scholarly journals Whole blood transfusion versus component therapy in trauma resuscitation: a systematic review and meta‐analysis

2020 ◽  
Vol 1 (4) ◽  
pp. 633-641 ◽  
Author(s):  
Ellen Crowe ◽  
Stacia M. DeSantis ◽  
Austin Bonnette ◽  
Jan O. Jansen ◽  
Jose‐Miguel Yamal ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Transfusion ◽  
Whole Blood ◽  
Meta Analysis ◽  
Trauma Resuscitation

Hemostatic techniques to reduce blood transfusion after primary TKA: a meta-analysis and systematic review

2019 ◽  
Vol 139 (12) ◽  
pp. 1785-1796 ◽  
Author(s):  
Zhenyue Dong ◽  
Li Han ◽  
Yifan Song ◽  
Jianchao Qi ◽  
Fei Wang
Keyword(s):  
Systematic Review ◽  
Blood Transfusion ◽  
Meta Analysis

scholarly journals Transfusion-Transmitted Malaria: A Systematic Review and Meta-analysis

2019 ◽  
Vol 6 (7) ◽  
Author(s):  
Ehsan Ahmadpour ◽  
Masoud Foroutan-Rad ◽  
Hamidreza Majidiani ◽  
Sirous Mehrani Moghaddam ◽  
Kareem Hatam-Nahavandi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Transfusion ◽  
Blood Donors ◽  
Meta Analysis ◽  
Plasmodium Species ◽  
Diagnostic Methods ◽  
Sub Saharan Africa ◽  
Screening Methods ◽  
Original Research ◽  
Malaria Parasitemia

Abstract Background Malaria transmission through blood transfusion is an accidental but preventable cause of malaria infection and is increasingly becoming a matter of concern for blood transfusion services. This systematic review was conducted to provide a summary of evidence about the prevalence of Plasmodium infection in asymptomatic blood donors and the effectiveness of screening methods used based on the available literature. Methods PRISMA guidelines were followed. Scopus, PubMed, Science Direct, and EMBASE were searched from 1982 to October 10, 2017. All peer-reviewed original research articles describing the prevalence of malaria parasitemia in blood donors with different diagnostic methods were included. The random-effects model was applied to assess the effects of heterogeneity among the selected studies. Incoherence and heterogeneity between studies were quantified by I2 index and Cochran’s Q test. Publication and population bias was assessed with funnel plots and Egger’s regression asymmetry test. All statistical analyses were performed using Stata (version 2.7.2). Results Seventy-one studies from 21 countries, 5 continents, were included in the present systematic review. The median prevalence of malaria parasitemia among 984 975 asymptomatic healthy blood donors was 10.54%, 5.36%, and 0.38% by microscopy, molecular methods (polymerase chain reaction), and rapid diagnostic tests, respectively. The most commonly detected Plasmodium species was P. falciparum. Conclusions This systematic review demonstrates that compared with other transfusion-linked infections, that is, HIV, HCV, and HBV, transfusion-transmitted malaria is one of the most significant transfusion-associated infections especially in Sub-Saharan Africa. Future work must aim to understand the clinical significance of transfusion-transmitted malaria in malaria-endemic settings.

Risk of HIV-1 transmission for parenteral exposure and blood transfusion: a systematic review and meta-analysis

AIDS ◽  
2006 ◽  
Vol 20 (6) ◽  
pp. 805-812 ◽  
Author(s):  
Rebecca F Baggaley ◽  
Marie-Claude Boily ◽  
Richard G White ◽  
Michel Alary
Keyword(s):  
Systematic Review ◽  
Blood Transfusion ◽  
Meta Analysis ◽  
Parenteral Exposure ◽  
Hiv 1

scholarly journals A Systematic Review and Meta-Analysis of the Clinical Appropriateness of Blood Transfusion in China

Medicine ◽  
2015 ◽  
Vol 94 (50) ◽  
pp. e2164 ◽  
Author(s):  
Changtai Zhu ◽  
Yulu Gao ◽  
Zhiqiang Li ◽  
Qinyun Li ◽  
Zongshuai Gao ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Transfusion ◽  
Meta Analysis

scholarly journals 1484 Tranexamic Acid Use to Decrease Blood Loss in Primary Shoulder and Elbow Replacement: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
J Varma ◽  
R Donovan ◽  
M Whitehouse ◽  
S Kunutsor ◽  
A Blom
Keyword(s):  
Systematic Review ◽  
Blood Transfusion ◽  
Length Of Stay ◽  
Blood Loss ◽  
Tranexamic Acid ◽  
Meta Analysis ◽  
Postoperative Blood Loss ◽  
Perioperative Blood Loss ◽  
Transfusion Requirements ◽  
Elbow Replacement

