In vitro release and permeation kinetics of Melaleuca alternifolia (tea tree) essential oil bioactive compounds from topical formulations

2017 ◽  
Vol 32 (5) ◽  
pp. 354-361 ◽  
Author(s):  
Barbara Sgorbini ◽  
Cecilia Cagliero ◽  
Monica Argenziano ◽  
Roberta Cavalli ◽  
Carlo Bicchi ◽  
...  
Keyword(s):  
Essential Oil ◽  
Bioactive Compounds ◽  
In Vitro Release ◽  
Melaleuca Alternifolia ◽  
Topical Formulations ◽  
Tea Tree ◽  
Kinetics Of ◽  
Vitro Release ◽  
Permeation Kinetics

Formulation and In Vitro Release Kinetics of Mucoadhesive Blend Gels Containing Matrine for Buccal Administration

2017 ◽  
Vol 19 (1) ◽  
pp. 470-480 ◽  
Author(s):  
Xiaojin Chen ◽  
Jun Yan ◽  
Shuying Yu ◽  
Pingping Wang
Keyword(s):  
Release Kinetics ◽  
In Vitro Release ◽  
Kinetics Of ◽  
Vitro Release

In vitro release, rheological, and stability studies of mefenamic acid coprecipitates in topical formulations

2010 ◽  
Vol 16 (5) ◽  
pp. 497-510 ◽  
Author(s):  
Tarek A. Ahmed ◽  
Hany M. Ibrahim ◽  
Fathy Ibrahim ◽  
Ahmed M. Samy ◽  
Ehab Fetoh ◽  
...  
Keyword(s):  
Mefenamic Acid ◽  
In Vitro Release ◽  
Stability Studies ◽  
Topical Formulations ◽  
Vitro Release

scholarly journals In Vitro Release Testing of Acyclovir Topical Formulations Using Immersion Cells

2020 ◽  
Author(s):  
Madhur Kulkarni ◽  
Shrikant Potdar ◽  
Abhijit A. Date ◽  
Aditya Marfatiya
Keyword(s):  
In Vitro Release ◽  
Topical Formulations ◽  
Vitro Release ◽  
Release Testing

Evaluation of the in vitro release and permeation of Cordia verbenacea DC essential oil from topical dosage forms

2019 ◽  
Vol 53 ◽  
pp. 101173 ◽  
Author(s):  
Jéssica Domingos da Silva ◽  
Márcio Vinícius Gomes ◽  
Lucio Mendes Cabral ◽  
Valeria Pereira de Sousa
Keyword(s):  
Essential Oil ◽  
In Vitro Release ◽  
Dosage Forms ◽  
Topical Dosage ◽  
Vitro Release ◽  
Topical Dosage Forms

scholarly journals Phenobarbital loaded microemulsion: development, kinetic release and quality control

2016 ◽  
Vol 52 (2) ◽  
pp. 251-264 ◽  
Author(s):  
Kayo Alves Figueiredo ◽  
Jamilly Kelly Oliveira Neves ◽  
José Alexsandro da Silva ◽  
Rivelilson Mendes de Freitas ◽  
André Luis Menezes Carvalho
Keyword(s):  
Analytical Method ◽  
In Vitro Release ◽  
Physicochemical Characterization ◽  
Primary Stability ◽  
Isopropyl Myristate ◽  
Microemulsion System ◽  
Transdermal Application ◽  
Kinetics Of ◽  
Vitro Release

ABSTRACT This study aimed to obtain and characterize a microemulsion (ME) containing phenobarbital (PB). The PB was incorporated in the proportion of 5% and 10% in a microemulsion system containing Labrasol(r), ethanol, isopropyl myristate and purified water. The physicochemical characterization was performed and the primary stability of the ME was evaluated. An analytical method was developed using spectrophotometry in UV = 242 nm. The kinetics of the in vitro release (Franz model) of the ME and the emulsion (EM) containing PB was evaluated. The incorporation of PB into ME at concentrations of 5 and 10% did not change pH and resistance to centrifugation. There was an increase in particle size, a decrease of conductivity and a change in the refractive index in relation to placebo ME. The ME remained stable in preliminary stability tests. The analytical method proved to be specific, linear, precise, accurate and robust. Regarding the kinetics of the in vitro release, ME obtained an in vitro release profile greater than the EM containing PB. Thus, the obtained ME has a potential for future transdermal application, being able to compose a drug delivery system for the treatment of epilepsy.

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