scholarly journals Man with ear injury

Author(s):  
Thomas Liu ◽  
Dulaya Santikul ◽  
Matthew Meigh
Keyword(s):  
2020 ◽  
pp. bmjmilitary-2020-001655
Author(s):  
J W Denny ◽  
R J Brown ◽  
M G Head ◽  
J Batchelor ◽  
A S Dickinson

IntroductionThere is little systematic tracking or detailed analysis of investments in research and development for blast injury to support decision-making around research future funding.MethodsThis study examined global investments into blast injury-related research from public and philanthropic funders across 2000–2019. Research databases were searched using keywords, and open data were extracted from funder websites. Data collected included study title, abstract, award amount, funder and year. Individual awards were categorised to compare amounts invested into different blast injuries, the scientific approaches taken and analysis of research investment into blast traumatic brain injury (TBI).ResultsA total of 806 awards were identified into blast injury-related research globally, equating to US$902.1 million (m, £565.9m GBP). There was a general increase in year-on-year investment between 2003 and 2009 followed by a consistent decline in annual funding since 2010. Pre-clinical research received $671.3 m (74.4%) of investment. Brain-related injury research received $427.7 m (47.4%), orthopaedic injury $138.6 m (15.4%), eye injury $63.7 m (7.0%) and ear injury $60.5m (6.7%). Blast TBI research received a total investment of $384.3 m, representing 42.6% of all blast injury-related research. The U.S. Department of Defense funded $719.3 m (80%).ConclusionsInvestment data suggest that blast TBI research has received greater funding than other blast injury health areas. The funding pattern observed can be seen as reactive, driven by the response to the War on Terror, the rising profile of blast TBI and congressionally mandated research.


2005 ◽  
Vol 33 (2) ◽  
pp. 413-417 ◽  
Author(s):  
A.D. Metcalfe ◽  
M.W.J. Ferguson

Biomedical science has made major advances in understanding how cells grow into functioning tissue and the signalling mechanisms used to achieve this are slowly being dissected. Tissue engineering is the application of that knowledge to the building or repairing of organs, including skin, the largest organ in the body. Generally, engineered tissue is a combination of living cells and a supporting matrix. Besides serving as burn coverings, engineered skin substitutes can help patients with diabetic foot ulcers. Today, most of these ulcers are treated with an approach that includes antibiotics, glucose control, special shoes and frequent cleaning and bandaging. The results of such treatments are often disappointing and ineffectual, and scarring remains a major problem, mechanically, cosmetically and psychologically. Within our group we are attempting to address this by investigating novel approaches to skin tissue engineering. We are identifying novel therapeutic manipulations to improve the degree of integration between a tissue engineered dermal construct and the host by both molecular manipulation of growth factors but also by understanding and harnessing mechanisms of regenerative biology. For the purpose of this summary, we will concentrate primarily on the latter of these two approaches in that we have identified a novel mouse mutant that completely and perfectly regenerates skin and cartilaginous components following ear injury. This experimental animal will allow us to characterize not only novel genes involved in the regeneration process but also to utilize cells from such animals in artificial skin equivalents to assess their behaviour compared with normal cells. This approach should allow us to create a tissue-engineered substitute, which more closely resembles the normal regional microanatomy and physiology of the skin, allowing better integration to the host with minimal or no scarring.


2010 ◽  
Vol 143 (2_suppl) ◽  
pp. P262-P263
Author(s):  
Masataka Murakami
Keyword(s):  

