Precision medicine diagnosis and treatment conditions affecting fertility (NICHD)

2019 ◽  
Vol 43 (20) ◽  
pp. 6-6
2017 ◽  
pp. 15-34
Author(s):  
Harry Glorikian ◽  
Malorye Allison Branca

Author(s):  
Jing Yan ◽  
Zhuan Liu ◽  
Shengfang Du ◽  
Jing Li ◽  
Li Ma ◽  
...  

Radiology ◽  
2018 ◽  
Vol 287 (3) ◽  
pp. 732-747 ◽  
Author(s):  
Katja Pinker ◽  
Joanne Chin ◽  
Amy N. Melsaether ◽  
Elizabeth A. Morris ◽  
Linda Moy

2019 ◽  
Vol 1 (4) ◽  
pp. 7-15 ◽  
Author(s):  
S. N. Scherbo ◽  
D. S. Scherbo ◽  
V. A. Bespalova ◽  
T. I. Turkina ◽  
M. I. Savina ◽  
...  

Thanks to the approaches of precision medicine, great strides have been made in the diagnosis and treatment of diabetes mellitus, taking into account the individual characteristics of each patient or subgroups for monogenic subtypes of diabetes and newborn diabetes. For monogenic diabetes, molecular genetics can identify discrete etiological subtypes, the manifestation of which has profound implications for treatment, and predict the further development of concomitant clinical signs that allow early prophylaxis or supportive therapy. In contrast, second-type diabetes mellitus has a polygenic nature, which makes it difficult to define discrete clinical subtypes. The implementation of the approaches of precision medicine in the diagnosis and treatment of diabetes mellitus will allow a targeted selection of drug therapy. This review shows the successful use of precision medicine in monogenic diabetes and the possibilities of this approach to solving problems in diabetes of the second type.


2019 ◽  
Vol 128 (1-2) ◽  
pp. 1-9 ◽  
Author(s):  
Jerry Vockley ◽  
Steven F. Dobrowolski ◽  
Georgianne L. Arnold ◽  
Ruben Bonilla Guerrero ◽  
Terry G.J. Derks ◽  
...  

Author(s):  
Lara Choksey

AbstractThis essay reads Max Ritvo’s poetry through a chronology of precision biomedicine: imaging, diagnosis, and treatment. Ritvo’s construction of a patient-consumer avatar in his poetry reflects his position at a biomedical frontier, while poetic form becomes a way of retrieving bodies from a logic of substitution and surrogacy. A body lying under the weight of relentless, and relentlessly variable, imaging is catapulted through memory to a place by the sea in “The Curve.” In “Poem to My Litter,” the speaker addresses the laboratory mice injected with his tumors, drawing himself closer to them through their shared imprisonment in bodies on their way out of life, and suspending a bioeconomy embedded in a moral economy of sacrifice and faith. If precision medicine depends on making the analogical and metaphorical into common consensus—images that stand in for bodies, codes that stand in for disease—then Ritvo upends its neat architecture. He sticks instead with the messiness of bodies failing to meet an elusive salvation.


Sign in / Sign up

Export Citation Format

Share Document