Modification of Gold Electrode via Electrografting of the in situ Generated 3‐Carboxy‐1,2,4‐triazoldiazonium Salt for Label‐free Determination of Carcinoembryonic Antigen

2019 ◽  
Vol 32 (4) ◽  
pp. 698-705
Author(s):  
T. S. Svalova ◽  
A. A. Saigushkina ◽  
M. V. Medvedeva ◽  
N. N. Malysheva ◽  
V. O. Zhdanovskikh ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Gold Electrode ◽  
Label Free

scholarly journals Label-Free and Sensitive Determination of Cadmium Ions Using a Ti-Modified Co3O4-Based Electrochemical Aptasensor

Biosensors ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 195
Author(s):  
Yang Liu ◽  
Dongwei Zhang ◽  
Jina Ding ◽  
Kashif Hayat ◽  
Xijia Yang ◽  
...  
Keyword(s):  
Environmental Protection Agency ◽  
Concentration Limit ◽  
Co3o4 Nanoparticles ◽  
Label Free ◽  
Current Signal ◽  
Electrochemical Aptasensor ◽  
Screen Printed Carbon Electrode ◽  
Sensitive Determination

The current work demonstrates an electrochemical aptasensor for sensitive determination of Cd2+ based on the Ti-modified Co3O4 nanoparticles. In this unlabeled system, Ti-modified Co3O4 nanoparticles act as current signal amplifiers modified on the screen-printed carbon electrode (SPCE) surface, while the derivative aptamer of Cd2+ works as a target recognizer. In addition, the sensing is based on the increase in electrochemical probe thionine current signal due to the binding of aptamer to Cd2+ via specific recognition. In the current study, key parameters, including aptamer concentration, pH, and incubation time were optimized, respectively, to ensure sensing performance. Cyclic voltammetry was used not only to characterize each preparation and optimization step, but also to profile the bindings of aptamer to Cd2+. Under optimal conditions, Cd2+ can be determined in a linear range of 0.20 to 15 ng/mL, with a detection limit of 0.49 ng/mL, significantly below the maximum concentration limit set by the U.S. Environmental Protection Agency. Based on comparative analysis and the results of recovery test with real samples, this simple, label-free but highly selective method has considerable potential and thus can be used as an in-situ environmental monitoring platform for Cd2+ testing.

Real-time determination of carcinoembryonic antigen by using a contactless electrochemical immunosensor

2016 ◽  
Vol 8 (24) ◽  
pp. 4861-4866 ◽  
Author(s):  
Yan Jin ◽  
Hongju Mao ◽  
Qinghui Jin ◽  
Jianlong Zhao
Keyword(s):  
Detection Limit ◽  
Carcinoembryonic Antigen ◽  
Real Time ◽  
Specific Binding ◽  
Electrochemical Immunosensor ◽  
Label Free ◽  
Time Interaction ◽  
Time Determination ◽  
Impedance Immunosensor

A sensitive label-free and contactless impedance immunosensor is developed for the real-time interaction investigation between a cancer biomarker carcinoembryonic antigen (CEA) and its antibody CEA 5909. The immunosensor is proved to have a specific binding process between CEA and CEA 5909 with a detection limit of 100 fg mL−1in PBS.

scholarly journals Reagentless and sensitive determination of carcinoembryonic antigen based on a stable Prussian blue modified electrode

RSC Advances ◽  
2020 ◽  
Vol 10 (63) ◽  
pp. 38316-38322
Author(s):  
Jing Lin ◽  
Kunyin Li ◽  
Meifang Wang ◽  
Xiaohong Chen ◽  
Jiyang Liu ◽  
...  
Keyword(s):  
Electrochemical Sensor ◽  
Carcinoembryonic Antigen ◽  
Prussian Blue ◽  
Modified Electrode ◽  
Sensitive Detection ◽  
Label Free ◽  
Sensitive Determination

A label-free electrochemical sensor is easily fabricated based on stable and surface-confined Prussian blue for reagentless and sensitive detection of carcinoembryonic antigen.

Label-Free Electrochemical Aptasensor for Determination of Chloramphenicol Based on Gold Nanocubes-Modified Screen-Printed Gold Electrode

2015 ◽  
Vol 27 (6) ◽  
pp. 1449-1456 ◽  
Author(s):  
Ayemeh Bagheri Hashkavayi ◽  
Jahan Bakhsh Raoof ◽  
Reza Ojani ◽  
Ezat Hamidi Asl
Keyword(s):  
Gold Electrode ◽  
Label Free ◽  
Electrochemical Aptasensor ◽  
Screen Printed

Novel label-free electrochemical aptasensor for determination of Diazinon using gold nanoparticles-modified screen-printed gold electrode

2018 ◽  
Vol 120 ◽  
pp. 122-128 ◽  
Author(s):  
Shokoufeh Hassani ◽  
Milad Rezaei Akmal ◽  
Armin Salek-Maghsoudi ◽  
Soheila Rahmani ◽  
Mohammad Reza Ganjali ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Gold Electrode ◽  
Label Free ◽  
Electrochemical Aptasensor ◽  
Screen Printed

Study on the Novel Label Free Impedimetric Immunosensor for Aflatoxin B1 Based on Poly(o-phenylenediamine) Film Modified Gold Electrode

2011 ◽  
Vol 322 ◽  
pp. 385-389 ◽  
Author(s):  
Ning Ning Wu ◽  
Li Xin Cao ◽  
Pei Sheng Yan ◽  
Ming Hao Wang
Keyword(s):  
Aflatoxin B1 ◽  
Gold Electrode ◽  
Biomolecular Recognition ◽  
The Novel ◽  
Label Free ◽  
Buffer Solution ◽  
Solution Ph ◽  
Linear Detection ◽  
Impedimetric Immunosensor

A label free impedimetric immunosensor for the determination of aflatoxin B1 (AFB1) was fabricated by immobilizing anti-AFB1 onto Poly o-phenylenediamine (PoPD) electropolymerized film modified gold electrode by glutaraldehyde (GA) cross-linking. An electrochemical interfacial modeling of biomolecular recognition was recommended and reasonably interpreted. EIS technology was employed for the quantitative determination. The linear detection concentration ranges of AFB1 were 0.03~0.1 μg/mL and 0.1~0.7 μg/mL. The detection limit was 2.8×10-8μg/mL. The immunosensor could be reused more than 10 times when renewed by HCl-Glycine buffer solution (pH 2.6).

scholarly journals Simultaneous Adsorptive Cathodic Stripping Voltammetric Determination of Nickel(II) and Cobalt(II) at an In Situ Bismuth-Modified Gold Electrode

2013 ◽  
Vol 25 (11) ◽  
pp. 2471-2479 ◽  
Author(s):  
A. Mardegan ◽  
S. Dal Borgo ◽  
P. Scopece ◽  
L. M. Moretto ◽  
S. B. Hočevar ◽  
...  
Keyword(s):  
Gold Electrode ◽  
Voltammetric Determination ◽  
Determination Of Nickel ◽  
Cathodic Stripping
Sign in / Sign up

Export Citation Format

Share Document