3D-printed individual labware in biosciences by rapid prototyping: A proof of principle

2014 ◽  
Vol 15 (1) ◽  
pp. 51-56 ◽  
Author(s):  
Tim H. Lücking ◽  
Franziska Sambale ◽  
Sascha Beutel ◽  
Thomas Scheper
Keyword(s):  
Rapid Prototyping ◽  
3D Printed ◽  
Proof Of Principle

scholarly journals Novel 3D-Printed MEMS Magnetometer with Optical Detection

Proceedings ◽  
2018 ◽  
Vol 2 (13) ◽  
pp. 783 ◽  
Author(s):  
Matthias Kahr ◽  
Wilfried Hortschitz ◽  
Harald Steiner ◽  
Michael Stifter ◽  
Andreas Kainz ◽  
...  
Keyword(s):  
3D Printing ◽  
Product Development ◽  
Rapid Prototyping ◽  
Low Cost ◽  
High Accuracy ◽  
Structural Performance ◽  
Sensitivity Measurement ◽  
Optical Readout ◽  
3D Printed ◽  
Working Principle

This paper reports a novel 3D printed MEMS magnetometer with optical readout, which demonstrates the advantages of 3D printing technology in terms of rapid prototyping. Low-cost and fast product development cycles favour 3D printing as an effective tool. Sensitivity measurement with such devices indicate high accuracy and good structural performance, considering material and technological uncertainties. This paper is focusing on the novelty of the rapid, 3D-printing prototyping approach and verification of the working principle for printed MEMS magnetometers.

scholarly journals The Use of Composite Materials in 3D Printing

2020 ◽  
Vol 4 (2) ◽  
pp. 42 ◽  
Author(s):  
Ignazio Blanco
Keyword(s):  
Composite Materials ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Polymer Matrix ◽  
Chemical Properties ◽  
Modified Polymer ◽  
Research Activities ◽  
Physico Chemical ◽  
3D Printed ◽  
Limited Spectrum

Nowadays, all production, from the smallest ones to large companies, and research activities are affected by the use of 3D printing technology. The major limitation, in order to cover as many fields of application as possible, is represented by the set of 3D printable materials and their limited spectrum of physico-chemical properties. To expand this spectrum and employ the 3D-printed objects in areas such as biomedical, mechanical, electronical and so on, the introduction of fibers or particles in a polymer matrix has been widely studied and applied. In this review, all those studies that proposed modified polymer presenting advantages associated with rapid prototyping are reported.

scholarly journals Negligible-cost microfluidic device fabrication using 3D-printed interconnecting channel scaffolds

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0245206
Author(s):  
Harry Felton ◽  
Robert Hughes ◽  
Andrea Diaz-Gaxiola
Keyword(s):  
Rapid Prototyping ◽  
Point Of Care ◽  
Low Cost ◽  
Microfluidic Channel ◽  
Microfluidic Devices ◽  
Device Fabrication ◽  
Appropriate Technology ◽  
Channel Cross Section ◽  
Microfluidic Systems ◽  
3D Printed

This paper reports a novel, negligible-cost and open-source process for the rapid prototyping of complex microfluidic devices in polydimethylsiloxane (PDMS) using 3D-printed interconnecting microchannel scaffolds. These single-extrusion scaffolds are designed with interconnecting ends and used to quickly configure complex microfluidic systems before being embedded in PDMS to produce an imprint of the microfluidic configuration. The scaffolds are printed using common Material Extrusion (MEX) 3D printers and the limits, cost & reliability of the process are evaluated. The limits of standard MEX 3D-printing with off-the-shelf printer modifications is shown to achieve a minimum channel cross-section of 100×100 μm. The paper also lays out a protocol for the rapid fabrication of low-cost microfluidic channel moulds from the thermoplastic 3D-printed scaffolds, allowing the manufacture of customisable microfluidic systems without specialist equipment. The morphology of the resulting PDMS microchannels fabricated with the method are characterised and, when applied directly to glass, without plasma surface treatment, are shown to efficiently operate within the typical working pressures of commercial microfluidic devices. The technique is further validated through the demonstration of 2 common microfluidic devices; a fluid-mixer demonstrating the effective interconnecting scaffold design, and a microsphere droplet generator. The minimal cost of manufacture means that a 5000-piece physical library of mix-and-match channel scaffolds (100 μm scale) can be printed for ~$0.50 and made available to researchers and educators who lack access to appropriate technology. This simple yet innovative approach dramatically lowers the threshold for research and education into microfluidics and will make possible the rapid prototyping of point-of-care lab-on-a-chip diagnostic technology that is truly affordable the world over.

scholarly journals A 3D-printed hand-powered centrifuge for molecular biology

2019 ◽  
Author(s):  
Gaurav Byagathvalli ◽  
Aaron F. Pomerantz ◽  
Soham Sinha ◽  
Janet Standeven ◽  
M. Saad Bhamla
Keyword(s):  
Molecular Biology ◽  
Low Cost ◽  
Power Source ◽  
Medical Diagnostics ◽  
Resource Limited Settings ◽  
Resource Limited ◽  
External Power Source ◽  
External Power ◽  
3D Printed ◽  
Proof Of Principle

