Squirrel consuming “poisonous” mushrooms

Kenji Suetsugu; Koichi Gomi

doi:10.1002/fee.2443

A Review on Phytochemistry and Pharmacology of Medicinal as well as Poisonous Mushrooms

Mini-Reviews in Medicinal Chemistry ◽

10.2174/1389557517666170927144119 ◽

2018 ◽

Vol 18 (13) ◽

pp. 1095-1109 ◽

Cited By ~ 8

Author(s):

Diksha Sharma ◽

V. P. Singh ◽

N. K. Singh

Keyword(s):

Poisonous Mushrooms

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Toxic Syndromes in Acute Poisonings by Conditionally Edible and Poisonous Mushrooms

EMERGENCY MEDICINE ◽

10.22141/2224-0586.2.73.2016.74795 ◽

2016 ◽

Vol 0 (2.73) ◽

pp. 111 ◽

Cited By ~ 1

Author(s):

N.V. Kurdil ◽

V.M. Padalka ◽

O.V. Ivashchenko ◽

O.H. Lutsenko ◽

A.H. Bohomol ◽

...

Keyword(s):

Poisonous Mushrooms

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Edible and Poisonous Mushrooms of the World

Field Mycology ◽

10.1016/s1468-1641(10)60241-1 ◽

2004 ◽

Vol 5 (1) ◽

pp. 35

Keyword(s):

The World ◽

Poisonous Mushrooms

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Molecular identification of poisonous mushrooms using nuclear ITS region and peptide toxins: a retrospective study on fatal cases in Thailand

The Journal of Toxicological Sciences ◽

10.2131/jts.41.65 ◽

2016 ◽

Vol 41 (1) ◽

pp. 65-76 ◽

Cited By ~ 15

Author(s):

Sittiporn Parnmen ◽

Sujitra Sikaphan ◽

Siriwan Leudang ◽

Thitiya Boonpratuang ◽

Achariya Rangsiruji ◽

...

Keyword(s):

Retrospective Study ◽

Molecular Identification ◽

Its Region ◽

Nuclear Its ◽

Peptide Toxins ◽

Poisonous Mushrooms

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Novel Cyclic Peptides from Lethal Amanita Mushrooms through a Genome-Guided Approach

Journal of Fungi ◽

10.3390/jof7030204 ◽

2021 ◽

Vol 7 (3) ◽

pp. 204

Author(s):

Shengwen Zhou ◽

Xincan Li ◽

Yunjiao Lüli ◽

Xuan Li ◽

Zuo H. Chen ◽

...

Keyword(s):

Mass Spectrometry ◽

Cyclic Peptides ◽

Cyclic Peptide ◽

Amino Acid Residues ◽

Fragment Ions ◽

Peptide Pair ◽

A Genome ◽

Peptide Toxins ◽

Poisonous Mushrooms ◽

Large Peptide

Most species in the genus Amanita are ectomycorrhizal fungi comprising both edible and poisonous mushrooms. Some species produce potent cyclic peptide toxins, such as α-amanitin, which places them among the deadliest organisms known to mankind. These toxins and related cyclic peptides are encoded by genes of the “MSDIN” family (named after the first five amino acid residues of the precursor peptides), and it is largely unknown to what extent these genes are expressed in the basidiocarps. In the present study, Amanita rimosa and Amanita exitialis were sequenced through the PacBio and Illumina techniques. Together with our two previously sequenced genomes, Amanita subjunquillea and Amanita pallidorosea, in total, 46 previously unknown MSDIN genes were discovered. The expression of over 80% of the MSDIN genes was demonstrated in A. subjunquillea. Through a combination of genomics and mass spectrometry, 12 MSDIN genes were shown to produce novel cyclic peptides. To further confirm the results, three of the cyclic peptides were chemically synthesized. The tandem mass spectrometry (MS/MS) spectra of the natural and the synthetic peptides shared a majority of the fragment ions, demonstrating an identical structure between each peptide pair. Collectively, the results suggested that the genome-guided approach is reliable for identifying novel cyclic peptides in Amanita species and that there is a large peptide reservoir in these mushrooms.

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Rapid Species Identification of Cooked Poisonous Mushrooms by Using Real-Time PCR

Applied and Environmental Microbiology ◽

10.1128/aem.02082-07 ◽

2008 ◽

Vol 74 (10) ◽

pp. 3306-3309 ◽

Cited By ~ 24

Author(s):

Kazuhiko Maeta ◽

Tomoya Ochi ◽

Keisuke Tokimoto ◽

Norihiro Shimomura ◽

Nitaro Maekawa ◽

...

Keyword(s):

Real Time ◽

Species Identification ◽

Real Time Pcr ◽

Specific Test ◽

Specific Identification ◽

Specific Fluorescence ◽

Species Specific ◽

Poisonous Mushrooms

ABSTRACT Species-specific identification of the major cooked and fresh poisonous mushrooms in Japan was performed using a real-time PCR system. Specific fluorescence signals were detected, and no nonspecific signals were detected. Therefore, we succeeded in developing a species-specific test for the identification of poisonous mushrooms within 1.5 h.

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