Institutional Predoctoral Research Training Grant (NIGMS)

2020 ◽  
Vol 44 (14) ◽  
pp. 8-8
2017 ◽  
Vol 96 (8) ◽  
pp. 957-957

Birkeland AC, Owen JH, Prince ME. 2015. Targeting head and neck cancer stem cells: current advances and future challenges. J Dent Res. 94(11):1516–1523. (Original DOI: 10.1177/0022034515601960) In this article, the funding source was not declared. The Acknowledgments have been updated in the online article as follows: Andrew Birkeland is a Research Fellow funded on a T32 Advanced Research Training in Otolaryngology Program Training Grant (T32 DC005356) funded by the National Institutes of Health NIDCD (National Institute On Deafness And Other Communication Disorders).


Parasitology ◽  
1964 ◽  
Vol 54 (2) ◽  
pp. 327-335 ◽  
Author(s):  
G. C. Kearn

The muscular saucer-shaped haptor of the monogenean parasite Entobdella soleae is attached to the skin of its host Solea solea by means of a suction pressure generated within the sea-water-filled cavity enclosed between the cup-shaped haptor and the skin of the fish. The suction pressure is produced by the action of a pair of extrinsic muscles which are situated in the body of the parasite. Each extrinsic muscle communicates with the haptor by means of a long tendon which passes through a fair-lead in a prop-like accessory sclerite and is inserted on the end of a girder-like anterior hamulus embedded in the roof of the concavity of the haptor. The pull exerted by the muscles lifts the girders and the roof of the suction cup in which they are embedded relative to the props, thereby producing a suction pressure.An electron microscope was used to investigate the ultrastructure of the tendon, which was found to consist largely of unbranched banded fibrils which differed from the collagen fibrils of vertebrate tendon in their diameter and periodicity.I would like to express my thanks to Dr J. Llewellyn for suggesting the problem and for much helpful discussion. I am also grateful to Dr M. P. Osborne for tuition on the cutting of sections for electron microscopy. The work was conducted during the tenure of a Fishery Research Training Grant from the Development Commission.


Parasitology ◽  
1963 ◽  
Vol 53 (1-2) ◽  
pp. 253-263 ◽  
Author(s):  
G. C. Kearn

The life cycle of Entobdella soleae, a monogenean skin-parasite of a marine bottom-living flatfish (Solea solea) has been described and related to the habits of the host, which buries itself in the sediment for some time each day and when not buried rarely moves more than a few centimetres from the sea bottom.The eggs of the parasite are laid by specimens attached to the lower surface of the host and are anchored to sand grains on the sea bottom by an egg stalk bearing sticky droplets. The anchoring device may prevent the eggs from being carried by water currents vertically or laterally out of the region inhabited by soles.The free-swimming oncomiracidium which hatches from the egg invades the anterior part of the upper surface of the fish, which is the only part exposed when the fish is buried in the sand. After a short period of development on the upper surface the parasite emigrates to the lower surface where sexual maturity is reached.Adult parasites, which are distributed randomly on the lower surface, are orientated with the adhesive organ upstream with respect to water currents produced by the forward locomotion of the host, but the parasites are capable of moving from place to place on the lower surface of the fish. This movement of the parasite may be connected with the nature of the food.I wish to thank the Director and Staff of the Plymouth Laboratory and in particular Mr J. E. Green, for invaluable assistance. I am also very grateful to Dr J. Llewellyn for advice and criticism. The work was conducted during the tenure of a Fishery Research Training Grant from the Development Commission.


Parasitology ◽  
1963 ◽  
Vol 53 (3-4) ◽  
pp. 435-447 ◽  
Author(s):  
G. C. Kearn

The form of the egg, the structure of the oncomiracidium and the subsequent development of Entobdella soleae, a monogenean skin parasite of the common sole, are described. The reproductive organs develop in a constant sequence and the parasite is protandrous. Glands of Goto were observed in post-oncomiracidia of all ages.The early embryo of E. soleae possesses eight pairs of marginal hooklets and two pairs of hamuli. One pair of hooklets, centrally situated on the adhesive organ, undergoes metamorphosis and becomes the pair of accessory sclerites associated with the hamuli in the adult.My thanks are due to Dr J. Llewellyn for continued advice and criticism. The work was conducted during the tenure of a Fishery Research Training Grant from the Development Commission.


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