Neuropsychological and clinical findings of Cognitive Remediation Therapy feasibility randomised controlled trial in young people with anorexia nervosa

2021 ◽  
Author(s):  
Lucia Giombini ◽  
Sophie Nesbitt ◽  
Rutendo Kusosa ◽  
Cleo Fabian ◽  
Teo Sharia ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Randomised Controlled Trial ◽  
Young People ◽  
Controlled Trial ◽  
Cognitive Remediation ◽  
Clinical Findings ◽  
Cognitive Remediation Therapy ◽  
Feasibility Randomised Controlled Trial ◽  
Randomised Controlled

scholarly journals Economic evaluation of a randomised controlled trial for anorexia nervosa in adolescents

2007 ◽  
Vol 191 (5) ◽  
pp. 436-440 ◽  
Author(s):  
Sarah Byford ◽  
Barbara Barrett ◽  
Chris Roberts ◽  
Andrew Clark ◽  
Vanessa Edwards ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Cost Effectiveness ◽  
Randomised Controlled Trial ◽  
Young People ◽  
Social Life ◽  
Psychiatric Treatment ◽  
Controlled Trial ◽  
Treatment Strategies ◽  
Patient Treatment ◽  
Randomised Controlled

BackgroundYoung people with anorexia nervosa are often admitted to hospital for treatment. As well as being disruptive to school, family and social life, in-patient treatment is expensive, yet cost-effectiveness evidence is lacking.AimsCost-effectiveness analysis of three treatment strategies for adolescents with anorexia nervosa.MethodUK multicentre randomised, controlled trial comparing in-patient psychiatric treatment, specialist out-patient treatment and general out-patient treatment. Outcomes and costs assessed at baseline, 1 and 2 years.ResultsThere were 167 young people in the trial. There were no statistically significant differences in clinical outcome between the three groups at 2 years. The specialist out-patient group was less costly over the 2-year follow-up (mean total cost £26 738) than the in-patient (£34 531) and general out-patient treatment (£40 794) groups, but this result was not statistically significant. Exploration of the uncertainty associated with the costs and effects of the three treatments suggests that specialist out-patient treatment has the highest probability of being cost-effective.ConclusionsOn the basis of cost-effectiveness, these results support the provision of specialist out-patient services for adolescents with anorexia nervosa.

scholarly journals Protocol investigating the clinical utility of an objective measure of attention, impulsivity and activity (QbTest) for optimising medication management in children and young people with ADHD ‘QbTest Utility for Optimising Treatment in ADHD’ (QUOTA): a feasibility randomised controlled trial

BMJ Open ◽  
2018 ◽  
Vol 8 (2) ◽  
pp. e021104 ◽  
Author(s):  
Charlotte L Hall ◽  
Marilyn James ◽  
Sue Brown ◽  
Jennifer L Martin ◽  
Nikki Brown ◽  
...  
Keyword(s):  
Decision Making ◽  
Randomised Controlled Trial ◽  
Young People ◽  
Controlled Trial ◽  
Medication Management ◽  
Global Functioning ◽  
Feasibility Randomised Controlled Trial ◽  
Management Protocol ◽  
Randomised Controlled

IntroductionAttention-deficit hyperactivity disorder (ADHD) is characterised by symptoms of inattention, hyperactivity and impulsivity. To improve outcomes, the National Institute for Health and Care Excellence ADHD guidelines recommend regular monitoring of symptoms when children commence medication. However, research suggests that routine monitoring rarely happens, and clinicians often rely on subjective information such as reports from parents and teachers to ascertain improvement. These sources can be unreliable and difficult to obtain. The addition of an objective test of attention and activity (QbTest) may improve the objectivity, reliability and speed of clinical decision-making and so reduce the time to identify the optimal medication dose. This study aims to assess the feasibility and acceptability of a QbTest medication management protocol delivered in routine healthcare services for children with ADHD.Method and analysisThis multisite feasibility randomised controlled trial (RCT) will recruit 60 young people (aged 6–17 years old), diagnosed with ADHD, and starting stimulant medication who are seen by Child and Adolescent Mental Health Services or Community Paediatric services. Participants will be randomised into one of two arms. In the experimental arm (QbTest protocol), the participant will complete a QbTest at baseline (prior to medication initiation), and two follow-up QbTests on medication (2–4 weeks and 8–10 weeks later). In the control arm, participants will receive treatment as usual, with at least two follow-up consultations. Measures of parent-, teacher- and clinician-rated symptoms and global functioning will be completed at each time point. Health economic measures will be completed. Clinicians will record treatment decision-making. Acceptability and feasibility of the protocol will be assessed alongside outcome measure completion rates. Qualitative interviews will be conducted.Ethics and disseminationThe findings will be used to inform the development of a fully powered RCT. The results will be submitted for publication in peer-reviewed journals. The study has ethical approval.Trial registration numberNCT03368573; Pre-results.

Youth mentoring for young people at risk of exclusion from secondary school: a feasibility randomised controlled trial

The Lancet ◽  
2016 ◽  
Vol 388 ◽  
pp. S22
Author(s):  
Angela M Beattie ◽  
Heide Busse ◽  
Ruth R Kipping ◽  
David J Gunnell ◽  
Matthew Hickman ◽  
...  
Keyword(s):  
At Risk ◽  
Randomised Controlled Trial ◽  
Young People ◽  
Secondary School ◽  
Controlled Trial ◽  
Youth Mentoring ◽  
Feasibility Randomised Controlled Trial ◽  
Randomised Controlled

scholarly journals Correction to: Optimising medication management in children and young people with ADHD using a computerised test (QbTest): a feasibility randomised controlled trial

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Laura Williams ◽  
Charlotte L. Hall ◽  
Susan Brown ◽  
Boliang Guo ◽  
Marilyn James ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Young People ◽  
Controlled Trial ◽  
Medication Management ◽  
Children And Young People ◽  
Feasibility Randomised Controlled Trial ◽  
Randomised Controlled

An amendment to this paper has been published and can be accessed via the original article.

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