scholarly journals Classification of the epilepsies: New concepts for discussion and debate—Special report of the ILAE Classification Task Force of the Commission for Classification and Terminology

2016 ◽  
Vol 1 (1-2) ◽  
pp. 37-44 ◽  
Author(s):  
Ingrid E. Scheffer ◽  
Jacqueline French ◽  
Edouard Hirsch ◽  
Satish Jain ◽  
Gary W. Mathern ◽  
...  
Keyword(s):  
Task Force ◽  
Classification Task ◽  
Special Report ◽  
New Concepts ◽  
Ilae Classification

scholarly journals The ILAE classification of seizures and the epilepsies: Modification for seizures in the neonate. Position paper by the ILAE Task Force on Neonatal Seizures

Epilepsia ◽  
2021 ◽  
Author(s):  
Ronit M. Pressler ◽  
Maria Roberta Cilio ◽  
Eli M. Mizrahi ◽  
Solomon L. Moshé ◽  
Magda L. Nunes ◽  
...  
Keyword(s):  
Task Force ◽  
Position Paper ◽  
Neonatal Seizures ◽  
Ilae Classification

Perfektives und Imperfektives Partizip

2020 ◽  
Vol 28 ◽  
pp. 27-79
Author(s):  
Marc Brose
Keyword(s):  
Tense And Aspect ◽  
History Of Research ◽  
New Concepts ◽  
History Of ◽  
Basic Semantic

“Perfective and Imperfective Participle”: This article deals with the basic semantic opposition of the two types of Egyptian participles, jri̯ and jrr. After an extended overview of the history of research presenting the classical approaches of K. Sethe and A. H. Gardiner, who both used established terms of models of tense and aspect, and also the advanced approaches of W. Schenkel, J. P. Allen, K. Jansen-Winkeln and E. Oreál, who introduced new concepts and terminolgy and so tried to overcome the classical approaches, it is nevertheless shown that the classification of the opposition as “perfective–imperfective”, with modernized definitions in contrast to Gardiner’s, suffices to explain the entire functional range of the two types and that the advanced approaches are not necessary.

In Vitro Toxicology Methods in Risk Assessment

1996 ◽  
Vol 24 (3) ◽  
pp. 325-331
Author(s):  
Iain F. H. Purchase
Keyword(s):  
Risk Assessment ◽  
Hazard Assessment ◽  
Human Health Risk ◽  
In Vitro Test ◽  
In Vitro Methods ◽  
New Concepts ◽  
Vitro Test

The title of this paper is challenging, because the question of how in vitro methods and results contribute to human health risk assessment is rarely considered. The process of risk assessment usually begins with hazard assessment, which provides a description of the inherent toxicological properties of the chemical. The next step is to assess the relevance of this to humans, i.e. the human hazard assessment. Finally, information on exposure is examined, and risk can then be assessed. In vitro methods have a limited, but important, role to play in risk assessment. The results can be used for classification and labelling; these are methods of controlling exposure, analogous to risk assessment, but without considering exposure. The Ames Salmonella test is the only in vitro method which is incorporated into regulations and used widely. Data from this test can, at best, lead to classification of a chemical with regard to genotoxicity, but cannot be used for classification and labelling on their own. Several in vitro test systems which assess the topical irritancy and corrosivity of chemicals have been reasonably well validated, and the results from these tests can be used for classification. The future development of in vitro methods is likely to be slow, as it depends on the development of new concepts and ideas. The in vivo methods which currently have reasonably developed in vitro alternatives will be the easiest to replace. The remaining in vivo methods, which provide toxicological information from repeated chronic dosing, with varied endpoints and by mechanisms which are not understood, will be more difficult to replace.

Ethical Issues Arising in Revising Classifications of Mental Disorders

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
N. Sartorius
Keyword(s):  
Mental Disorders ◽  
Ethical Issues ◽  
Task Force ◽  
Psychiatric Patients ◽  
World Health ◽  
Sufficient Evidence ◽  
Advisory Group ◽  
Diagnostic Systems ◽  
The World

The classification of mental disorders in the International Classification of Diseases (ICD) will be revised in the course of the next three years and its publication (as the 11th Revision of the ICD) will be published, after the approval of the World Health Assembly in 2014. In parallel, the American Psychiatric Association created a Task Force which has begun work on the proposals for the revision of its Diagnostic and Statistical Manual which is to be published as the DSM 5th Revision, in 2012. The World Health Organization has established a special advisory group that should assist it in developing proposals for the classification of mental disorders for the 11th Revision of the ICD and this group collaborates closely with the APA Task Force creating the DSM5 proposals.Numerous ethical issues arise in this process and need to be discussed now so as to inform the process of agreeing on the proposals for the new classifications. They include the importance of an internationally accepted classification as a protection against abuses of psychiatric patients; the need to set the threshold for the diagnosis of a mental disorder at a level ensuring that people with such disorders receive help, the need to avoid imposition of diagnostic systems or categories without sufficient evidence and others. The presentation will briefly discuss the process of constructing the proposals for the new classifications and ways in which the groups established by the WHO and the APA handle these ethical questions.

SYMPOSIUM: BEHAVIOR MODIFICATION BY DRUGS

PEDIATRICS ◽  
1972 ◽  
Vol 49 (5) ◽  
pp. 702-708 ◽  
Author(s):  
C. Keith Conners
Keyword(s):  
Task Force ◽  
Neurological Diseases ◽  
Brain Dysfunction ◽  
Magnesium Pemoline ◽  
Experimental Conditions ◽  
Drug Study ◽  
Stimulant Medications ◽  
Hyperkinetic Child ◽  
Historical Accident

A number of myths have grown up regarding the behavioral effects and use of stimulant medications with children. The first is that there is a type of child uniquely responsive to stimulant compounds, namely, the hyperkinetic child. The second is that the hyperkinetic child is any child who is sufficiently overactive to be considered a menace by adults. The third is that the stimulant medications act primarily to reduce motor activity in a paradoxical "sedative" fashion; and finally, that the drugs do not influence cognitive and perceptual functioning in these children. I believe that these myths are due partly to the historical accident of the manner in which they were first studied, partly to the imprecision in diagnosis and terminology of classification of patients, and partly to the paucity of systematic data on sufficiently large samples under sufficiently varied experimental conditions. I would like to present the results of studies which bear on these issues, and try to draw some general conclusions regarding the present state of knowledge with regard to the use of the various psychostimulants. In this paper I will deal with dextroamphetamine, methylphenidate, and magnesium pemoline. I. METHYLPHENIDATE AND DEXTROAMPHETAMINE The children for this study were referred from schools, pediatricians, and social agencies for either academic or behavioral difficulties, or both. The subjects retained for the drug study comprised about ⅔ of the original referral sample. They were selected to fit the description of the child with "minimal brain dysfunction" as defined by the National Institute of Neurological Diseases and Stroke (NINDS) Task Force I report.

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