Abstract Tranexamic acid (TXA) is an inexpensive, commonly used antifibrinolytic agent that has been shown to significantly reduce perioperative blood loss and transfusion requirements after total hip and knee replacement. We conducted a systematic review and meta-analysis to synthesise the latest evidence regarding the effects of TXA on blood loss in total shoulder replacement (TSR) and total elbow replacement (TER). We systematically searched MEDLINE, EMBASE and CENTRAL from inception to 03 September 2020 for randomised controlled trial (RCTs) and observational studies. Our primary outcome was blood loss, and secondary outcomes included the need for blood transfusion and venous thromboembolic (VTE) complications. Four RCTs and five retrospective cohort studies (RCS) met eligibility criteria for TSRs, but none for TERs. RCT data determined that TXA administration significantly decreased estimated total blood loss, postoperative blood loss, change in haemoglobin (Hb) and total Hb loss when compared to placebo. RCS data demonstrated significant association between TXA administration and decreased in postoperative blood loss, change in Hb, change in Hct and length of stay. This meta-analysis demonstrates that TXA administration in primary TSR significantly decreases blood loss compared with placebo and is associated with lower blood loss and shorter length of stay compared with no treatment with no increase in VTE complications. TXA administration should be part of a wider blood management strategy to minimise perioperative blood loss and blood transfusion requirements in patients undergoing TSR. Further research is needed to demonstrate if a similar treatment benefit exists in patients undergoing TER.

scholarly journals Whole blood versus component therapy for haemostatic resuscitation of major bleeding: a protocol for a systematic review and meta-analysis

BMJ Open ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. e043967
Author(s):  
Anna E Ssentongo ◽  
Paddy Ssentongo ◽  
Emily Heilbrunn ◽  
Lacee Laufenberg Puopolo ◽  
Vernon M Chinchilli ◽  
...  
Keyword(s):  
Systematic Review ◽  
Major Bleeding ◽  
Whole Blood ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Primary Data ◽  
Blood Component ◽  
Geographical Differences ◽  
Blood Component Therapy ◽  
Haemostatic Resuscitation

IntroductionThere is a renewed interest in the use of whole blood (WB) to manage patients with life-threatening bleeding. We aimed to estimate mortality and complications risk between WB and blood component therapy for haemostatic resuscitation of major bleeding.MethodsWe will conduct a systematic review and meta-analysis of studies published between 1 January 1980 and 1 January 2020, identified from PubMed and Scopus databases. Population will be patients who require blood transfusion (traumatic operative, obstetric and gastrointestinal bleeding). Intervention is WB transfusion such as fresh WB (WB unit stored for less than 48 hours), leukoreduced modified WB (with platelets removed during filtration), warm fresh WB (stored warm at 22°C for up to 8 hours and then for a maximum of an additional 24 hours at 4°C). The primary outcomes will be the 24-hour and 30-day survival rates (in-hospital mortality). Comparator is blood component therapy (red blood cells, fresh-frozen plasma and platelets given together in a 1:1:1 unit ratio). The Cochrane risk of bias tool for randomised controlled trials and Risk Of Bias In Non-randomised Studies - of Interventions (ROBINS-I) for observation studies will be used to assess the risk of bias of included studies. We will use random-effects models for the pooling of studies. Interstudy heterogeneity will be assessed by the Cochran Q statistic, where p<0.10 will be considered statistically significant and quantified by I2 statistic, where I2 ≥50% will indicate substantial heterogeneity. We will perform subgroup and meta-regression analyses to assess geographical differences and other study-level factors explaining variations in the reported mortality risk. Results will be reported as risk ratios and their 95% CIs.Ethics and disseminationNo ethics clearance is required as no primary data will be collected. The results will be presented at scientific conferences and published in a peer-reviewed journal.

Risk factors for blood transfusion in Cesarean section: A systematic review and meta-analysis

2021 ◽  
Author(s):  
Kinza Iqbal ◽  
Ayman Iqbal ◽  
Sawai Singh Rathore ◽  
Jawad Ahmed ◽  
Shajeea Arshad Ali ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Blood Transfusion ◽  
Cesarean Section ◽  
Meta Analysis
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