Intolerance of uncertainty and maladaptive perfectionism as maintenance factors for eating disorders and obsessive‐compulsive disorder symptoms

2020 ◽  
Author(s):  
Brenna M. Williams ◽  
Cheri A. Levinson
Keyword(s):  
Eating Disorders ◽  
Obsessive Compulsive Disorder ◽  
Intolerance Of Uncertainty ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Maintenance Factors ◽  
Maladaptive Perfectionism

scholarly journals Predicting Eating Disorder and Anxiety Symptoms Using Anorexia Nervosa and Obsessive-Compulsive Disorder Polygenic Scores

2020 ◽  
Author(s):  
Zeynep Yilmaz ◽  
Katherine Schaumberg ◽  
Matt Halvorsen ◽  
Erica L. Goodman ◽  
Leigh C. Brosof ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Sex Differences ◽  
Anorexia Nervosa ◽  
Eating Disorder ◽  
Obsessive Compulsive Disorder ◽  
Genetic Risk ◽  
Anxiety Symptoms ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Polygenic Scores

Clinical, epidemiological, and genetic findings support an overlap between eating disorders, obsessive-compulsive disorder (OCD), and anxiety symptoms. However, little research has examined the role of genetic factors in the expression of eating disorders and OCD/anxiety phenotypes. We examined whether the anorexia nervosa (AN), OCD, or AN/OCD transdiagnostic polygenic scores (PGS) predict eating disorders, OCD, and anxiety symptoms in a large population-based developmental cohort. Using summary statistics files from the Psychiatric Genomics Consortium Freeze 2 AN and Freeze 1 OCD GWAS, we first conducted an AN/OCD transdiagnostic GWAS meta-analysis and then calculated PGS for AN, OCD, and AN/OCD in participants from the Avon Longitudinal Study of Parents and Children with available genetic and phenotype data on eating disorder, OCD, and anxiety diagnoses and symptoms (sample size 3,212-5,369 per phenotype). We observed sex differences in the PGS prediction of eating disorder, OCD, and anxiety-related phenotypes, with AN genetic risk manifesting at an earlier age and playing a more prominent role in eating disorder phenotypes in boys than in girls. Compulsive exercise was the only phenotype predicted by all three PGS (e.g., PAN(boys)=0.0141 at age 14; POCD(girls)=0.0070 at age 16; PAN/OCD(all)=0.0297 at age 14). Our results suggest that earlier detection of eating disorder, OCD, and anxiety-related symptoms could be made possible by including measurement of genetic risk for these psychiatric conditions while being mindful of sex differences.

Comorbidity of obsessive compulsive disorder in patients with eating disorders

1998 ◽  
Vol 3 (1) ◽  
pp. 37-41 ◽  
Author(s):  
Claudia Lennkh ◽  
A. Strnad ◽  
U. Bailer ◽  
D. Biener ◽  
G. Fodor ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Behavioral and cognitive impulsivity in obsessive–compulsive disorder and eating disorders

2012 ◽  
Vol 200 (2-3) ◽  
pp. 1062-1066 ◽  
Author(s):  
Christina Lynn Boisseau ◽  
Heather Thompson-Brenner ◽  
Catherine Caldwell-Harris ◽  
Elizabeth Pratt ◽  
Todd Farchione ◽  
...  
Keyword(s):  
Eating Disorders ◽  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Cognitive Impulsivity

Behaviour

2015 ◽  
Author(s):  
Allison G. Harvey ◽  
Edward Watkins ◽  
Warren Mansell ◽  
Roz Shafran
Keyword(s):  
Eating Disorders ◽  
Anxiety Disorders ◽  
Sleep Disorders ◽  
Obsessive Compulsive Disorder ◽  
Somatoform Disorders ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Substance Related Disorders ◽  
Safety Signals

Chapter 6 reviews the literature on behavioural processes and draws conclusions about the extent to which they are transdiagnostic. Three behavioural processes considered are escape/avoidance, within-situation safety-seeking behaviours, and ineffective safety-signals. These processes are considered in the context of anxiety disorders and obsessive-compulsive disorder (OCD), somatoform disorders, eating disorders, sleep disorders, and substance-related disorders).

Just to be certain: Confirming the factor structure of the Intolerance of Uncertainty Scale in patients with obsessive-compulsive disorder

2013 ◽  
Vol 27 (5) ◽  
pp. 535-542 ◽  
Author(s):  
Ryan J. Jacoby ◽  
Laura E. Fabricant ◽  
Rachel C. Leonard ◽  
Bradley C. Riemann ◽  
Jonathan S. Abramowitz
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Factor Structure ◽  
Intolerance Of Uncertainty ◽  
Obsessive Compulsive ◽  
Compulsive Disorder
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