyue Zhao ◽  
Faya Martin Millimouno ◽  
Ichiro Tsuji ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Prostate Cancer Cells ◽  
Apoptotic Effects

scholarly journals Correction to: Different apoptotic effects of saxifragifolin C in human breast cancer cells

2018 ◽  
Vol 42 (4) ◽  
pp. 373-374
Author(s):  
Kyung-Ho Kim ◽  
Ji-Yun Kim ◽  
Jong-Hwan Kwak ◽  
Byung Oh Kim ◽  
Suhkneung Pyo
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Apoptotic Effects

scholarly journals Melatonin enhances the apoptotic effects and modulates the changes in gene expression induced by docetaxel in MCF‑7 human breast cancer cells

2017 ◽  
Author(s):  
Carolina Alonso-Gonz�lez ◽  
Javier Men�ndez-Men�ndez ◽  
Alicia Gonz�lez-Gonz�lez ◽  
Alicia Gonz�lez ◽  
Samuel Cos ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Apoptotic Effects ◽  
Mcf 7

Cancer cells with defective RB and CDKN2A are resistant to the apoptotic effects of rapamycin

2021 ◽  
Author(s):  
Sohag Chakraborty ◽  
Matthew B. Utter ◽  
Maria A. Frias ◽  
David A. Foster
Keyword(s):  
Cancer Cells ◽  
Apoptotic Effects

scholarly journals Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells

Biology ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 68
Author(s):  
Khuloud Bajbouj ◽  
Jasmin Shafarin ◽  
Jalal Taneera ◽  
Mawieh Hamad
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Mitochondrial Damage ◽  
Estrogen Signaling ◽  
Ovarian Cancer Cells ◽  
Cellular Iron ◽  
Mitochondrial Membrane Depolarization ◽  
Apoptotic Effects ◽  
Mcf 7

Previous work has shown that although estrogen (E2) disrupts cellular iron metabolism and induces oxidative stress in breast and ovarian cancer cells, it fails to induce apoptosis. However, E2 treatment was reported to enhance the apoptotic effects of doxorubicin in cancer cells. This suggests that E2 can precipitate anti-growth effects that render cancer cells more susceptible to chemotherapy. To investigate such anti-growth non-apoptotic, effects of E2 in cancer cells, MDA-MB-231 and MCF-7 cells were evaluated for the expression of key autophagy and senescence markers and for mitochondrial damage following E2 treatment. Treated cells experienced mitochondrial membrane depolarization along with increased expression of LC3-I/II, Pink1 and LAMP2, increased LC3-II accumulation and increased lysosomal and mitochondrial accumulation and flattening. E2-treated MCF-7 cells also showed reduced P53 and pRb780 expression and increased Rb and P21 expression. Increased expression of the autophagy markers ATG3 and Beclin1 along with increased levels of β-galactosidase activity and IL-6 production were evident in E2-treated MCF-7 cells. These findings suggest that E2 precipitates a form of mitochondrial damage that leads to cell senescence and autophagy in breast cancer cells.

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