Particle-specific toxic effects of differently shaped zinc oxide nanoparticles to zebrafish embryos (Danio rerio )

2014 ◽  
Vol 33 (12) ◽  
pp. 2859-2868 ◽  
Author(s):  
Jing Hua ◽  
Martina G. Vijver ◽  
Michael K. Richardson ◽  
Farooq Ahmad ◽  
Willie J.G.M. Peijnenburg
Keyword(s):  
Zinc Oxide ◽  
Danio Rerio ◽  
Zinc Oxide Nanoparticles ◽  
Toxic Effects ◽  
Oxide Nanoparticles ◽  
Zebrafish Embryos

scholarly journals Zinc Oxide Nanoparticles: Therapeutic Benefits and Toxicological Hazards

2018 ◽  
Vol 5 (1) ◽  
pp. 16-22 ◽  
Author(s):  
Said Said Elshama ◽  
Metwally E. Abdallah ◽  
Rehab I. Abdel-Karim
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Lymphatic System ◽  
Toxic Effects ◽  
Oxide Nanoparticles ◽  
Chemotherapeutic Drugs ◽  
Widespread Application ◽  
Hematological Indices ◽  
Therapeutic Benefits ◽  
Neurological System

Despite the widespread application of zinc oxide nanoparticles in biomedicine, their use is still a controversial issue. Zinc oxide nanoparticles were reported to have therapeutic benefits. However, they were reported to have toxicological hazards as well. Several studies reported the antibacterial, anticancer, antioxidant, and immunomodulatory effects of zinc oxide nanoparticles. Additionally, zinc oxide nanoparticles were used in sunscreens. Furthermore, the ability to use zinc oxide nanoparticles as an adjuvant treatment to alleviate the toxic effects of chemotherapeutic drugs has been reported. However, zinc oxide nanoparticles were shown to induce toxic effects in different body organs and systems. The affected organs included liver, spleen, kidney, stomach, pancreas, heart and lung. In addition, zinc oxide nanoparticles were reported to adversely affect the neurological system, lymphatic system, hematological indices, sex hormones levels, and fetal development. The toxic effects of zinc oxide nanoparticles were based on their concentration, their dose, the route of their administration, and the time of exposure to those particles. Thus, it is crucial to assess their efficacy and safety to determine their toxicological risks and therapeutic benefits.

Acute toxic effects of zinc oxide nanoparticles on Hydra magnipapillata

2018 ◽  
Vol 205 ◽  
pp. 130-139 ◽  
Author(s):  
Ade Yamindago ◽  
Nayun Lee ◽  
Seonock Woo ◽  
Hyosun Choi ◽  
Ji Young Mun ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Toxic Effects ◽  
Oxide Nanoparticles ◽  
Hydra Magnipapillata ◽  
Acute Toxic

scholarly journals Toxic effects of zinc oxide nanoparticles combined with vitamin C and casein phosphopeptides on gastric epithelium cells and the intestinal absorption of mice

RSC Advances ◽  
2018 ◽  
Vol 8 (46) ◽  
pp. 26078-26088 ◽  
Author(s):  
Tianjiao Gu ◽  
Chenjie Yao ◽  
Kangkang Zhang ◽  
Chenchen Li ◽  
Lin Ding ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Vitamin C ◽  
Intestinal Absorption ◽  
Zinc Oxide Nanoparticles ◽  
Gastric Epithelium ◽  
Toxic Effects ◽  
Oxide Nanoparticles ◽  
Zno Nps ◽  
Casein Phosphopeptides ◽  
Epithelium Cells

Vitamin C is more powerful than casein phosphopeptides at controlling the combined toxic effects induced by ZnO NPs on gastric epithelium cells and intestinal absorption in mice.

Sign in / Sign up

Export Citation Format

Share Document