Preferential biomagnification of aryl hydrocarbon hydroxylase- inducing polychlorinated biphenyl congeners in the Lake Michigan, USA, lower food web

2002 ◽  
Vol 21 (2) ◽  
pp. 334-341
Author(s):  
Annette G. Trowbridge ◽  
Deborah L. Swackhamer
Keyword(s):  
Food Web ◽  
Lake Michigan ◽  
Polychlorinated Biphenyl ◽  
Aryl Hydrocarbon Hydroxylase ◽  
Aryl Hydrocarbon

Embryotoxicity, teratogenicity, and aryl hydrocarbon hydroxylase activity in forster's terns on green bay, lake michigan

1987 ◽  
Vol 42 (1) ◽  
pp. 176-184 ◽  
Author(s):  
David J. Hoffman ◽  
Barnett A. Rattner ◽  
Louis Sileo ◽  
Douglas Docherty ◽  
Timothy J. Kubiak
Keyword(s):  
Lake Michigan ◽  
Aryl Hydrocarbon Hydroxylase ◽  
Hydroxylase Activity ◽  
Green Bay ◽  
Aryl Hydrocarbon ◽  
Aryl Hydrocarbon Hydroxylase Activity

Induction of Aryl Hydrocarbon Hydroxylase Activity in Cell Cultures by Aroclors, Residues from Yusho Oil Samples, and Polychlorinated Biphenyl Residues from Fish Samples

1982 ◽  
Vol 65 (4) ◽  
pp. 838-841
Author(s):  
William J Trotter ◽  
Susan J V Young ◽  
James L Casterline ◽  
June A Bradlaw ◽  
Laverne R Kamps
Keyword(s):  
Polychlorinated Biphenyl ◽  
Hepatoma Cell ◽  
Hepatoma Cell Line ◽  
Aryl Hydrocarbon Hydroxylase ◽  
Florisil Column ◽  
Aryl Hydrocarbon ◽  
Fish Samples ◽  
Florisil Column Chromatography ◽  
Aroclor 1242 ◽  
Rice Oil

Abstract Four Aroclor reference materials, cleaned-up extracts of 2 Yusho rice oil samples, and cleaned-up extracts of 3 fish samples containing polychlorinated biphenyl (PCB) residues were tested for their ability to induce aryl hydrocarbon hydroxylase (AHH) activity in a rat hepatoma cell line. Before the AHH bioassay, the samples were fractionated by a Florisil column chromatographic method. All samples contained about 1000 fig PCBs before Florisil column chromatography. The first Florisil eluate contains about 95% of the PCBs in a typical Aroclor, and the second contains the more polar or adsorbent PCB congeners. In this study, the first eluate for all samples produced no quantifiable AHH activity. The second Florisil eluates of both Aroclors 1242 and 1248 induced AHH activity, whereas these eluates of both Aroclors 1254 and 1260 did not. This difference may be due to the presence in Aroclors 1242 and 1248 of 3,3',4,4'-tetrachlorobiphenyl, which has not been detected in Aroclors 1254 and 1260. The second Florisil eluates of the fish samples induced somewhat less AHH activity than did Aroclor 1242 or 1248. The second Florisil eluates of the PCB residues from Yusho rice oil samples induced significantly greater AHH activity than these eluates of either Aroclor 1242 or 1248, perhaps because Yusho rice oil contains a greater amount of polychlorinated dibenzofurans than PCB commercial mixtures on a PCB equivalent basis.

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