Development and Application of a Voltammetric Biosensor Based on Polypyrrole/uricase/graphene for Uric Acid Determination

2017 ◽  
Vol 30 (1) ◽  
pp. 119-127 ◽  
Author(s):  
Juliana de Fátima Giarola ◽  
Valdir Mano ◽  
Arnaldo César Pereira
1979 ◽  
Vol 25 (4) ◽  
pp. 619-621 ◽  
Author(s):  
K Bartl ◽  
M Brandhuber ◽  
J Ziegenhorn

Abstract The enzymatic determination of serum uric acid by use of uricase, catalase, and aldehyde dehydrogenase according to Haeckel [J. Clin. Chem. Clin Biochem. 14, 101 (1976)] showed interferences from ethanol-converting enzymes, which are present in some patients' sera. We have identified these enzymes as alcohol dehydrogenase isoenzymes. Among other substances, a mixture of pyrazole and oxalate can be used to eliminate these interferences. This inhibitor system gives good results when used in the automated kinetic uric acid determination, as is shown by a comparison with the manual assay for uric acid according to Kageyama [Clin. Chim. Acta 31, 421 (1971)].


2015 ◽  
Vol 22 (10) ◽  
pp. 1212-1219 ◽  
Author(s):  
Mandy J. Schmella ◽  
Rebecca G. Clifton ◽  
Andrew D. Althouse ◽  
James M. Roberts

2006 ◽  
Vol 85 (5) ◽  
pp. 519-525 ◽  
Author(s):  
Jeltsje S. Cnossen ◽  
Hanna de Ruyter-Hanhijärvi ◽  
Joris A. M. van der Post ◽  
Ben W. J. Mol ◽  
Khalid S. Khan ◽  
...  

1980 ◽  
Vol 59 (3) ◽  
pp. 662-663 ◽  
Author(s):  
C. RUFFINI CASTROVILLI ◽  
M. RIGONI

2008 ◽  
Vol 62 (3) ◽  
Author(s):  
Suling Feng ◽  
Xueping Liu

AbstractA novel kinetic spectrofluorimetric method for the determination of uric acid based on the activation effect of uric acid on the Cu(II) ion catalyzed oxidation of pyronine Y by hydrogen peroxide was developed. The influence of different buffer solutions was tested and the Britton-Robinson buffer solution with pH 2.2 was found to be the optimum. The detection limit and the linear range for uric acid are 0.09 μg mL−1 and 0.3–3.0 μg mL−1, respectively. The RSD for eleven determinations of 1.6 μg mL−1 uric acid was 1.6 %. Satisfactory results were obtained when using this method of uric acid determination in human urine.


Author(s):  
Peter Wilding ◽  
David A. Heath

The effect of paracetamol on uric acid determination using a phosphotungstate reduction method has been investigated. The results show that apparently raised values of serum uric acid may be reported in patients receiving therapeutic levels of this drug. Levels of serum uric acid were determined over a five-hour period in three patients who had received therapeutic doses of paracetamol. The assays of serum uric acid were performed by a method based on phosphotungstate reduction and by one employing uricase. The results illustrate the problems of using the former method for clinical purposes.


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