Simultaneous determination of diclofenac and its common counter-ions in less than 1 minute using capillary electrophoresis with contactless conductivity detection

2013 ◽  
Vol 34 (9-10) ◽  
pp. 1423-1428 ◽  
Author(s):  
Rafael R. Cunha ◽  
Denise T. Gimenes ◽  
Rodrigo A. A. Munoz ◽  
Claudimir L. do Lago ◽  
Eduardo M. Richter
Keyword(s):  
Capillary Electrophoresis ◽  
Simultaneous Determination ◽  
Conductivity Detection ◽  
Contactless Conductivity Detection ◽  
Counter Ions

scholarly journals Simultaneous determination of three sulfanilamide artificial sweeteners in foodstuffs by capillary electrophoresis coupled with contactless conductivity detection based on porous aromatic frameworks enhanced solid phase extraction

2019 ◽  
Vol 97 (5) ◽  
pp. 344-351 ◽  
Author(s):  
Shaige Xia ◽  
Dan Yin ◽  
Yanlong Chen ◽  
Zhicong Yang ◽  
Ying Miao ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Solid Phase Extraction ◽  
Simultaneous Determination ◽  
Solid Phase ◽  
Artificial Sweeteners ◽  
Phase Extraction ◽  
Conductivity Detection ◽  
Contactless Conductivity Detection ◽  
Porous Aromatic Frameworks

In this paper, a simple and easy method of solid phase extraction (SPE) followed by capillary electrophoresis (CE) with capacitively coupled contactless conductivity detection (C4D) is evaluated as a novel approach for the simultaneous determination of acesulfame-K (ACE), sodium saccharin (SAC), and sodium cyclamate (CYC) in foodstuffs without derivatization. To reduce the complex matrix interference resulting from the constituents of samples and enriched targets, porous aromatic frameworks (PAFs) enhanced SPE, a suitable sample pretreatment procedure, was introduced. Several factors affecting extraction efficiency and electrophoretic separation were investigated. Additionally, the interaction mechanisms between the host (PAF-6) and guests (ACE, SAC, and CYC) were studied. Under the optimum conditions, three sulfanilamide artificial sweeteners were baseline separated within 8 min, exhibiting a linear calibration over two orders of magnitude (R2 > 0.995). The limits of detection (LOD) and quantification (LOQ) were considered better than those usually obtained by CE with ultraviolet and C4D detection. The proposed SPE–CE–C4D method has been successfully applied to analyse beverage samples and candied fruits with recoveries in the range of 78.89%–92.00%.

Fast determination of diphenhydramine, pyridoxine, and 8-chlorotheophylline by capillary electrophoresis with capacitively coupled contactless conductivity detection

2016 ◽  
Vol 8 (22) ◽  
pp. 4432-4437 ◽  
Author(s):  
Michelle M. A. C. Ribeiro ◽  
Jhonys M. Freitas ◽  
Rodrigo A. A. Muñoz ◽  
Claudimir L. do Lago ◽  
Eduardo M. Richter
Keyword(s):  
Capillary Electrophoresis ◽  
Simultaneous Determination ◽  
Fast Method ◽  
Conductivity Detection ◽  
Fast Determination ◽  
Capacitively Coupled ◽  
Contactless Conductivity Detection

This work reports a new and fast method for the simultaneous determination of diphenhydramine, pyridoxine, and 8-chlorotheophylline by CE-C4D.

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