scholarly journals Chronic Embryo‐Larval Exposure of Fathead Minnows to the Pharmaceutical Drug Metformin: Survival, Growth, and Microbiome Responses

2021 ◽  
Author(s):  
Joanne L. Parrott ◽  
Victoria E. Restivo ◽  
Karen A. Kidd ◽  
Juliet Zhu ◽  
Kallie Shires ◽  
...  
Keyword(s):  
Fathead Minnows ◽  
Pharmaceutical Drug

Development of apical pits in chloride cells of the gills of Pimephales promelas after chronic exposure to acid water

1983 ◽  
Vol 41 ◽  
pp. 462-463
Author(s):  
Richard L. Leino ◽  
Jon G. Anderson ◽  
J. Howard McCormick
Keyword(s):  
Confidence Interval ◽  
Chronic Exposure ◽  
Lake Superior ◽  
Pimephales Promelas ◽  
Chloride Cells ◽  
Fathead Minnows ◽  
Secondary Lamellae ◽  
Untreated Water ◽  
Water Ph ◽  
Flow Through

Groups of 12 fathead minnows were exposed for 129 days to Lake Superior water acidified (pH 5.0, 5.5, 6.0 or 6.5) with reagent grade H2SO4 by means of a multichannel toxicant system for flow-through bioassays. Untreated water (pH 7.5) had the following properties: hardness 45.3 ± 0.3 (95% confidence interval) mg/1 as CaCO3; alkalinity 42.6 ± 0.2 mg/1; Cl- 0.03 meq/1; Na+ 0.05 meq/1; K+ 0.01 meq/1; Ca2+ 0.68 meq/1; Mg2+ 0.26 meq/1; dissolved O2 5.8 ± 0.3 mg/1; free CO2 3.2 ± 0.4 mg/1; T= 24.3 ± 0.1°C. The 1st, 2nd and 3rd gills were subsequently processed for LM (methacrylate), TEM and SEM respectively.Three changes involving chloride cells were correlated with increasing acidity: 1) the appearance of apical pits (figs. 2,5 as compared to figs. 1, 3,4) in chloride cells (about 22% of the chloride cells had pits at pH 5.0); 2) increases in their numbers and 3) increases in the % of these cells in the epithelium of the secondary lamellae.

Polysaccharides and oligosaccharides designing: Development of new families of pharmaceutical drug

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
C Delattre ◽  
P Michaud ◽  
JY Berthon ◽  
L Rios
Keyword(s):  
Pharmaceutical Drug

Dynamics of isopropylphenyl diphenyl phosphate in fathead minnows

Chemosphere ◽  
1983 ◽  
Vol 12 (6) ◽  
pp. 799-807 ◽  
Author(s):  
James N. Huckins ◽  
Jimmie D. Petty
Keyword(s):  
Fathead Minnows ◽  
Diphenyl Phosphate
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