A novel framework for interpretation of data from the fish short-term reproduction assay (FSTRA) for the detection of endocrine-disrupting chemicals

2014 ◽  
Vol 33 (11) ◽  
pp. 2529-2540 ◽  
Author(s):  
Gerald T. Ankley ◽  
Kathleen M. Jensen
Keyword(s):  
Endocrine Disrupting Chemicals ◽  
Short Term ◽  
Endocrine Disrupting

Short-term effects of endocrine-disrupting chemicals on the expression of estrogen-responsive genes in male medaka (Oryzias latipes)

2005 ◽  
Vol 72 (3) ◽  
pp. 239-249 ◽  
Author(s):  
Akemi Yamaguchi ◽  
Hiroshi Ishibashi ◽  
Shinya Kohra ◽  
Koji Arizono ◽  
Nobuaki Tominaga
Keyword(s):  
Endocrine Disrupting Chemicals ◽  
Oryzias Latipes ◽  
Short Term ◽  
Endocrine Disrupting ◽  
Short Term Effects

scholarly journals Short-Term Exposure Effects of Endocrine Disrupting Chemicals on the Brain-Pituitary-Gonadal Axis Response of the Fathead Minnow.

2009 ◽  
Vol 81 (Suppl_1) ◽  
pp. 263-263
Author(s):  
Edward F. Orlando ◽  
Jane Thompson ◽  
Marisol Sepulveda ◽  
Gary Ankley ◽  
Daniel Villeneuve ◽  
...  
Keyword(s):  
Fathead Minnow ◽  
Endocrine Disrupting Chemicals ◽  
Short Term ◽  
Short Term Exposure ◽  
Endocrine Disrupting ◽  
The Brain

scholarly journals In vitro estrogenic, cytotoxic, and genotoxic profiles of the xenoestrogens 8-prenylnaringenine, genistein and tartrazine

2021 ◽  
Author(s):  
Atefeh Nasri ◽  
Raimo Pohjanvirta
Keyword(s):  
Estrogenic Activity ◽  
Endocrine Disrupting Chemicals ◽  
Micronucleus Assay ◽  
Environmental Estrogens ◽  
Short Term ◽  
Endocrine Disrupting ◽  
Health Promoting ◽  
Low Cytotoxicity ◽  
Mcf 7

AbstractPhytoestrogens have been widely praised for their health-promoting effects, whereas synthetic environmental estrogens are considered a toxicological risk to human health. The aim of this study was therefore to compare in vitro the estrogenic, cytotoxic, and genotoxic profiles of three common estrogen-like endocrine-disrupting chemicals: the phytoestrogens 8-prenylnaringenine (8-PN) and genistein and the synthetic xenoestrogen tartrazine. As assessed by a yeast bioreporter assay and estrogen-dependent proliferative response in human mammary gland adenocarcinoma cell line (MCF-7), 8-PN showed the highest estrogen-like activity of the three compounds, followed by tartrazine and genistein. After 24-h incubation on MCF-7 cells, all three compounds exhibited low cytotoxicity in the lactate dehydrogenase assay and no genotoxicity in the micronucleus assay. These results demonstrate that 8-PN, genistein and tartrazine possess variable estrogenic activity but display little cellular toxicity in short-term tests in vitro. No difference between phytoestrogens and a synthetic xenoestrogen could be established.

Effect of Polyphosphate on Removal of Endocrine-Disrupting Chemicals of Nonylphenol and Bisphenol-A by Activated Carbons

2005 ◽  
Vol 40 (4) ◽  
pp. 484-490 ◽  
Author(s):  
Keun J. Choi ◽  
Sang G. Kim ◽  
Chang W. Kim ◽  
Seung H. Kim
Keyword(s):  
Activated Carbon ◽  
Bisphenol A ◽  
Surface Charge ◽  
Activated Carbons ◽  
Endocrine Disrupting Chemicals ◽  
Dipole Interaction ◽  
High Affinity ◽  
Calcium Polyphosphate ◽  
Endocrine Disrupting ◽  
Positively Charged

Abstract This study examined the effect of polyphosphate on removal of endocrine-disrupting chemicals (EDCs) such as nonylphenol and bisphenol-A by activated carbons. It was found that polyphosphate aided in the removal of nonylphenol and bisphenol- A. Polyphosphate reacted with nonylphenol, likely through dipole-dipole interaction, which then improved the nonylphenol removal. Calcium interfered with this reaction by causing competition. It was found that polyphosphate could accumulate on carbon while treating a river. The accumulated polyphosphate then aided nonylphenol removal. The extent of accumulation was dependent on the type of carbon. The accumulation occurred more extensively with the wood-based used carbon than with the coal-based used carbon due to the surface charge of the carbon. The negatively charged wood-based carbon attracted the positively charged calcium-polyphosphate complex more strongly than the uncharged coal-based carbon. The polyphosphate-coated activated carbon was also effective in nonylphenol removal. The effect was different depending on the type of carbon. Polyphosphate readily attached onto the wood-based carbon due to its high affinity for polyphosphate. The attached polyphosphate then improved the nonylphenol removal. However, the coating failed to attach polyphosphate onto the coal-based carbon. The nonylphenol removal performance of the coal-based carbon remained unchanged after the polyphosphate coating.

scholarly journals Endocrine disrupting chemicals mixture and pregnancy glucose levels among women from a fertility clinic

2019 ◽  
Vol 3 ◽  
pp. 27
Author(s):  
Bellavia A ◽  
Mínguez-Alarcón L ◽  
Ford J ◽  
Keller M ◽  
Petrozza J ◽  
...  
Keyword(s):  
Endocrine Disrupting Chemicals ◽  
Glucose Levels ◽  
Endocrine Disrupting ◽  
Fertility Clinic
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