1998 ◽  
Vol 23 (1) ◽  
pp. 100-101
Author(s):  
A. M. Shelton ◽  
W. T. Wilsey

Abstract Two separate trials were conducted. Corn for the first trial was planted on 28 May and for the second trial on 12 Jun, both at the Vegetable Crops Research Farm near Geneva, NY. The plants were arranged in a RCB design with four replicates of nine treatments and one check. Plots consisted of seven 25-ft rows of sweet corn on 30-inch centers with 9-inch plant spacing. Blocks were separated by 25 ft. Treatments involved three applications of each insecticide for controlling naturally intesting Lepidoptera. Foliar sprays were applied with a 5-row CO2-pressurized high-boy tractor-mounted boom, having 3 nozzles per row (one over the top and one drop nozzle on each side) with flat fan 110015 tips, and delivering 30 gpa at 47 psi and 2.5 mph. Silwet L-77 spray adjuvant was applied at 0.1% v/v with all treatments. In the first trial, insecticides were applied on 8, 15, and 23 Aug. Treatments for the second trial were applied on 15, 23 Aug, and 2 Sep. Trials were evalu-ated on 2 and 8 Sep for the respective plots by selecting 25 ears from the five treated rows of each plot and evaluating them for ear injury.


1981 ◽  
Vol 25 (3) ◽  
pp. 169
Author(s):  
A. MAN ◽  
S. SEGAL ◽  
S. EZRA ◽  
Gordon D. Larcom

1979 ◽  
Vol 93 (12) ◽  
pp. 1235-1236 ◽  
Author(s):  
R. L. Blair ◽  
D. Hussarau

AbstractTetanus resulting from ear injury is extremely rare. However, the otologist should be aware that it does occur. A case of otogenic tetanus recently treated by the authors is presented.In Western countries tetanus in now a rare disease because of extensive immunization programmes. Otogenic tetanus is extremely uncommon in North America, but occurs more frequently in tropical regions (De and De, 1970).Less than forty new cases of tetanus are seen in the Province of Ontario (population, 8·4 million) each year (Department of Statistics, Government of Ontario).It has been stated that the operative treatment of otogenic tetanus should include radical mastoidectomy (Black and Atkins, 1972). This is probably true in severe cases but milder cases do not require this form of therapy.Most children in Canada receive primary immunization with Diphtheria, Tetanus and Pertussis vaccine (DTP) in the early years of life. However, especially in large urban centres, there is a large non-immunized or partially immunized immigrant population.Tetanus occurring in such an immigrant is described.


2014 ◽  
Vol 43 (3) ◽  
pp. 828-839 ◽  
Author(s):  
Michael J. Brewer ◽  
Gary N. Odvody ◽  
Darwin J. Anderson ◽  
Jeffrey C. Remmers

2017 ◽  
Vol 186 ◽  
pp. 124-130 ◽  
Author(s):  
Zeenath S. Ameen ◽  
Thiphalak Chounthirath ◽  
Gary A. Smith ◽  
Kris R. Jatana

2021 ◽  
Vol 71 (Suppl-1) ◽  
pp. S130-35
Author(s):  
Kamran Ashfaq Ahmed Butt ◽  
Naeem Riaz Bhalli ◽  
Wasif Siddique ◽  
Attique Ahmed ◽  
Maryam Khan ◽  
...  

Objective: To describe the resultant Otologic morbidity and report on the early outcomes following blasts occurring in twin cities of Quetta and Peshawar. Study Design: Case series. Place and Duration of Study: ENT department Tertiary Care Centre Quetta and Tertiary Care Hospital Peshawar. Study period was, from Jan 2013 to Dec 2013. Methodology: All bomb blast patients brought to the hospitals were included in study. Participants completed Symptom Assessment Forms followed by detailed ENT examination and Pure Tone Audiograms on arrival and after 6 weeks. Results: A total of 504 patients were included initially of which 80% of the patients were male. About 57.8% of the patients complained of ear injury, 21.6% of the total patients had tympanic membrane perforation on initial presentation. Chances of spontaneous closure of perforation were 20.9% in our study. Chances of hearing improvement were 17.9% in our study at the end of the study period. Conclusion: Blast related otologic injuries constituted a major source of morbidity The most common type of hearing loss following a blast trauma was mild to moderate conductive type. Chances of recovery of hearing following blast do exist (17.9%). Suspected patients should be regularly assessed and followed up. Much work needs to be done to study the impact of blast trauma on hearing in our country.


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