scholarly journals A clinical decision framework to guide the outpatient treatment of emergency department patients diagnosed with acute pulmonary embolism or deep vein thrombosis: Results from a multidisciplinary consensus panel

2021 ◽  
Vol 2 (6) ◽  
Author(s):  
Christopher Kabrhel ◽  
David R. Vinson ◽  
Alice Marina Mitchell ◽  
Rachel P. Rosovsky ◽  
Anna Marie Chang ◽  
...  
Keyword(s):  
Emergency Department ◽  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
Outpatient Treatment ◽  
Acute Pulmonary Embolism ◽  
Clinical Decision ◽  
Consensus Panel ◽  
Vein Thrombosis ◽  
Emergency Department Patients ◽  
Deep Vein

Clinical Assessment of Fondaparinux for Treatment of Acute Pulmonary Embolism and Acute Deep Vein Thrombosis in Japanese Patients

CHEST Journal ◽  
2010 ◽  
Vol 138 (4) ◽  
pp. 409A ◽  
Author(s):  
Mashio Nakamura ◽  
Yoshiaki Okano ◽  
Hiroki Minamigichi ◽  
Hiroshi Tsujimoto ◽  
Hiromu Nakajima ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
Clinical Assessment ◽  
Acute Pulmonary Embolism ◽  
Japanese Patients ◽  
Vein Thrombosis ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein

Experience in 207 Combined MRI Examinations for Acute Pulmonary Embolism and Deep Vein Thrombosis

2006 ◽  
Vol 186 (6) ◽  
pp. 1686-1696 ◽  
Author(s):  
Alexander Kluge ◽  
Clemens Mueller ◽  
Johannes Strunk ◽  
Uwe Lange ◽  
Georg Bachmann
Keyword(s):  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
Acute Pulmonary Embolism ◽  
Vein Thrombosis ◽  
Deep Vein

scholarly journals Acute pulmonary embolism complicating deep vein thrombosis in a young patient with stroke

2021 ◽  
Vol 11 (2) ◽  
pp. 142-144
Author(s):  
Mohammed Mirazur Rahman ◽  
Farjana Binte Habib ◽  
Ahmed Imran Kabir ◽  
Samprity Islam ◽  
Rajashish Chakrabortty ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
Lower Limb ◽  
Acute Pulmonary Embolism ◽  
Successful Outcome ◽  
Shortness Of Breath ◽  
Vein Thrombosis ◽  
Doppler Study ◽  
Left Lower Limb ◽  
Deep Vein

Acute pulmonary embolism is one of the most common causes of vascular death after myocardial infarction and cerebrovascular accidents. It usually presents with severe chest pain and shortness of breath and occasionally occurs in the background of deep vein thrombosis. A 32-year-old male presented with swelling of left lower limb and shortness of breath. Subsequent investigations revealed that he developed DVT of left lower limb and pulmonary embolism. However, in general, if left untreated, pulmonary embolism is associated with an overall mortality of up to 30 percent compared with 2 to 11 percent in those treated with anticoagulation. Early diagnosis by D-dimer, computed tomograpgy pulmonary angiogram and doppler study of the left lower limb and prompt intervention through low molecular weight heparin and rivaroxaban led to a successful outcome in our case. Birdem Med J 2021; 11(2): 142-144

scholarly journals Bleeding and recurrent VTE with apixaban vs warfarin as outpatient treatment: time-course and subgroup analyses

2020 ◽  
Vol 4 (2) ◽  
pp. 432-439 ◽  
Author(s):  
Derek Weycker ◽  
Gail DeVecchis Wygant ◽  
Jennifer D. Guo ◽  
Theodore Lee ◽  
Xuemei Luo ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
Outpatient Treatment ◽  
Time Points ◽  
Vein Thrombosis ◽  
Study Population ◽  
Recurrent Vte ◽  
Deep Vein ◽  
Bridge Therapy

Abstract In the phase 3 trial Apixaban for the Initial Management of Pulmonary Embolism and Deep-Vein Thrombosis as First-Line Therapy, apixaban was noninferior to enoxaparin, overlapped and followed by warfarin, in the treatment of venous thromboembolism (VTE) with significantly less bleeding; in a real-world evaluation, risks for bleeding and recurrent VTE were lower with apixaban vs warfarin plus parenteral anticoagulant (PAC) bridge therapy. The present study extends this research by comparing outcomes over time and within selected subgroups. A retrospective observational cohort design and 4 US private health care claims databases were used. Study population included patients who initiated outpatient treatment with apixaban or warfarin (plus PAC bridge therapy) for VTE. Major bleeding, clinically relevant nonmajor (CRNM) bleeding, and recurrent VTE were compared during the 180-day follow-up period, at selected follow-up time points (days 21, 90, 180), and within subgroups (pulmonary embolism [PE] with or without deep vein thrombosis [DVT], DVT only, provoked VTE, unprovoked VTE) using multivariable shared frailty models. Study population consisted of 20 561 apixaban patients and 35 080 warfarin patients; baseline characteristics were comparable. Overall, at selected follow-up time points, and within the aforementioned subgroups, adjusted risks were lower among apixaban vs warfarin patients: major bleeding, by 27% to 39%, CRNM bleeding, by 17% to 28%, and recurrent VTE, by 25% to 39% (all P ≤ .01). In this real-world study of VTE patients, risks of bleeding and recurrent VTE were lower among apixaban (vs warfarin) patients during the 180-day follow-up period, at selected follow-up time points, and within subgroups defined by index VTE episode.

scholarly journals Current challenges in diagnostic imaging of venous thromboembolism

Blood ◽  
2015 ◽  
Vol 126 (21) ◽  
pp. 2376-2382 ◽  
Author(s):  
Menno V. Huisman ◽  
Frederikus A. Klok
Keyword(s):  
Pulmonary Embolism ◽  
Deep Vein Thrombosis ◽  
Venous Thromboembolism ◽  
Clinical Decision ◽  
Pretest Probability ◽  
Current Standard ◽  
Diagnostic Algorithms ◽  
Vein Thrombosis ◽  
Compression Ultrasound ◽  
Deep Vein

Abstract Because the clinical diagnosis of deep-vein thrombosis and pulmonary embolism is nonspecific, integrated diagnostic approaches for patients with suspected venous thromboembolism have been developed over the years, involving both non-invasive bedside tools (clinical decision rules and D-dimer blood tests) for patients with low pretest probability and diagnostic techniques (compression ultrasound for deep-vein thrombosis and computed tomography pulmonary angiography for pulmonary embolism) for those with a high pretest probability. This combination has led to standardized diagnostic algorithms with proven safety for excluding venous thrombotic disease. At the same time, it has become apparent that, as a result of the natural history of venous thrombosis, there are special patient populations in which the current standard diagnostic algorithms are not sufficient. In this review, we present 3 evidence-based patient cases to underline recent developments in the imaging diagnosis of venous thromboembolism.

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