scholarly journals Maternally inherited genetic variants of CADPS 2 are present in Autism Spectrum Disorders and Intellectual Disability patients

2014 ◽  
Vol 6 (6) ◽  
pp. 795-809 ◽  
Author(s):  
Elena Bonora ◽  
Claudio Graziano ◽  
Fiorella Minopoli ◽  
Elena Bacchelli ◽  
Pamela Magini ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Intellectual Disability ◽  
Genetic Variants ◽  
Autism Spectrum ◽  
Spectrum Disorders

scholarly journals Maternally inherited genetic variants of CADPS 2 are present in Autism Spectrum Disorders and Intellectual Disability patients

2014 ◽  
Vol 6 (12) ◽  
pp. 1639-1639 ◽  
Author(s):  
Elena Bonora ◽  
Claudio Graziano ◽  
Fiorella Minopoli ◽  
Elena Bacchelli ◽  
Pamela Magini ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Intellectual Disability ◽  
Genetic Variants ◽  
Autism Spectrum ◽  
Spectrum Disorders

scholarly journals Intellectual Disability and Autism Spectrum Disorders

2018 ◽  
Vol 7 (1) ◽  
pp. 38-44 ◽  
Author(s):  
A.B. Sorokin
Keyword(s):  
Autism Spectrum Disorders ◽  
Intellectual Disability ◽  
Diagnostic Category ◽  
Autism Spectrum ◽  
Diagnostic Measures ◽  
The Usa ◽  
Spectrum Disorders

The article introduces the modern understanding of intellectual disability as a diagnostic category. It is based on the description of the structure, recommended for professional use in the USA. The necessity of intellect testing in individuals with autism spectrum disorders is discussed alongside with its place among other diagnostic measures

Divided attention capacity in adults with autism spectrum disorders and without intellectual disability

Autism ◽  
2009 ◽  
Vol 13 (3) ◽  
pp. 229-243 ◽  
Author(s):  
Hans Bogte ◽  
Bert Flamma ◽  
Jaap Van Der Meere ◽  
Herman Van Engeland
Keyword(s):  
Autism Spectrum Disorders ◽  
Intellectual Disability ◽  
Divided Attention ◽  
Autism Spectrum ◽  
Adults With Autism ◽  
Spectrum Disorders

scholarly journals Association of maternal diabetes with neurodevelopmental disorders: autism spectrum disorders, attention-deficit/hyperactivity disorder and intellectual disability

2020 ◽  
Author(s):  
Shuyun Chen ◽  
Sixian Zhao ◽  
Christina Dalman ◽  
Håkan Karlsson ◽  
Renee Gardner
Keyword(s):  
Diabetes Mellitus ◽  
Attention Deficit Hyperactivity Disorder ◽  
Autism Spectrum Disorders ◽  
Intellectual Disability ◽  
Attention Deficit ◽  
Neurodevelopmental Disorders ◽  
Maternal Diabetes ◽  
Autism Spectrum ◽  
Hyperactivity Disorder ◽  
Spectrum Disorders

Abstract Background Maternal diabetes has been associated with a risk of neurodevelopmental disorders (NDDs) in offspring, though the common co-occurrence of autism spectrum disorders (ASD), attention-deficit/hyperactivity disorder (ADHD) and intellectual disability (ID) is rarely considered, nor is the potential for confounding by shared familial factors (e.g. genetics). Methods This population-based cohort study used data from Psychiatry Sweden, a linkage of Swedish national registers, to follow 2 369 680 individuals born from 1987 to 2010. We used population-averaged logit models to examine the association between exposure to maternal type 1 diabetes mellitus (T1DM), pre-gestational type 2 diabetes mellitus (T2DM) or gestational diabetes mellitus (GDM), and odds of NDDs in offspring. Subgroup analysis was then performed to investigate the timings of GDM diagnosis during pregnancy and its effect on the odds of NDDs in offspring. We compared these results to models considering paternal lifetime T1DM and T2DM as exposures. Results Overall, 45 678 individuals (1.93%) were diagnosed with ASD, 20 823 (0.88%) with ID and 102 018 (4.31%) with ADHD. All types of maternal diabetes were associated with odds of NDDs, with T2DM most strongly associated with any diagnosis of ASD (odds ratioadjusted 1.37, 95% confidence interval 1.03–1.84), ID (2.09, 1.53–2.87) and ADHD (1.43, 1.16–1.77). Considering common co-morbid groups, the associations were strongest between maternal diabetes and diagnostic combinations that included ID. Paternal T1DM and T2DM diagnoses were also associated with offspring NDDs, but these associations were weaker than those with maternal diabetes. Diagnosis of GDM between 27 and 30 weeks of gestation was generally associated with the greatest risk of NDDs in offspring, with the strongest associations for outcomes that included ID. Conclusion The association of maternal diabetes with NDDs in offspring varies depending on the co-morbid presentation of the NDDs, with the greatest odds associated with outcomes that included ID. Results of paternal-comparison studies suggest that the above associations are likely to be partly confounded by shared familial factors, such as genetic liability.

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