A highly sensitive CE-chemiluminescence method for the determination of sympathomimetic drugs in urine samples by a facile precolumn derivatization using acridinium ester

2013 ◽  
Vol 35 (7) ◽  
pp. 1000-1003 ◽  
Author(s):  
Zuorong Wang ◽  
Huan Yue ◽  
Yonghong Wang ◽  
Lin Wang ◽  
Zhifeng Fu
Keyword(s):  
Urine Samples ◽  
Precolumn Derivatization ◽  
Chemiluminescence Method ◽  
Sympathomimetic Drugs ◽  
Highly Sensitive ◽  
Acridinium Ester

Development of a highly sensitive and selective spectrophotometric method for the determination of carvedilol in pharmaceutical and urine samples

RSC Advances ◽  
2014 ◽  
Vol 4 (77) ◽  
pp. 40816-40823
Author(s):  
Masoud Shariati-Rad ◽  
Mohsen Irandoust ◽  
Sara Sheikhi
Keyword(s):  
Spectrophotometric Method ◽  
Cost Effective ◽  
Urine Samples ◽  
Highly Sensitive

A simple, sensitive, selective, accurate and cost-effective spectrophotometric method for the determination of CAR in pharmaceutical and urine samples was developed.

A new chemiluminescence method for the determination of 8-hydroxyguanine based on l-histidine bound nickel nanoparticles

2020 ◽  
Vol 56 (48) ◽  
pp. 6535-6538
Author(s):  
Xi-Luan Yan ◽  
Meng-Meng Jiang ◽  
Ying Hu ◽  
Le Wu ◽  
Kun Zhao ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Nickel Nanoparticles ◽  
Synergistic Interaction ◽  
Urine Samples ◽  
Chemiluminescence Method ◽  
The Real

A new chemiluminescence aptasensor is constructed based on the synergistic interaction of Ni NPs@l-histidine@aptamer@MBs, which shows great potential for sensitive and efficient assay of 8-hydroxyguanine in the real urine samples of cancer patients.

Highly sensitive gas chromatographic determination of ethanol in human urine samples

2003 ◽  
Vol 798 (2) ◽  
pp. 179-186 ◽  
Author(s):  
Michael Zilly ◽  
Peter Langmann ◽  
Ulrike Lenker ◽  
Verena Satzinger ◽  
Diana Schirmer ◽  
...  
Keyword(s):  
Human Urine ◽  
Chromatographic Determination ◽  
Urine Samples ◽  
Human Urine Samples ◽  
Highly Sensitive

scholarly journals Determination of Phenolic Sympathomimetic Drugs in Pharmaceutical Samples and Biological Fluids by Flow-Injection Chemiluminescence

2000 ◽  
Vol 83 (6) ◽  
pp. 1299-1305 ◽  
Author(s):  
Fatma A Aly ◽  
Salma A Al-Tamimi ◽  
Abdulrahman A Alwarthan
Keyword(s):  
Formic Acid ◽  
Flow Injection ◽  
Reaction Pathway ◽  
Biological Fluids ◽  
Dosage Forms ◽  
Pharmaceutical Samples ◽  
Sympathomimetic Drugs ◽  
Highly Sensitive ◽  
Flow Injection Chemiluminescence

Abstract A rapid and highly sensitive flow-injection chemiluminometric method was developed for determination of 3 sympathomimetic drugs, namely, etilefrine hydrochloride, isoxsuprine hydrochloride, and prenalterol hydrochloride. The method is based on chemiluminescence induced by oxidation of drugs with acidified potassium permanganate in the presence of formic acid as a carrier. The calibration graphs were linear over the concentration ranges 0.2–9, 0.2–12.5, and 0.025–1.25 μg/mL for the 3 compounds, respectively. The method was applied successfully in determining the drugs in dosage forms and in biological fluids. A proposal for the reaction pathway is suggested.

Atomic absorption determination of mercury in urine by cold steam method using mercury- hydride prefix

2019 ◽  
Vol 1 (10) ◽  
pp. 887-891
Author(s):  
E. V. Moiseeva ◽  
I. A. Potapova
Keyword(s):  
Atomic Absorption ◽  
High Accuracy ◽  
The Body ◽  
Urine Samples ◽  
Minimal Cost ◽  
Atomic Absorption Determination ◽  
Absorption Determination ◽  
Highly Sensitive ◽  
Mercury In Urine

Mercury is one of the most common in various industries and at the same time dangerous chemicals. It is able to be deposited in the body and have a toxic effect for a long time after the cessation of contact. Under the influence of mercury, workers can develop various intoxications, as a result of which pathological changes in the nervous, cardiovascular, endocrine, immune and reproductive systems are possible.Under production conditions, mercury enters the body, usually in the form of vapors (absorbed about 80%) and suspended particles. Inorganic forms of mercury are excreted mainly in the urine (60%). However, insufficient attention is currently being paid to the problem of determining the mercury content in urine samples. To date, in world practice there is no systematic approach to the determination of small doses of mercury in the body, as a result of which it is difficult to timely identify public health disorders. This is largely due to the lack of highly sensitive and highly effective methods of analysis, allowing routine measurements with minimal cost and high accuracy. The methods currently used are either quite expensive or have low accuracy/sensitivity.The aim of the study was to develop a method of atomic absorption determination of mercury in urine by cold steam, which would allow at minimal cost to increase the accuracy and sensitivity of mercury detection in the body.Materials and methods. Quantitative measurement of mercury in urine samples was carried out on an atomic absorption spectrometer with a mercury-hydride prefix using model solutions of different concentrations.Results. The study determined the optimal conditions for sample preparation of urine samples, set the range of concentrations for the construction of the calibration schedule, studied the effect of the matrix on the accuracy of the analysis by the “introduced-found” method. The lower limit of detection of the developed technique was 0.05 mcg/l, the upper limit–100 mcg/l (if necessary, it can be increased by additional dilution). The relative error of determination depending on the concentration varied from 3 to 15%.Conclusions. A highly sensitive, affordable and relatively inexpensive method for the determination of mercury in urine has been developed, which will allow to diagnose with high accuracy the background contents of mercury in urine, which is especially important when inspecting workers of industries associated with the use of mercury and its compounds, as well as the population living in areas close to these industries.

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