Evaluation of potential mechanisms of atrazine-induced reproductive impairment in fathead minnow (Pimephales promelas) and Japanese medaka (Oryzias latipes)

2016 ◽  
Vol 35 (9) ◽  
pp. 2230-2238 ◽  
Author(s):  
Catherine A. Richter ◽  
Diana M. Papoulias ◽  
Jeffrey J. Whyte ◽  
Donald E. Tillitt
Keyword(s):  
Fathead Minnow ◽  
Pimephales Promelas ◽  
Oryzias Latipes ◽  
Japanese Medaka ◽  
Reproductive Impairment

Toxicity of oil sands acid-extractable organic fractions to freshwater fish: Pimephales promelas (fathead minnow) and Oryzias latipes (Japanese medaka)

Chemosphere ◽  
2017 ◽  
Vol 171 ◽  
pp. 168-176 ◽  
Author(s):  
Anthony E. Bauer ◽  
Richard A. Frank ◽  
John V. Headley ◽  
Kerry M. Peru ◽  
Andrea J. Farwell ◽  
...  
Keyword(s):  
Freshwater Fish ◽  
Oil Sands ◽  
Fathead Minnow ◽  
Pimephales Promelas ◽  
Oryzias Latipes ◽  
Japanese Medaka ◽  
Organic Fractions

scholarly journals Serum vitellogenin levels and reproductive impairment of male Japanese Medaka (Oryzias latipes) exposed to 4-tert-octylphenol.

1999 ◽  
Vol 107 (5) ◽  
pp. 385-390 ◽  
Author(s):  
S Gronen ◽  
N Denslow ◽  
S Manning ◽  
S Barnes ◽  
D Barnes ◽  
...  
Keyword(s):  
Oryzias Latipes ◽  
Japanese Medaka ◽  
Reproductive Impairment

Differential Sensitivity to In Vitro Inhibition of Cytochrome P450 Aromatase (CYP19) Activity Among 18 Freshwater Fishes

2019 ◽  
Vol 170 (2) ◽  
pp. 394-403 ◽  
Author(s):  
Jon A Doering ◽  
Daniel L Villeneuve ◽  
Kellie A Fay ◽  
Eric C Randolph ◽  
Kathleen M Jensen ◽  
...  
Keyword(s):  
Aromatase Inhibitors ◽  
Fathead Minnow ◽  
Pimephales Promelas ◽  
Endocrine Disrupting Chemicals ◽  
Differential Sensitivity ◽  
Japanese Medaka ◽  
Laboratory Model ◽  
Native Fishes ◽  
Ecological Risk Assessments

Abstract There is significant concern regarding potential impairment of fish reproduction associated with endocrine disrupting chemicals. Aromatase (CYP19) is a steroidogenic enzyme involved in the conversion of androgens to estrogens. Inhibition of aromatase by chemicals can result in reduced concentrations of estrogens leading to adverse reproductive effects. These effects have been extensively investigated in a small number of laboratory model fishes, such as fathead minnow (Pimephales promelas), Japanese medaka (Oryzias latipes), and zebrafish (Danio rerio). But, differences in sensitivity among species are largely unknown. Therefore, this study took a first step toward understanding potential differences in sensitivity to aromatase inhibitors among fishes. Specifically, a standard in vitro aromatase inhibition assay using subcellular fractions of whole tissue homogenates was used to evaluate the potential sensitivity of 18 phylogenetically diverse species of freshwater fish to the nonsteroidal aromatase inhibitor fadrozole. Sensitivity to fadrozole ranged by more than 52-fold among these species. Five species were further investigated for sensitivity to up to 4 additional nonsteroidal aromatase inhibitors, letrozole, imazalil, prochloraz, and propiconazole. Potencies of each of these chemicals relative to fadrozole ranged by up to 2 orders of magnitude among the 5 species. Fathead minnow, Japanese medaka, and zebrafish were among the least sensitive to all the investigated chemicals; therefore, ecological risks of aromatase inhibitors derived from these species might not be adequately protective of more sensitive native fishes. This information could guide more objective ecological risk assessments of native fishes to chemicals that inhibit aromatase.

Use of the Japanese Medaka ( Oryzias latipes ) and Guppy ( Poecilia reticulata ) in Carcinogenesis Testing Under National Toxicology Program Protocols

2003 ◽  
Vol 31 (1) ◽  
pp. 88-91 ◽  
Author(s):  
William E. Hawkins ◽  
William W. Walker ◽  
John W. Fournie ◽  
C. Steve Manning ◽  
Rena M. Krol
Keyword(s):  
Poecilia Reticulata ◽  
Oryzias Latipes ◽  
Japanese Medaka ◽  
National Toxicology Program

Responses in a Fathead Minnow (Pimephales promelas) Lifecycle Test and in Wild White Sucker (Catostomus commersoni) Exposed to a Canadian Bleached Kraft Mill Effluent

2010 ◽  
Vol 45 (2) ◽  
pp. 187-200 ◽  
Author(s):  
Joanne L. Parrott ◽  
L. Mark Hewitt ◽  
Tibor G. Kovacs ◽  
Deborah L. MacLatchy ◽  
Pierre H. Martel ◽  
...  
Keyword(s):  
Egg Production ◽  
Fathead Minnow ◽  
Pimephales Promelas ◽  
Fish Reproduction ◽  
White Sucker ◽  
Catostomus Commersoni ◽  
Liver Size ◽  
Paper Mill Effluent ◽  
Kraft Mill Effluent ◽  
Kraft Mill

Abstract To evaluate currently available bioassays for their use in investigating the causes of pulp and paper mill effluent effects on fish reproduction, the responses of wild white sucker (Catostomus commersoni) collected from the receiving environment at the bleached kraft mill at La Tuque, Quebec, were compared with responses of fathead minnow (Pimephales promelas) exposed to effluent in a laboratory lifecycle test. White sucker collected at effluent exposed sites had increased liver size but none of the reproductive effects that had been documented in earlier field studies at this site. Exposure to 1, 3, 10, 30, and 100% bleached kraft mill effluent (BKME) in the lab led to significantly decreased length, but increased weight and liver size in male fathead minnow. Female length was also decreased and liver size was increased at high effluent exposures. Most effluent concentrations (1 to 30%) significantly increased egg production compared with controls. The fathead minnow lifecycle assay mirrored the effects seen in wild fish captured downstream of the BKME discharge. These results will be used to select short-term fish tests for investigating the causes of and solutions to the effects of mill effluents on fish reproduction.

scholarly journals nLethal and sublethal effects of diluted bitumen and conventional oil on fathead minnow (Pimephales promelas) larvae exposed during their early development

2021 ◽  
pp. 105884
Author(s):  
Roxanne Bérubé ◽  
Charles Gauthier ◽  
Thibault Bourdin ◽  
Marilou Bouffard ◽  
Gaëlle Triffault-Bouchet ◽  
...  
Keyword(s):  
Early Development ◽  
Fathead Minnow ◽  
Sublethal Effects ◽  
Pimephales Promelas ◽  
Conventional Oil
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