Blood flow dynamics and fluid-structure interaction in patient-specific bifurcating cerebral aneurysms

2008 ◽  
Vol 58 (10) ◽  
pp. 1081-1100 ◽  
Author(s):  
Alvaro Valencia ◽  
Darren Ledermann ◽  
Rodrigo Rivera ◽  
Eduardo Bravo ◽  
Marcelo Galvez
Keyword(s):  
Blood Flow ◽  
Fluid Structure Interaction ◽  
Cerebral Aneurysms ◽  
Flow Dynamics ◽  
Patient Specific ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Blood Flow Dynamics

scholarly journals Fluid-Structure Interaction in Abdominal Aortic Aneurysm: Effect of Modeling Techniques

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Shengmao Lin ◽  
Xinwei Han ◽  
Yonghua Bi ◽  
Siyeong Ju ◽  
Linxia Gu
Keyword(s):  
Blood Flow ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Fluid Structure Interaction ◽  
Flow Dynamics ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Abdominal Aortic ◽  
Modeling Techniques ◽  
Blood Flow Dynamics

In this work, the impact of modeling techniques on predicting the mechanical behaviors of abdominal aortic aneurysm (AAA) is systematically investigated. The fluid-structure interaction (FSI) model for simultaneously capturing the transient interaction between blood flow dynamics and wall mechanics was compared with its simplified techniques, that is, computational fluid dynamics (CFD) or computational solid stress (CSS) model. Results demonstrated that CFD exhibited relatively smaller vortexes and tends to overestimate the fluid wall shear stress, compared to FSI. On the contrary, the minimal differences in wall stresses and deformation were observed between FSI and CSS models. Furthermore, it was found that the accuracy of CSS prediction depends on the applied pressure profile for the aneurysm sac. A large pressure drop across AAA usually led to the underestimation of wall stresses and thus the AAA rupture. Moreover, the assumed isotropic AAA wall properties, compared to the anisotropic one, will aggravate the difference between the simplified models with the FSI approach. The present work demonstrated the importance of modeling techniques on predicting the blood flow dynamics and wall mechanics of the AAA, which could guide the selection of appropriate modeling technique for significant clinical implications.

scholarly journals Image-Guided Fluid-Structure Interaction Simulation of Transvalvular Hemodynamics: Quantifying the Effects of Varying Aortic Valve Leaflet Thickness

Fluids ◽  
2019 ◽  
Vol 4 (3) ◽  
pp. 119 ◽  
Author(s):  
Anvar Gilmanov ◽  
Alexander Barker ◽  
Henryk Stolarski ◽  
Fotis Sotiropoulos
Keyword(s):  
Blood Flow ◽  
Aortic Valve ◽  
Heart Valve ◽  
Fluid Structure Interaction ◽  
Maximum Velocity ◽  
Patient Specific ◽  
Hemodynamic Parameters ◽  
Orifice Area ◽  
Fluid Structure ◽  
Structure Interaction

When flow-induced forces are altered at the blood vessel, maladaptive remodeling can occur. One reason such remodeling may occur has to do with the abnormal functioning of the aortic heart valve due to disease, calcification, injury, or an improperly-designed prosthetic valve, which restricts the opening of the valve leaflets and drastically alters the hemodynamics in the ascending aorta. While the specifics underlying the fundamental mechanisms leading to changes in heart valve function may differ from one cause to another, one common and important change is in leaflet stiffness and/or mass. Here, we examine the link between valve stiffness and mass and the hemodynamic environment in aorta by coupling magnetic resonance imaging (MRI) with high-resolution fluid–structure interaction (FSI) computational fluid dynamics to simulate blood flow in a patient-specific model. The thoracic aorta and a native aortic valve were re-constructed in the FSI model from the MRI data and used for the simulations. The effect of valve stiffness and mass is parametrically investigated by varying the thickness (h) of the leaflets (h = 0.6, 2, 4 mm). The FSI simulations were designed to investigate systematically progressively higher levels of valve stiffness by increasing valve thickness and quantifying hemodynamic parameters known to be linked to aortopathy and valve disease. The computed results reveal dramatic differences in all hemodynamic parameters: (1) the geometric orifice area (GOA), (2) the maximum velocity V max of the jet passing through the aortic orifice area, (3) the rate of energy dissipation E ˙ diss ( t ) , (4) the total loss of energy E diss , (5) the kinetic energy of the blood flow E kin ( t ) , and (6) the average magnitude of vorticity Ω a ( t ) , illustrating the change in hemodynamics that occur due to the presence of aortic valve stenosis.

