Characteristic odour components of bergamot (Citrus bergamia Risso) essential oil

2006 ◽  
Vol 21 (4) ◽  
pp. 609-615 ◽  
Author(s):  
Masayoshi Sawamura ◽  
Yuji Onishi ◽  
Junko Ikemoto ◽  
Nguyen Thi Minh Tu ◽  
Nguyen Thi Lan Phi
Acta Tropica ◽  
2021 ◽  
Vol 217 ◽  
pp. 105869
Author(s):  
Vivien Patricia Garbin ◽  
Beatriz Munguía ◽  
Jenny Carolina Saldaña ◽  
Cícero Deschamps ◽  
Roger Raupp Cipriano ◽  
...  

2019 ◽  
Vol 34 (6) ◽  
pp. 426-435 ◽  
Author(s):  
Silvia Marzocchi ◽  
Elena Baldi ◽  
Maria Cristina Crucitti ◽  
Moreno Toselli ◽  
Maria Fiorenza Caboni

2020 ◽  
Vol 21 (7) ◽  
pp. 2597 ◽  
Author(s):  
Laura Rombolà ◽  
Damiana Scuteri ◽  
Chizuko Watanabe ◽  
Shinobu Sakurada ◽  
Kengo Hamamura ◽  
...  

The essential oil obtained by the fresh fruit of Citrus bergamia Risso et Poiteau is used worldwide in aromatherapy to reduce pain, facilitate sleep induction, and/or minimize the effects of stress-induced anxiety. Preclinical pharmacological data demonstrate that bergamot essential oil (BEO) modulates specific neurotransmissions and shows an anxiolytic-relaxant effect not superimposable to that of the benzodiazepine diazepam, suggesting that neurotransmissions, other than GABAergic, could be involved. Several studies on essential oils indicate a role for serotonergic (5-HT) neurotransmission in anxiety. Interestingly, among serotonergic receptors, the 5-HT1A subtype seems to play a key role in the control of anxiety. Here, we report that modulation of the 5-HT1A receptor by selective agonist ((±)8-OH-DPAT) or antagonist (WAY-100635) may influence some of the anxiolytic-relaxant effects of BEO in Open Field and Elevated Plus Maze tests.


Author(s):  
Giuseppina Gioffrè ◽  
Domenica Ursino ◽  
Maria Laura Concetta Labate ◽  
Angelo Maria Giuffrè

Bergamot (Citrus bergamia, Risso) grows exclusively in the province of Reggio Calabria (Southern Italy). Most part of this territory lies on by the Ionian or the Tyrrhenian sea, with over 700 kilometers of coastline, it has one of the highest values of heliophany in Italy and it is protected, from the Northern winds, by the Aspromonte mountain massif. Most part of the bergamot cultivation area is located between Scilla (West) and Monasterace (East) in a coastal strip with a width up to 12 km from the coast. Bergamot fruit is produced between November and March in relation to the geographical area. Over the last decades, environmental climate changes occurred also in this area. This phenomenon, together with new applied industrial processes may have influenced the bergamot essential oil composition. In addition, the modern analytical apparatus gives more detailed information. The aim of this review is to describe the evolution of studies on the volatile fraction of the bergamot peel essential oil over the years.


2018 ◽  
Vol 137 ◽  
pp. 566-576 ◽  
Author(s):  
Daniel Gonçalves ◽  
Cristina Chiyoda Koshima ◽  
Fábio Rodolfo Miguel Batista ◽  
Christianne Elisabete da Costa Rodrigues

Encyclopedia ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 152-176
Author(s):  
Marco Valussi ◽  
Davide Donelli ◽  
Fabio Firenzuoli ◽  
Michele Antonelli

Bergamot essential oil (BEO) is the result of the mechanical manipulation (cold pressing) of the exocarp (flavedo) of the hesperidium of Citruslimon (L.) Osbeck Bergamot Group (synonym Citrus × bergamia Risso & Poit.), resulting in the bursting of the oil cavities embedded in the flavedo and the release of their contents. It is chemically dominated by monoterpene hydrocarbons (i.e., limonene), but with significant percentages of oxygenated monoterpenes (i.e., linalyl acetate) and of non-volatile oxygen heterocyclic compounds (i.e., bergapten).


Toxins ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 275
Author(s):  
Alessandro Maugeri ◽  
Giovanni Enrico Lombardo ◽  
Laura Musumeci ◽  
Caterina Russo ◽  
Sebastiano Gangemi ◽  
...  

The plant kingdom has always been a treasure trove for valuable bioactive compounds, and Citrus fruits stand out among the others. Bergamottin (BRG) and 5-geranyloxy-7-methoxycoumarin (5-G-7-MOC) are two coumarins found in different Citrus species with well-acknowledged pharmacological properties. Previously, they have been claimed to be relevant in the anti-proliferative effects exerted by bergamot essential oil (BEO) in the SH-SY5Y human neuroblastoma cells. This study was designed to verify this assumption and to assess the mechanisms underlying the anti-proliferative effect of both compounds. Our results demonstrate that BRG and 5-G-7-MOC are able to reduce the proliferation of SH-SY5Y cells, inducing apoptosis and increasing cell population in sub-G0/G1 phase. Moreover, we demonstrated the pro-oxidant activity of the two coumarins that increased reactive oxygen species and impaired mitochondrial membrane potential. From a molecular point of view, BRG and 5-G-7-MOC were able to modulate apoptosis related factors at both protein and gene levels. Lastly, we evaluated the synergistic effect of their combination, finding that the highest synergy was observed at a concentration ratio similar to that occurring in the BEO, supporting our initial hypothesis. Taken together, our results deepen the knowledge regarding the effect of BRG and 5-G-7-MOC in SH-SY5Y cells, emphasizing the relevance of their cooperation in achieving this effect.


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