scholarly journals Getting started with open-hardware: Development and control of microfluidic devices

2014 ◽  
Vol 35 (16) ◽  
pp. 2370-2377 ◽  
Author(s):  
Eric Tavares da Costa ◽  
Maria F. Mora ◽  
Peter A. Willis ◽  
Claudimir L. do Lago ◽  
Hong Jiao ◽  
...  
Keyword(s):  
Microfluidic Devices ◽  
Open Hardware ◽  
Hardware Development ◽  
And Control

scholarly journals Measurement and control of pressure driven flows in microfluidic devices using an optofluidic flow sensor

2014 ◽  
Vol 8 (5) ◽  
pp. 054123 ◽  
Author(s):  
Mohammad Sadegh Cheri ◽  
Hamidreza Shahraki ◽  
Jalal Sadeghi ◽  
Mohammadreza Salehi Moghaddam ◽  
Hamid Latifi
Keyword(s):  
Microfluidic Devices ◽  
Flow Sensor ◽  
And Control ◽  
Measurement And Control ◽  
Pressure Driven

Microfluidic Applications in Vascular Bioengineering

2011 ◽  
pp. 1-30
Author(s):  
Anand Srinivasan ◽  
José L. López-Ribot ◽  
Anand K. Ramasubramanian
Keyword(s):  
Research Output ◽  
Microfluidic Devices ◽  
New Age ◽  
Current Status ◽  
Small Scale ◽  
Basic Principles ◽  
Microfluidic Flow ◽  
And Control ◽  
Manipulation And Control

Microfluidics is the manipulation and control of fluids in small scale, and has heralded a new age in science as evidenced by the rapid increase in the amount and quality of academic and industrial research output in this area in the recent times. Microfluidics has shown tremendous promise in both fundamental and applied research in the field of vascular bioengineering. In this review, we outline the basic principles of microfluidic flow and fabrication techniques, and describe the recent advances in the applications of microfluidic devices in diagnostic and prognostic vascular bioengineering. The field is still in its infancy and has a great potential for research and development as it matures to deliver commercially viable products. This review, focusing on the current status of microfluidic applications to diagnose and treat blood-related disorders, should be a valuable and opportune addition to the literature of interest to both academia and industry.

scholarly journals Atoms Want to Be Free Too! Expanding the Critique of Intellectual Property to Physical Goods

2012 ◽  
Vol 10 (1) ◽  
pp. 66-76 ◽  
Author(s):  
Johan Söderberg ◽  
Adel Daoud
Keyword(s):  
Political Economy ◽  
Intellectual Property ◽  
Private Property ◽  
The Political ◽  
Information Goods ◽  
Proprietary Software ◽  
Open Hardware ◽  
Hardware Development ◽  
Trade Press ◽  
The Way

“Atoms are the new bits”. That is the latest buzz arising from the Californian trade press. What do we get when this dictum is sampled with the old rallying cry: “Information wants to be free”? We suggest that the predominant, bounded critique of intellectual property is thereby destabilised. Constitutive of that critique was the exceptionality attributed to information goods (bits) vis-a-vis tangible goods (atoms). It was thus intellectual property could be presented as something altogether different from private property. We recognise that this way of framing the issue has had tactical advantages, but contend that it has stood in the way of a deeper understanding of what intellectual property is. When the critique of proprietary software is expanded by an emerging movement for open hardware development, however, the boundary between intellectual property and property as such crumbles. This enables us to renew our critique of the political economy of information.

Microactuators for Fluidic Applications: Principles, Devices, and Systems

2009 ◽  
Vol 6 (4) ◽  
pp. 250-264
Author(s):  
Nadja Adamovic ◽  
Ioanna Giouroudi ◽  
Jovan Matovic ◽  
Zoran Djinovic ◽  
Ulrich Schmid
Keyword(s):  
Environmental Control ◽  
Research Work ◽  
Microfluidic Devices ◽  
Processing Technologies ◽  
Voltage Frequency ◽  
And Control ◽  
Chemical Process Control ◽  
Manipulation And Control ◽  
Opening Up ◽  
Selection Of

