Voltammetric Detection of Captopril on Graphite Screen Printed Electrodes

2015 ◽  
Vol 28 (4) ◽  
pp. 742-748 ◽  
Author(s):  
Madalena C. C. Areias ◽  
Her Shuang Toh ◽  
Patricia T. Lee ◽  
Richard G. Compton
2019 ◽  
Vol 51 (3) ◽  
pp. 305-311
Author(s):  
M. F. Khanfar ◽  
E. S. M. Abu-Nameh ◽  
A. T. Afaneh ◽  
M. M. Saket ◽  
A. Ahmad ◽  
...  

Electrochemical oxidation of hydrochlorothiazide (HCT) was investigated both experimentally and theoretically to explore the connection between thermodynamics and the oxidation potential. In this work, screen printed carbon electrodes were modified with molybdenum oxide by means of voltammetry. The modified surfaces demonstrated significant sensitivity toward hydrochlorothiazide detection in pH 2.00–buffered aqueous solutions. The employed method was validated and used for hydrochlorothiazide quantification in commercial drug products. In this work, we presented results of density functional calculations for the standard reduction potential of the HCT (H)2|HCT couple in aqueous solution. After consideration of 20 density functionals with 4 different basis sets, it was found that the hybrid meta functionals provide the most accurate prediction of the reduction potential in comparison with the available experimental data. The reported reduction potential is underestimated with GGA and MGGA and is overestimated with hybrid and meta hybrid functionals. Our results highlighted the importance of including solute-solvent hydrogen bonding effects in the theoretical modeling of redox processes. Keywords: Molybdenum oxide, Hydrochlorothiazide, Screen-printed electrodes, Electrochemical deposition, Density functional theory (DFT).


2012 ◽  
Vol 664 ◽  
pp. 100-104 ◽  
Author(s):  
Luigi Falciola ◽  
Valentina Pifferi ◽  
Maria Luisa Possenti ◽  
Veronica Carrara

Sensors ◽  
2020 ◽  
Vol 20 (12) ◽  
pp. 3609 ◽  
Author(s):  
Codruta Varodi ◽  
Florina Pogacean ◽  
Marin Gheorghe ◽  
Valentin Mirel ◽  
Maria Coros ◽  
...  

Flexible screen-printed electrodes (HP) were fabricated on stone paper substrate and amperometrically modified with gold nanoparticles (HP-AuNPs). The modified electrode displayed improved electronic transport properties, reflected in a low charge-transfer resistance (1220 Ω) and high apparent heterogeneous electron transfer rate constant (1.94 × 10−3 cm/s). The voltammetric detection of dopamine (DA) was tested with HP and HP-AuNPs electrodes in standard laboratory solutions (pH 6 phosphate-buffered saline (PBS)) containing various concentrations of analyte (10−7–10−3 M). As expected, the modified electrode exhibits superior performances in terms of linear range (10−7–10−3 M) and limit of detection (3 × 10−8 M), in comparison with bare HP. The determination of DA was tested with HP-AuNPs in spiked artificial urine and in pharmaceutical drug solution (ZENTIVA) that contained dopamine hydrochloride (5 mg/mL). The results obtained indicated a very good DA determination in artificial urine without significant matrix effects. In the case of the pharmaceutical drug solution, the DA determination was affected by the interfering species present in the vial, such as sodium metabisulfite, maleic acid, sodium chloride, and propylene glycol.


2011 ◽  
Vol 56 (11) ◽  
pp. 3988-3995 ◽  
Author(s):  
Elena Jubete ◽  
Kamila Żelechowska ◽  
Oscar A. Loaiza ◽  
Pedro J. Lamas ◽  
Estibalitz Ochoteco ◽  
...  

Author(s):  
Robert D. Crapnell ◽  
Whitchuta Jesadabundit ◽  
Alejandro García-Miranda Ferrari ◽  
Nina C. Dempsey-Hibbert ◽  
Marloes Peeters ◽  
...  

2021 ◽  
pp. 101055
Author(s):  
Dora Domnica Baciu ◽  
Ruxandra Bîrjega ◽  
Valentina Mărăscu ◽  
Rodica Zăvoianu ◽  
Andreea Matei ◽  
...  

2003 ◽  
Vol 481 (2) ◽  
pp. 209-211 ◽  
Author(s):  
Christine Bonnet ◽  
Silvana Andreescu ◽  
Jean-Louis Marty

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