Investigation of two-way fluid-structure interaction of blood flow in a patient-specific left coronary artery

2021 ◽  
pp. 1-18
Author(s):  
Abdulgaphur Athani ◽  
N.N.N. Ghazali ◽  
Irfan Anjum Badruddin ◽  
Sarfaraz Kamangar ◽  
Ali E. Anqi ◽  
...  
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Coronary Artery ◽  
Wall Shear Stress ◽  
Left Coronary Artery ◽  
Fluid Structure Interaction ◽  
Patient Specific ◽  
Hemodynamic Parameters ◽  
Fluid Structure ◽  
Structure Interaction

BACKGROUND: The blood flow in the human artery has been a subject of sincere interest due to its prime importance linked with human health. The hemodynamic study has revealed an essential aspect of blood flow that eventually proved to be paramount to make a correct decision to treat patients suffering from cardiac disease. OBJECTIVE: The current study aims to elucidate the two-way fluid-structure interaction (FSI) analysis of the blood flow and the effect of stenosis on hemodynamic parameters. METHODS: A patient-specific 3D model of the left coronary artery was constructed based on computed tomography (CT) images. The blood is assumed to be incompressible, homogenous, and behaves as Non-Newtonian, while the artery is considered as a nonlinear elastic, anisotropic, and incompressible material. Pulsatile flow conditions were applied at the boundary. Two-way coupled FSI modeling approach was used between fluid and solid domain. The hemodynamic parameters such as the pressure, velocity streamline, and wall shear stress were analyzed in the fluid domain and the solid domain deformation. RESULTS: The simulated results reveal that pressure drop exists in the vicinity of stenosis and a recirculation region after the stenosis. It was noted that stenosis leads to high wall stress. The results also demonstrate an overestimation of wall shear stress and velocity in the rigid wall CFD model compared to the FSI model.

Patient-specific arterial fluid-structure interaction modeling of cerebral aneurysms

2010 ◽  
Vol 65 (1-3) ◽  
pp. 308-323 ◽  
Author(s):  
Kenji Takizawa ◽  
Creighton Moorman ◽  
Samuel Wright ◽  
John Purdue ◽  
Travis McPhail ◽  
...  
Keyword(s):  
Fluid Structure Interaction ◽  
Cerebral Aneurysms ◽  
Patient Specific ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Interaction Modeling

A Comparative Study Based on Patient-Specific Fluid-Structure Interaction Modeling of Cerebral Aneurysms

2011 ◽  
Vol 79 (1) ◽  
Author(s):  
Kenji Takizawa ◽  
Tyler Brummer ◽  
Tayfun E. Tezduyar ◽  
Peng R. Chen
Keyword(s):  
Comparative Study ◽  
Arterial Wall ◽  
Fluid Structure Interaction ◽  
Cerebral Aneurysms ◽  
Flow Simulation ◽  
Wall Stress ◽  
Patient Specific ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Interaction Modeling

We present an extensive comparative study based on patient-specific fluid-structure interaction (FSI) modeling of cerebral aneurysms. We consider a total of ten cases, at three different locations, half of which ruptured. We use the stabilized space-time FSI technique developed by the Team for Advanced Flow Simulation and Modeling (T⋆AFSM), together with a number of special techniques targeting arterial FSI modeling, which were also developed by the T⋆AFSM. What we look at in our comparisons includes the wall shear stress, oscillatory shear index and the arterial-wall stress and stretch. We also investigate how simpler approaches to computer modeling of cerebral aneurysms perform compared to FSI modeling.

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