Determination of Uric Acid and Norepinephrine by Chitosan-Multiwall Carbon Nanotube Modified Electrode

2005 ◽  
Vol 17 (10) ◽  
pp. 901-905 ◽  
Author(s):  
Guanghan Lu ◽  
Lingyan Jiang ◽  
Feng Song ◽  
Chuanyin Liu ◽  
Liping Jiang
Keyword(s):  
Uric Acid ◽  
Carbon Nanotube ◽  
Modified Electrode ◽  
Multiwall Carbon Nanotube ◽  
Multiwall Carbon

Multiwall carbon nanotube-modified electrode as a nanosensor for electrochemical studies and stripping voltammetric determination of an antimalarial drug

RSC Advances ◽  
2015 ◽  
Vol 5 (19) ◽  
pp. 14407-14415 ◽  
Author(s):  
Sayed Mehdi Ghoreishi ◽  
Abdol Mohammad Attaran ◽  
Atiyeh Moqadam Amin ◽  
Asma Khoobi
Keyword(s):  
Carbon Nanotube ◽  
Modified Electrode ◽  
Antimalarial Drug ◽  
Voltammetric Determination ◽  
Multiwall Carbon Nanotube ◽  
Electrochemical Studies ◽  
Multiwall Carbon

MWCNTs/CPE exhibited excellent effect towards the oxidation of hydroxychloroquine.

scholarly journals ELECTROCHEMICAL AND CHEMOMETRIC DETERMINATION OF DORZOLAMIDE AND TIMOLOL IN EYE DROPS USING MODIFIED MULTIWALL CARBON NANOTUBE ELECTRODE

2017 ◽  
Vol 9 (9) ◽  
pp. 43 ◽  
Author(s):  
Hassan A.m. Hendawy ◽  
Hanan M. Elwy ◽  
Amany M. Fekry
Keyword(s):  
Modified Electrode ◽  
Limit Of Detection ◽  
Partial Least Square ◽  
Least Square ◽  
Fractional Factorial ◽  
Great Promise ◽  
Multiwall Carbon Nanotube ◽  
Eye Drops ◽  
Multiwall Carbon

Objective: This work is focused on the construction of simple and sensitive electrochemical sensor for quantitative determination of dorzolamide (DOR) and timolol maleate (TIM). This method is based on the incorporation of multiwall carbon nanotubes (MWCNT) into the carbon paste electrode which improve the characteristics of the electrode.Methods: The electrochemical response of modified electrode was based on voltammetric oxidation, using cyclic voltammetry (CV) and impedance spectroscopy (EIS). The structural morphology of the surface modified electrode was characterized by scanning electron microscope (SEM). Quantitative analysis for each of the two compounds in a mixture has been examined by using of chemometric tools for resolving overlapping signals. The prediction performance of the chemometric method was analyzed by principal component regression (PCR) and partial least square (PLS).Results: Fractional factorial design was constructed from set of synthetic mixtures of two drugs in concentration ranges of 0.05 to 1.6µg/ml for DOR and 1.5-20 µg/ml for TIM. Under optimum experimental conditions, DOR and TIM gave rectilinear response over the concentration range of 0.072-1.88 µg/ml and 1.16-20.84 µg/ml, respectively. The limit of detection (LOD) was found to be 0.098 and 1.025 µg/ml, for DOR and TIM, respectively. It found that the % of relative prediction error (RPE) was acceptable and satisfactory.Conclusion: In these work, for the first time, a new voltammetric simultaneous method developed for a rapid and efficient determination of DOR and TIM from eye dropper sample at nano modified electrode with satisfactory results. These results indicate that MWCNT holds great promise in practical application.

Fabrication of Graphene/Carbon Nanotube Composite Modified Electrode for Selective and Sensitive Determination of Uric Acid

2013 ◽  
Vol 641-642 ◽  
pp. 562-565
Author(s):  
Zheng Xiao Liu ◽  
Jian Fei Xia ◽  
Zong Hua Wang ◽  
Yan Zhi Xia ◽  
Fei Fei Zhang ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Uric Acid ◽  
Carbon Nanotube ◽  
Modified Electrode ◽  
Phosphate Buffer Solution ◽  
Carbon Electrode ◽  
Buffer Solution ◽  
Sensitive Determination ◽  
Carbon Nanotube Composite

A novel composite was firstly synthesized by compositing graphenes (G) and carbon nanotubes (CNTs) and then a new composite modified electrode (G/CNTs/GCE) was prepared by coating the resulting composite on the surface of the glassy carbon electrode (GCE). The composite modified electrode G/CNTs/GCE showed great electrochemical activities which were studied by sensitive determining the electrochemistry behaviors of uric acid (UA). It revealed when the concentration range of UA changed from 1×10-7 mol/L to 1×10-3 mol/L, the peak currents had linear relationship with the concentration of UA in the phosphate buffer solution (PBS) which the value of pH is 7.0. And the linear equation is ip (μA) = 21.55C+28.94 (C: mmol/L), with the related coefficient 0.9964.

Sign in / Sign up

Export Citation Format

Share Document