scholarly journals Parallel data acquisition of in-source fragmented glycopeptides to sequence the glycosylation sites of proteins

2016 ◽  
Vol 37 (11) ◽  
pp. 1420-1430 ◽  
Author(s):  
Jingfu Zhao ◽  
Ehwang Song ◽  
Rui Zhu ◽  
Yehia Mechref
Keyword(s):  
Data Acquisition ◽  
Glycosylation Sites ◽  
Parallel Data

Proving the Preclusion of Data Manipulation Using Parallel Data Acquisition in Chromatography

2018 ◽  
Vol 941 ◽  
pp. 2390-2394
Author(s):  
David Thomas Marehn ◽  
Detlef Wilhelm ◽  
Heike Pospisil ◽  
Roberto Pizzoferrato
Keyword(s):  
Data Acquisition ◽  
Best Practice ◽  
Sampling Rate ◽  
Good Manufacturing Practice ◽  
Special Role ◽  
Analytical Instruments ◽  
Data Collector ◽  
Parallel Data ◽  
Time Variations ◽  
Hplc Detector

Traceability has an enormous value for companies, but especially for those working in the regulated environment. It plays a special role in the field of pharmacy with respect to manufacturing, controlling and distributing batches of drugs. Through the guidance of Good Manufacturing Practice (GMP) traceability should be ensured. An increasing number of pharmaceutical companies are member of one of the global pharmacopoeias (United States Pharmacopeia, European Pharmacopeia and Japanese Pharmacopeia). The specifications of these pharmacopoeias describe the best practice in documentation, control, qualification and risk management. But however, the pharmacopoeias are written very generally and do not distinguish between the vendors of the analytical instruments. Here, we analyze how chromatographic analyses and data acquisition rely on a specific vendor of the device and the chromatography data system (CDS), the controlling software. We present a way to compare the data acquisition of different CDSs communicating with HPLC instruments. A newly developed software called Data Collector allows the acquisition of data from a HPLC detector parallel to the controlling CDS in the same run. Two HPLC systems and two different CDSs using a well defined sample standard have been tested. The direct comparison of the acquired data precludes unexpected data manipulations of both tested CDSs and shows that there are primarily deviations between the CDSs due to time variations only which depend on the sampling rate. All in all the Data Collector can be used for the traceability of data acquisition.

Real-time data acquisition and parallel data processing solution for TJ-II Bolometer arrays diagnostic

2006 ◽  
Vol 81 (15-17) ◽  
pp. 1863-1867
Author(s):  
E. Barrera ◽  
M. Ruiz ◽  
S. López ◽  
D. Machón ◽  
J. Vega ◽  
...  
Keyword(s):  
Data Processing ◽  
Data Acquisition ◽  
Real Time ◽  
Time Data ◽  
Parallel Data ◽  
Real Time Data ◽  
Bolometer Arrays ◽  
Processing Solution

Design of a LXI High-Speed Parallel Data Acquisition System

2012 ◽  
Vol 433-440 ◽  
pp. 7588-7593 ◽  
Author(s):  
Qing Hua Shang ◽  
Shu Feng Guo ◽  
Chun Yu Yu ◽  
Dian Shuang Zheng
Keyword(s):  
Data Acquisition ◽  
Data Storage ◽  
High Speed ◽  
Data Acquisition System ◽  
Acquisition System ◽  
Interface Circuit ◽  
Parallel Data ◽  
High Speed Data Acquisition ◽  
High Speed Data ◽  
Automated Data Acquisition

The research on establishing an automated data acquisition system with high speed and accuracy is a hot topic in measurement and testing area. The desire is extremely high in data acquisition systems with high speed, multi-channels and large capacity, therefore research into this field becomes very important and significant. In this paper, a LXI high speed parallel data acquisition system which is combined LXI bus with high-speed data acquisition ability is proposed. And the signal conditioning circuit, ADC, data storage circuit, FPGA main control circuit and LXI interface circuit are introduced in detail. The remote control of the data acquisition system and the high speed transmission of data are realized by using the LXI bus.

Nanoscale “Curtain Rods”: High-Throughput Tools for Studying DNA-Protein Interactions

2008 ◽  
Vol 1138 ◽  
Author(s):  
Teresa Fazio ◽  
Mari-Liis Visnapuu ◽  
Shalom J. Wind ◽  
Eric Greene
Keyword(s):  
Data Acquisition ◽  
Real Time ◽  
Lipid Bilayer ◽  
High Throughput ◽  
Single Molecule ◽  
Protein Interactions ◽  
Massively Parallel ◽  
Dna Interactions ◽  
Parallel Data ◽  
Protein Dna Interactions

AbstractIn this work, we combine nanoscale engineering with single-molecule biology to probe the biochemical interactions between individual proteins and DNA. This approach, a vast improvement over previous methods, constructs a platform to observe thousands of protein-DNA interactions in real time with unprecedented detail. A key challenge in these experiments involves collecting enough statistically relevant data in order to analyze reactions which are designed to be probed individually. “DNA curtains” are formed by flowing the DNA tethered to a lipid bilayer across nanopatterned barriers, facilitating massively parallel data acquisition.

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