Much effort in microfluidics research has been aimed at designing microscale pumps, valves, switches, dispensers, mixers, filters, separators, and so on, which have a major role in the development of innovative systems like chemical process control, bioanalytical devices, medical drug delivery systems, environmental control, and others. Most of these microfluidic devices have one thing in common: the need for precise manipulation and control of small amounts of fluids. MEMS/NEMS research is continuously opening up new knowledge on modeling approaches, novel materials, and MEMS/NEMS processing technologies that stimulate and accelerate the development of new actuation principles and novel actuator configurations. This review paper presents research work on different actuation techniques that are used for the whole range of microfluidic applications. It covers thermomechanical and electrochemical actuation principles, as well as actuation induced with external electric or magnetic fields. It presents a brief explanation of the operating principle of each type of actuator, actuator configuration, its main characteristics, like power consumption, operational voltage, frequency range, and working fluids, and a discussion of comparisons among different actuation schemes. This study compiles and provides some basic guidelines for selection of the actuation schemes that are currently implemented in microfluidic devices.

scholarly journals Subterahertz sensor in microfluidic devices for on-line determination and control of ethanol concentration

2017 ◽  
Vol 35 (6) ◽  
pp. 06GA02
Author(s):  
Salomao Moraes da Silva Junior ◽  
Johan Stiens ◽  
Stanislav Moshkalev ◽  
Jacobus Willibrordus Swart ◽  
Vladimir Matvejev ◽  
...  
Keyword(s):  
Ethanol Concentration ◽  
Microfluidic Devices ◽  
On Line ◽  
And Control

Transient Modelling of Pneumatic Valves in Centrifugal Microfluidic Devices

2016 ◽  
Author(s):  
Michael R. Moon ◽  
Lin Lin
Keyword(s):  
Surface Tension ◽  
Point Of Care ◽  
Low Cost ◽  
Microfluidic Devices ◽  
Novel Technologies ◽  
Fluid Handling ◽  
Pneumatic Valves ◽  
Microfluidic Valves ◽  
And Control ◽  
Micrometer Scale

Point of care medical instruments benefit from compact fluid handling systems in the microliter range. To handle fluid volumes this small, many novel technologies have been studied. Pneumatic valves offer advantages over other microfluidic valves, including robustness and low cost. These valves are used in centrifugal microfluidic devices, a very active area of research, and take advantage of pneumatic and centrifugal pressure to aliquot and control the flow of fluid. The physics of fluids at the micrometer scale are complex and modelling their behavior using CFD software is challenging. Representing adhesion, surface tension, and other multiphase interactions is critical to accurately model microfluidic behavior. Centrifugal devices must also consider Coriolis, centrifugal, and Euler effects. In this study, a pneumatic valve was designed and simulated using commercial CFD software. The device was also fabricated for verification of the simulation. The simulation demonstrated the multiphase interactions of fluid and air within the rotating device. In a transient analysis of the model, a 6 μl volume of water is held in stable equilibrium by a compressed volume of air at low RPM, while at a higher RPM, the fluid is observed to displace the compressed air as a result of Rayleigh-Taylor instability. Actual devices with comparable geometry were built and tested. The behavior of the valve predicted in the model was in agreement with experimental results produced from the actual devices. The results of the simulation captured the stabilizing effect of both pneumatic pressure and surface tension at low RPM, as well as the instability that results from increased centrifugal and Euler pressure at higher RPM.

Effects of Process Parameters on Direct Deposition Hydrogel Molding for the Fabrication Microfluidic Devices

2016 ◽  
Author(s):  
Karen Chang Yan ◽  
John Sperduto ◽  
Christopher Civitello ◽  
Alison McCarthy ◽  
Aren Moy
Keyword(s):  
Process Parameters ◽  
Electrospun Fiber ◽  
Base Material ◽  
Microfluidic Devices ◽  
Direct Writing ◽  
Channel Diameter ◽  
Curing Conditions ◽  
Direct Deposition ◽  
Method Effects ◽  
And Control

Advantages of microfluidic devices include miniaturization, easy of integration, small reagent consumption etc., and have led to the wide applications in biomedical field. Fabrication of microfluidic devices is commonly done through microfabrication methods; microfabication-free/using rapid prototyping methods have also been developed in recent years to enable applications of microfluidic devices to a broader range. Our recent study has demonstrated the feasibility of fabricating electrospun fiber embedded microfluidic devices by integrating hydrogel molding and electrospinning (ES) through a multi-layer construction process. This paper focuses on examining how process parameters affect microchannel formation in microfluidic devices fabricated using direct-deposition hydrogel molding (dHGM). PDMS (polydimethylsiloxane) was chosen as the base-material of the device, and Agarose hydrogel was used to generate the mold channels. A direct writing system was used to deposit the hydrogel mold. We examined three parameters affecting the dHGM based microchannel formation: hydrogel composition, curing conditions, and deposition method. Effects of these parameters were characterized in terms of ease-of-handling, consistent channel formation, and control of channel diameter.

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