Postpolymerization modification of a hydroxy monolith precursor. Part III. Activation of poly(hydroxyethyl methacrylate-co-pentaerythritol triacrylate) monolith with epoxy functionalities followed by bonding of glycerol, polyamines, and hydroxypropyl-β-cy

2016 ◽  
Vol 37 (23-24) ◽  
pp. 3178-3185 ◽  
Author(s):  
Shantipriya Khadka ◽  
Ziad El Rassi
Keyword(s):  
Hydroxyethyl Methacrylate ◽  
Pentaerythritol Triacrylate

Patterned Poly(2-hydroxyethyl methacrylate) Brushes on Silicon Surfaces Behave as “Tentacles” To Capture Ferritin from Aqueous Solution

2009 ◽  
Vol 1 (7) ◽  
pp. 1525-1532 ◽  
Author(s):  
Jem-Kun Chen ◽  
Zong-Yan Chen ◽  
Han-Ching Lin ◽  
Po-Da Hong ◽  
Feng-Chih Chang
Keyword(s):  
Aqueous Solution ◽  
Silicon Surfaces ◽  
Hydroxyethyl Methacrylate

scholarly journals Effect of 2-hydroxyethyl methacrylate on Streptococcus spp. biofilms

2011 ◽  
Vol 52 (3) ◽  
pp. 193-200 ◽  
Author(s):  
S. D’Ercole ◽  
M. Di Giulio ◽  
R. Grande ◽  
E. Di Campli ◽  
S. Di Bartolomeo ◽  
...  
Keyword(s):  
Hydroxyethyl Methacrylate

scholarly journals Mucoadhesive Nanoparticles for Drug Delivery to the Anterior Eye

Nanomaterials ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1400
Author(s):  
Nicole Mangiacotte ◽  
Graeme Prosperi-Porta ◽  
Lina Liu ◽  
Megan Dodd ◽  
Heather Sheardown
Keyword(s):  
Morphological Analysis ◽  
Phenylboronic Acid ◽  
Spherical Particles ◽  
Target Tissue ◽  
Hydroxyethyl Methacrylate ◽  
Potential Analysis ◽  
Transmission Electron ◽  
Nanoparticle System ◽  
Zeta Potential Analysis

While the use of topical drops for the delivery of drugs to the anterior of the eye is well accepted, it is far from efficient with as little as 5% of the drug instilled on the eye actually reaching the target tissue. The ability to prolong the residence time on the eye is desirable. Based on the acceptability of 2-hydroxyethyl methacrylate based polymers in contact lens applications, the current work focuses on the development of a poly(2-hydroxyethyl methacrylate (HEMA)) nanoparticle system. The particles were modified to allow for degradation and to permit mucoadhesion. Size and morphological analysis of the final polymer products showed that nano-sized, spherical particles were produced. FTIR spectra demonstrated that the nanoparticles comprised poly(HEMA) and that 3-(acrylamido)phenylboronic acid (3AAPBA), as a mucoadhesive, was successfully incorporated. Degradation of nanoparticles containing N,N′-bis(acryloyl)cystamine (BAC) after incubation with DL-dithiothreitol (DTT) was confirmed by a decrease in turbidity and through transmission electron microscopy (TEM). Nanoparticle mucoadhesion was shown through an in-vitro zeta potential analysis.

Sign in / Sign up

Export Citation Format

Share Document