The centrifuge is an essential tool for many aspects of research and medical diagnostics. However, conventional centrifuges are often inaccessible outside of conventional laboratory settings, such as remote field sites, require a constant external power source, and can be prohibitively costly in resource-limited settings and STEM-focused programs. Here we present the 3D-Fuge, a 3D-printed hand-powered centrifuge, as a novel alternative to standard benchtop centrifuges. Based on the design principles of a paper-based centrifuge, this 3D-printed instrument increases the volume capacity to 2 mL and can reach hand-powered centrifugation speeds up to 6,000 rpm. The 3D-Fuge devices presented here are capable of centrifugation of a wide variety of different solutions such as spinning down samples for biomarker applications and performing nucleotide extractions as part of a portable molecular lab setup. We introduce the design and proof-of-principle trials that demonstrate the utility of low-cost 3D printed centrifuges for use in remote and educational settings.

A neurosurgical simulation of skull base tumors using a 3D printed rapid prototyping model containing mesh structures

2016 ◽  
Vol 158 (6) ◽  
pp. 1213-1219 ◽  
Author(s):  
Kosuke Kondo ◽  
Naoyuki Harada ◽  
Hiroyuki Masuda ◽  
Nobuo Sugo ◽  
Sayaka Terazono ◽  
...  
Keyword(s):  
Rapid Prototyping ◽  
Skull Base ◽  
Skull Base Tumors ◽  
3D Printed ◽  
Rapid Prototyping Model ◽  
Mesh Structures

scholarly journals Case study research: Optical digitization, reverse engineering and rapid prototyping as a solution in pedal car development process

2018 ◽  
Vol 210 ◽  
pp. 04047
Author(s):  
Pavel Stoklasek ◽  
Tomas Vecera ◽  
Jiri Moravek
Keyword(s):  
Rapid Prototyping ◽  
Reverse Engineering ◽  
Case Study Research ◽  
3D Models ◽  
Design Elements ◽  
Manufacturing Method ◽  
Rear Light ◽  
Vacuum Forming ◽  
3D Printed

The motivation of this work was to find an appropriate manufacturing method for pedal car accessories. This study describes the application of optical digitization, reverse engineering and rapid prototyping in manufacturing process of accessories for handmade pedal car, which imitates an unique historic Czech car, a Škoda 1000 MB, type 990 Roadster. Two well-known design elements, rear light and front indicator, were digitized by non-contact 3D scanner. The digitized 3D models were used as an inputs for reverse engineering. Their shapes were modified due to technological limits of vacuum forming, scaled and used to design of the 3D printed vacuum forming moulds. The final parts were made of transparent foil, trimmed around the perimeter and airbrushed from the inside. The described process served to verify the manufacturability of these accessories before commencing works on a mass-produced pedal cars intended for sale to customers.

scholarly journals The computer-aided design and rapid prototyping fabrication of removable partial denture framework for occlusal rehabilitation: clinical report

2020 ◽  
Vol 9 (12) ◽  
pp. e9891210692
Author(s):  
Adriana da Fonte Porto Carreiro ◽  
Ana Larisse Carneiro Pereira ◽  
Camila Oliveira Paz ◽  
Rachel Gomes Cardoso ◽  
Clebya Rosália Pereira Medeiros ◽  
...  
Keyword(s):  
Rapid Prototyping ◽  
Computer Aided Design ◽  
Clinical Investigation ◽  
Clinical Report ◽  
Chromium Alloy ◽  
Cobalt Chromium ◽  
Intraoral Scanning ◽  
Computer Aided ◽  
3D Printed ◽  
Aided Design

The objective of this case report was to describe the clinical sequence for occlusal vertical dimension (OVD) recovering with the manufacture of removable partial dentures (RPD) produced by computer-aided design and rapid prototyping. The patient presented to the Dentistry Department of the Federal University of Rio Grande do Norte reporting dissatisfaction with the superior RPD. At clinical investigation, a fracture in the minor connector and support at the region of tooth 15 was observed, in addition to severe OVD loss. In this case, after obtaining correct OVD, four more sessions were necessary for RPD fabrication. In the first appointment, intraoral scanning was performed to generate STL files used for path of insertion determination in the CAD software. The need for a guide plane on tooth 15 was observed, thus a preparation guide was designed and 3Dprinted to aid axial tooth reduction. At the second visit, after mouth preparation, another intraoral scanning was performed to acquire virtual working models. The RPD framework was designed and 3D printed in a castable resin pattern and invested for cobalt-chromium alloy melting. In the third visit, clinical evaluation of the framework and teeth and artificial gingiva colors selection were performed. The articulated models were then 3D printed, enabling pre-fabricated teeth to be assembled and acrylized. On the fourth appointment, RPD was installed and the patient received routine instructions. In this sense, the use of CAD/CAM technologies presented as a valuable tool to enhance restoration of OVD by the manufacturing of RPD.

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