scholarly journals Essential oils in the treatment of respiratory tract diseases highlighting their role in bacterial infections and their anti-inflammatory action: a review

2015 ◽  
Vol 30 (5) ◽  
pp. 331-341 ◽  
Author(s):  
Györgyi Horváth ◽  
Kamilla Ács
Keyword(s):  
Respiratory Tract ◽  
Essential Oils ◽  
Bacterial Infections ◽  
Respiratory Tract Diseases ◽  
Anti Inflammatory ◽  
Inflammatory Action

Claims for locabiotal (L.P.) aerosol - selpharm

1967 ◽  
Vol 5 (8) ◽  
pp. 30-31
Keyword(s):  
Respiratory Tract ◽  
Inflammatory Activity ◽  
Isopropyl Myristate ◽  
Gram Positive ◽  
Gram Negative ◽  
Inflammatory Conditions ◽  
Fungus Extract ◽  
Anti Inflammatory ◽  
Inflammatory Action

Locabiotal Pressurised Aerosol or L.P. Aerosol (Selpharm) is a French preparation of a fungus extract, fusafungine, dispensed under pressure in a nebuliser. It contains 0.25% fusafungine dissolved in isopropyl myristate - fusafungine is insoluble in water - and a mixture of about ten perfume oils. The makers recommend it for all infections and inflammatory conditions of the respiratory tract. They claim that ‘most Gram-positive and Gram-negative pathogens in the respiratory tract are sensitive’, that Locabiotal has ‘anti-inflammatory activity equivalent to prednisone’ and that it is a ‘powerful antibiotic with built-in anti-inflammatory action.’ The preparation has been heavily advertised, and the basic NHS cost of each prescription is 18/-.

scholarly journals Eosinophils and Bacteria, the Beginning of a Story

2021 ◽  
Vol 22 (15) ◽  
pp. 8004
Author(s):  
Edna Ondari ◽  
Esther Calvino-Sanles ◽  
Nicholas J. First ◽  
Monica C. Gestal
Keyword(s):  
Immune Responses ◽  
Respiratory Tract ◽  
Bacterial Infections ◽  
Viral Infections ◽  
Inflammatory Responses ◽  
Current Knowledge ◽  
Parasitic Infections ◽  
Th2 Responses ◽  
A Cell ◽  
Anti Inflammatory

Eosinophils are granulocytes primarily associated with TH2 responses to parasites or immune hyper-reactive states, such as asthma, allergies, or eosinophilic esophagitis. However, it does not make sense from an evolutionary standpoint to maintain a cell type that is only specific for parasitic infections and that otherwise is somehow harmful to the host. In recent years, there has been a shift in the perception of these cells. Eosinophils have recently been recognized as regulators of immune homeostasis and suppressors of over-reactive pro-inflammatory responses by secreting specific molecules that dampen the immune response. Their role during parasitic infections has been well investigated, and their versatility during immune responses to helminths includes antigen presentation as well as modulation of T cell responses. Although it is known that eosinophils can present antigens during viral infections, there are still many mechanistic aspects of the involvement of eosinophils during viral infections that remain to be elucidated. However, are eosinophils able to respond to bacterial infections? Recent literature indicates that Helicobacter pylori triggers TH2 responses mediated by eosinophils; this promotes anti-inflammatory responses that might be involved in the long-term persistent infection caused by this pathogen. Apparently and on the contrary, in the respiratory tract, eosinophils promote TH17 pro-inflammatory responses during Bordetella bronchiseptica infection, and they are, in fact, critical for early clearance of bacteria from the respiratory tract. However, eosinophils are also intertwined with microbiota, and up to now, it is not clear if microbiota regulates eosinophils or vice versa, or how this connection influences immune responses. In this review, we highlight the current knowledge of eosinophils as regulators of pro and anti-inflammatory responses in the context of both infection and naïve conditions. We propose questions and future directions that might open novel research avenues in the future.

scholarly journals Essential Oil Blends: The Potential of Combined Use for Respiratory Tract Infections

Antibiotics ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1517
Author(s):  
Stephanie Leigh-de Rapper ◽  
Alvaro Viljoen ◽  
Sandy van Vuuren
Keyword(s):  
Antimicrobial Activity ◽  
Essential Oil ◽  
Respiratory Tract ◽  
Essential Oils ◽  
Respiratory Tract Infections ◽  
Inhibitory Concentration ◽  
Cupressus Sempervirens ◽  
Brine Shrimp Lethality Assay ◽  
Anti Inflammatory ◽  
Tract Infections

This study investigated the potential efficacy of 369 commercial essential oil combinations for antimicrobial, anti-toxic and anti-inflammatory activity with the aim of identifying synergy among essential oils commonly used in combination by aromatherapists for respiratory purposes. Essential oil combinations were assessed for their antimicrobial activities using a panel of Gram-positive, Gram-negative, and yeast strains associated with respiratory tract infections. The antimicrobial activity was measured by determining the minimal inhibitory concentration (MIC) of microbial growth. The fractional inhibitory concentration index (ΣFIC) was calculated to determine the antimicrobial interactions between the essential oils in the combination. The toxicity of the essential oil combinations was tested in vitro using the brine shrimp lethality assay, the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay on RAW 264.7 mouse macrophage cells and A549 lung cancer cell lines. In addition, an inflammatory response was evaluated measuring nitric oxide production. The essential oils, when in combination, demonstrated an increased antimicrobial effect, a reduction in toxicity and provided improved anti-inflammatory outcomes. Five distinct combinations [Cupressus sempervirens (cypress) in combination with Melaleuca alternifolia (tea tree), Hyssopus officinalis (hyssop) in combination with Rosmarinus officinalis (rosemary), Origanum marjorana (marjoram) in combination with M. alternifolia, Myrtus communis (myrtle) in combination with M. alternifolia and Origanum vulgare (origanum) in combination with M. alternifolia] were found to be the most promising, demonstrating antimicrobial activity, reduced cytotoxicity and improved anti-inflammatory effects. With the increased prevalence of respiratory tract infections and the growing antimicrobial resistance development associated with antimicrobial treatments, this study provides a promising complementary alternative for the appropriate use of a selection of essential oil combinations for use in the respiratory tract.

Bioguided determination of the anti-inflammatory action of STW 5 and STW 6

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
K Nieber ◽  
S Michael ◽  
K Grötzinger ◽  
JW Rauwald ◽  
SN Okpanyi ◽  
...  
Keyword(s):  
Anti Inflammatory ◽  
Inflammatory Action

Evaluation of anti-pyretic activity of Dracaena sanderiana by Brewer’s yeast method

2020 ◽  
Vol 9 (2) ◽  
pp. 32-34
Author(s):  
Pavani C H
Keyword(s):  
Herbal Remedies ◽  
Standard Drug ◽  
Chemical Substances ◽  
Beneficial Effects ◽  
Potential Value ◽  
Plant Effects ◽  
Therapeutic Properties ◽  
Dracaena Sanderiana ◽  
Anti Inflammatory ◽  
Inflammatory Action

These medicinal plants are used to develop a therapy for the disease. To improve the science, investigate the scientific proof and activities validation, therefore the use of various herbal remedies for their pain-relieving and anti-inflammatory action in these current days. includes influence, anti-inflammatory, anti effect, analgesia, effects and some beneficial effects on the GI system. show the potential value of pain relief, cancer prevention and weight loss. According to these plant effects, consider that this present study was mainly based on to investigate and likely to reduce the fever caused by the outdoor and indoor. potential of is evidenced in leave studies. The medicinal plant produces a variety of chemical substances which shows significant therapeutic properties with the standard drug paracetamol.

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